Short-Term Synaptic Plasticity and Adaptation Contribute to the Coding of Timing and Intensity Information

In birds, the cochlear nucleus angularis (NA) is an obligatory relay for intensity processing, and the nucleus magnocellularis (NM) serves the same function for temporal information. Our recent experimental and modeling studies have shown that short-term synaptic plasticity is a major player in this division into parallel pathways. Short-term synaptic plasticity, by dynamically modulating synaptic strength, filters information contained in the firing patterns.

[1]  M. Konishi,et al.  Segregation of stimulus phase and intensity coding in the cochlear nucleus of the barn owl , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[2]  M. Sachs,et al.  Classification of unit types in the anteroventral cochlear nucleus: PST histograms and regularity analysis. , 1989, Journal of neurophysiology.

[3]  S. Laughlin The role of sensory adaptation in the retina. , 1989, The Journal of experimental biology.

[4]  M. Konishi,et al.  A circuit for detection of interaural time differences in the brain stem of the barn owl , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[5]  C. Köppl Phase Locking to High Frequencies in the Auditory Nerve and Cochlear Nucleus Magnocellularis of the Barn Owl, Tyto alba , 1997, The Journal of Neuroscience.

[6]  Masakazu Konishi,et al.  Cochlear and Neural Delays for Coincidence Detection in Owls , 2001, The Journal of Neuroscience.

[7]  Harunori Ohmori,et al.  Synaptic depression improves coincidence detection in the nucleus laminaris in brainstem slices of the chick embryo , 2002, The European journal of neuroscience.

[8]  P. Schwindt,et al.  Synaptic depression in the localization of sound , 2003, Nature.

[9]  Christine Köppl,et al.  Computational diversity in the cochlear nucleus angularis of the barn owl. , 2003, Journal of neurophysiology.

[10]  Hermann Wagner,et al.  A temporal window for lateralization of interaural time difference by barn owls , 1991, Journal of Comparative Physiology A.

[11]  T. Parsons,et al.  Evidence That Rapid Vesicle Replenishment of the Synaptic Ribbon Mediates Recovery from Short-Term Adaptation at the Hair Cell Afferent Synapse , 2004, Journal of the Association for Research in Otolaryngology.

[12]  Intracellular study of auditory coincidence detector neurons in owls , 2004 .

[13]  K M MacLeod,et al.  A role for short-term synaptic facilitation and depression in the processing of intensity information in the auditory brain stem. , 2007, Journal of neurophysiology.

[14]  C. Carr,et al.  Beyond timing in the auditory brainstem: intensity coding in the avian cochlear nucleus angularis. , 2007, Progress in brain research.

[15]  Masakazu Konishi,et al.  Passive soma facilitates submillisecond coincidence detection in the owl's auditory system. , 2007, Journal of neurophysiology.

[16]  Masakazu Konishi,et al.  How the Owl Tracks Its Prey , 2012 .