A pan-cancer genome-wide analysis reveals tumour dependencies by induction of nonsense-mediated decay
暂无分享,去创建一个
C. Yau | Zhiyuan Hu | A. Ahmed
[1] Niels H. Gehring,et al. Harnessing short poly(A)-binding protein-interacting peptides for the suppression of nonsense-mediated mRNA decay , 2016, Scientific Reports.
[2] Jay Shendure,et al. Classification and characterization of microsatellite instability across 18 cancer types , 2016, Nature Medicine.
[3] A. Ridley,et al. The RNA‐binding protein LARP4 regulates cancer cell migration and invasion , 2016, Cytoskeleton.
[4] Hong-Li Yan,et al. eIF5B increases ASAP1 expression to promote HCC proliferation and invasion , 2016, Oncotarget.
[5] F. Supek,et al. The rules and impact of nonsense-mediated mRNA decay in human cancers , 2016, Nature Genetics.
[6] A. Børresen-Dale,et al. Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer , 2016, Cell reports.
[7] Mary Goldman,et al. Rapid and efficient analysis of 20,000 RNA-seq samples with Toil , 2016, bioRxiv.
[8] L. Maquat,et al. Leveraging Rules of Nonsense-Mediated mRNA Decay for Genome Engineering and Personalized Medicine , 2016, Cell.
[9] F. Lejeune. Triple Effect of Nonsense-Mediated mRNA Decay Inhibition as a Therapeutic Approach for Cancer , 2016 .
[10] S. Miyano,et al. Identification of RNA-Binding Protein LARP4B as a Tumor Suppressor in Glioma. , 2016, Cancer research.
[11] Alan Ashworth,et al. BRCAness revisited , 2016, Nature Reviews Cancer.
[12] S. Blagden,et al. The La-Related Proteins, a Family with Connections to Cancer , 2015, Biomolecules.
[13] L. Maquat,et al. Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics , 2015, Nature Communications.
[14] Lawrence B. Gardner,et al. Stress-induced inhibition of nonsense mediated RNA decay regulates intracellular cystine transport and intracellular glutathione through regulation of the cystine/glutamate exchanger SLC7A11 , 2014, Oncogene.
[15] M. Kool,et al. The G-protein Alpha Subunit Gsα Is A Tumor Suppressor In Sonic Hedgehog-driven Medulloblastoma , 2014, Nature Medicine.
[16] I. Shih,et al. Roles of deletion of Arid1a, a tumor suppressor, in mouse ovarian tumorigenesis. , 2014, Journal of the National Cancer Institute.
[17] Shibing Deng,et al. Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer , 2014, Nature Genetics.
[18] D. Piwnica-Worms,et al. Intracellular Calcium Regulates Nonsense-Mediated mRNA Decay , 2014, Nature Medicine.
[19] Benjamin J. Raphael,et al. Mutational landscape and significance across 12 major cancer types , 2013, Nature.
[20] Joshua A. Arribere,et al. Roles for transcript leaders in translation and mRNA decay revealed by transcript leader sequencing , 2013, Genome research.
[21] P. Tonin,et al. An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer , 2012, Oncogene.
[22] Colin N. Dewey,et al. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome , 2011, BMC Bioinformatics.
[23] J. Zavadil,et al. Inhibition of Nonsense-Mediated RNA Decay by the Tumor Microenvironment Promotes Tumorigenesis , 2011, Molecular and Cellular Biology.
[24] Rachid Karam,et al. Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay. , 2011, Molecular cell.
[25] J. Rousset,et al. Rescue of non-sense mutated p53 tumor suppressor gene by aminoglycosides , 2010, Nucleic acids research.
[26] Mingming Jia,et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer , 2010, Nucleic Acids Res..
[27] E. Gilboa,et al. Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay , 2010, Nature.
[28] Matthew Mort,et al. A meta‐analysis of nonsense mutations causing human genetic disease , 2008, Human mutation.
[29] J. Tazi,et al. Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies , 2007, The Journal of cell biology.
[30] L. Maquat,et al. Applying nonsense-mediated mRNA decay research to the clinic: progress and challenges. , 2006, Trends in molecular medicine.
[31] G. Dreyfuss,et al. Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. , 2006, Genes & development.
[32] R. Mantovani,et al. DNA Damage Promotes Histone Deacetylase 4 Nuclear Localization and Repression of G2/M Promoters, via p53 C-terminal Lysines* , 2006, Journal of Biological Chemistry.
[33] Tony Pawson,et al. Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer , 2004, Nature Genetics.
[34] S. Markowitz,et al. Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability , 2004, Oncogene.
[35] H. Sweeney,et al. Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice. , 1999, The Journal of clinical investigation.
[36] M. Culbertson,et al. RNA surveillance. Unforeseen consequences for gene expression, inherited genetic disorders and cancer. , 1999, Trends in genetics : TIG.
[37] L. Maquat,et al. At Least One Intron Is Required for the Nonsense-Mediated Decay of Triosephosphate Isomerase mRNA: a Possible Link between Nuclear Splicing and Cytoplasmic Translation , 1998, Molecular and Cellular Biology.
[38] L. Maquat,et al. A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance. , 1998, Trends in biochemical sciences.
[39] J. Clancy,et al. Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line , 1997, Nature Medicine.
[40] R. Losson,et al. Interference of nonsense mutations with eukaryotic messenger RNA stability. , 1979, Proceedings of the National Academy of Sciences of the United States of America.
[41] A. Knudson. Mutation and cancer: statistical study of retinoblastoma. , 1971, Proceedings of the National Academy of Sciences of the United States of America.
[42] Steven A. Roberts,et al. Mutational heterogeneity in cancer and the search for new cancer genes , 2014 .
[43] H. Dietz,et al. Nonsense-mediated mRNA decay in health and disease. , 1999, Human molecular genetics.
[44] S. Rivella,et al. Identi fi cation and Characterization of Small Molecules That Inhibit Nonsense-Mediated RNA Decay and Suppress Nonsense p53 Mutations , 2022 .