Potential for the Repurposing of Adamantane Antivirals for COVID-19

[1]  W. Danysz,et al.  Amantadine Inhibits SARS-CoV-2 In Vitro , 2021, Viruses.

[2]  G. Aranda-Abreu,et al.  Amantadine in the prevention of clinical symptoms caused by SARS-CoV-2 , 2021, Pharmacological Reports.

[3]  Amantadine Treatment for Parkinson’s Disease during COVID-19: Bimodal Action Targeting Viral Replication and the NMDA Receptor , 2020, Journal of Parkinson’s Disease and Alzheimer’s Disease.

[4]  Amantadine for the Treatment of Parkinson’s Disease and its Associated Dyskinesias , 2020, Journal of Parkinson’s Disease and Alzheimer’s Disease.

[5]  M. G. Jeppesen,et al.  Amantadin has potential for the treatment of COVID-19 because it targets known and novel ion channels encoded by SARS-CoV-2 , 2020 .

[6]  A. Baig,et al.  Docking Prediction of Amantadine in the Receptor Binding Domain of Spike Protein of SARS-CoV-2. , 2020, ACS pharmacology & translational science.

[7]  A. Kolocouris,et al.  Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers , 2020, Nature Structural & Molecular Biology.

[8]  Weijin Huang,et al.  Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development , 2020, Signal Transduction and Targeted Therapy.

[9]  Zhonglin Li,et al.  Underlying Mechanisms and Candidate Drugs for COVID-19 Based on the Connectivity Map Database , 2020, Frontiers in Genetics.

[10]  D. Kwon,et al.  A retrospective review of memantine use and COVID‐19‐associated mortality from a national database , 2020, Journal of medical virology.

[11]  I. Arkin,et al.  SARS-CoV-2 E protein is a potential ion channel that can be inhibited by Gliclazide and Memantine , 2020, Biochemical and Biophysical Research Communications.

[12]  F. Serdarevic,et al.  Potential role of memantine in the prevention and treatment of COVID-19: its antagonism of nicotinic acetylcholine receptors and beyond , 2020, European Respiratory Journal.

[13]  G. Aranda-Abreu,et al.  Use of amantadine in a patient with SARS‐CoV‐2 , 2020, Journal of medical virology.

[14]  Konrad Rejdak,et al.  Adamantanes might be protective from COVID-19 in patients with neurological diseases: multiple sclerosis, parkinsonism and cognitive impairment , 2020, Multiple Sclerosis and Related Disorders.

[15]  M. Polymeropoulos,et al.  Amantadine disrupts lysosomal gene expression: A hypothesis for COVID19 treatment , 2020, International Journal of Antimicrobial Agents.

[16]  Gonzalo Emiliano Aranda Abreu,et al.  Amantadine as a drug to mitigate the effects of COVID-19 , 2020, Medical Hypotheses.

[17]  T. Hashikawa,et al.  Response to Commentary on: "The neuroinvasive potential of SARS-CoV-2 may play a role in the respiratory failure of COVID-19 patients". , 2020, Journal of medical virology.

[18]  N. Cimolai,et al.  Potentially repurposing adamantanes for COVID‐19 , 2020, Journal of medical virology.

[19]  S. Brenner.  Repurposing of Adamantanes with Transmitter Receptor Antagonist Properties for the Prevention/Treatment of COVID-19 , 2020 .

[20]  R. Butterworth.  Amantadine for the Treatment of Traumatic Brain Injury and its Associated Cognitive and Neurobehavioral Complications , 2020 .

[21]  Yan Li,et al.  Structural model of the SARS coronavirus E channel in LMPG micelles , 2018, Biochimica et Biophysica Acta (BBA) - Biomembranes.

[22]  Antonios Kolocouris,et al.  Aminoadamantanes with Persistent in Vitro Efficacy against H1N1 (2009) Influenza A , 2014, Journal of medicinal chemistry.

[23]  M. Desforges,et al.  Novel Treatment with Neuroprotective and Antiviral Properties against a Neuroinvasive Human Respiratory Virus , 2013, Journal of Virology.

[24]  R. Lamb,et al.  Inhibitors of the Influenza A Virus M2 Proton Channel Discovered Using a High-Throughput Yeast Growth Restoration Assay , 2013, PloS one.

[25]  Jie Zhou,et al.  The Adamantane-Derived Bananins Are Potent Inhibitors of the Helicase Activities and Replication of SARS Coronavirus , 2005, Chemistry & Biology.

[26]  H. R. Payne,et al.  Initial events in bovine coronavirus infection: analysis through immunogold probes and lysosomotropic inhibitors , 2005, Archives of Virology.

[27]  A. Bukrinskaya,et al.  Rimantadine hydrochloride blocks the second step of influenza virus uncoating , 2005, Archives of Virology.

[28]  Y. Guan,et al.  In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds , 2004, Journal of Clinical Virology.

[29]  E. De Clercq,et al.  Synthesis and antiviral activity evaluation of some new aminoadamantane derivatives. 2. , 1996, Journal of medicinal chemistry.

[30]  E. De Clercq,et al.  Synthesis and antiviral activity evaluation of some new aminoadamantane derivatives. 2. , 1994 .

[31]  A. S. Beare,et al.  In Vitro Antiviral Activity and Preliminary Clinical Trials of a New Adamantane Compound , 1973, Antimicrobial Agents and Chemotherapy.