Translational bioinformatics in healthcare: past, present, and future

Abstract Back in 2003, chemists, biologists, statisticians, and computational scientists came together on one platform and brought out the entire human genome, known as The Human Genome Project. The completion of the project not only provided genomic data but also led to the formation of many new branches. Bioinformatics is like an ameba: it does not have any specific shape or size. It has grown from simple genomic analysis and expanded itself to omics-based analysis, drug designing and discovery, network biology, expression analysis, epigenetics, immunology, cheminformatics, and so on. This chapter highlights the trend change from the germination of bioinformatics to its growth in various domains of biologic, chemical, physical, and computational sciences, making it translational bioinformatics. The purpose of this chapter is to systematically introduce fundamental concepts of translational bioinformatics, its scope, and applications in healthcare, ethical issues related to the use of personal genome in healthcare, and its future perspectives for better healthcare management.

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