Comparison of strategies to reduce sperm DNA fragmentation in couples undergoing ICSI

We read with interest the commentary by Drs. Jan Tesarik and Maribel Galan-Lazaro (1) regarding the recently published practice recommendations for sperm DNA fragmentation (SDF) testing based on clinical scenarios by Agarwal et al . (2).

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[2]  J. Tesarik,et al.  Clinical scenarios of unexplained sperm DNA fragmentation and their management , 2017, Translational Andrology and Urology.

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[5]  Sajal Gupta,et al.  Abstinence Time and Its Impact on Basic and Advanced Semen Parameters. , 2016, Urology.

[6]  S. Esteves,et al.  Comparison of reproductive outcome in oligozoospermic men with high sperm DNA fragmentation undergoing intracytoplasmic sperm injection with ejaculated and testicular sperm. , 2015, Fertility and sterility.

[7]  M. Chehrazi,et al.  Hyaluronic Acid Binding Assay Is Highly Sensitive to Select Human Spermatozoa with Good Progressive Motility, Morphology, and Nuclear Maturity , 2015, Gynecologic and Obstetric Investigation.

[8]  Wenhao Shi,et al.  Efficacy of swim-up versus density gradient centrifugation in improving sperm deformity rate and DNA fragmentation index in semen samples from teratozoospermic patients , 2014, Journal of Assisted Reproduction and Genetics.

[9]  E. Isachenko,et al.  Quality of human spermatozoa: relationship between high‐magnification sperm morphology and DNA integrity , 2014, Andrologia.

[10]  F. Vialard,et al.  Selection of normal spermatozoa with a vacuole‐free head (x6300) improves selection of spermatozoa with intact DNA in patients with high sperm DNA fragmentation rates , 2013, Andrologia.

[11]  J. Gosálvez,et al.  Shorter abstinence decreases sperm deoxyribonucleic acid fragmentation in ejaculate. , 2011, Fertility and sterility.

[12]  A. Borini,et al.  Annexin V magnetic-activated cell sorting versus swim-up for the selection of human sperm in ART: is the new approach better then the traditional one? , 2011, Journal of Assisted Reproduction and Genetics.

[13]  Chun-Chia Huang,et al.  Magnetic-activated cell sorting for sperm preparation reduces spermatozoa with apoptotic markers and improves the acrosome reaction in couples with unexplained infertility. , 2010, Human reproduction.

[14]  T. Hannam,et al.  Testicular spermatozoa have statistically significantly lower DNA damage compared with ejaculated spermatozoa in patients with unsuccessful oral antioxidant treatment. , 2010, Fertility and sterility.

[15]  L. Parmegiani,et al.  "Physiologic ICSI": hyaluronic acid (HA) favors selection of spermatozoa without DNA fragmentation and with normal nucleus, resulting in improvement of embryo quality. , 2010, Fertility and sterility.

[16]  J. Gosálvez,et al.  DNA Fragmentation Dynamics in Fresh Versus Frozen Thawed Plus Gradient-Isolated Human Spermatozoa , 2010, Systems biology in reproductive medicine.

[17]  C. Niederberger.  Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular spermatozoa. , 2005, The Journal of urology.

[18]  S. Esteves,et al.  Unpacking the mysteries of sperm DNA fragmentation Ten frequently asked questions , 2015 .