Hemoglobin‐Related Biomaterials and their Applications

[1]  Junhui Sun,et al.  Protein-Crowned Micelles for Targeted and Synergistic Tumor-Associated Macrophage Reprogramming to Enhance Cancer Treatment. , 2022, Nano letters.

[2]  Daidi Fan,et al.  Artificial Nonenzymatic Antioxidant MXene Nanosheet-Anchored Injectable Hydrogel as a Mild Photothermal-Controlled Oxygen Release Platform for Diabetic Wound Healing. , 2022, ACS nano.

[3]  Zhenzhong Zhang,et al.  Engineered Nanoerythrocytes Alleviate Central Nervous System Inflammation by Regulating the Polarization of Inflammatory Microglia , 2022, Advanced materials.

[4]  Xinghai Ning,et al.  Biomimetic Activator of Sonodynamic Ferroptosis Amplifies Inherent Peroxidation for Improving the Treatment of Breast Cancer. , 2022, Small.

[5]  Minjie Wei,et al.  Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy , 2022, Theranostics.

[6]  Dong Wang,et al.  A hydrogen peroxide economizer for on-demand oxygen production-assisted robust sonodynamic immunotherapy , 2022, Theranostics.

[7]  A. Mozzarelli,et al.  From hemoglobin allostery to hemoglobin-based oxygen carriers. , 2021, Molecular aspects of medicine.

[8]  Xiaolong Liu,et al.  Engineered Red Blood Cell Biomimetic Nanovesicle with Oxygen Self-Supply for Near-Infrared-II Fluorescence-Guided Synergetic Chemo-Photodynamic Therapy against Hypoxic Tumors. , 2021, ACS applied materials & interfaces.

[9]  Shuixing Zhang,et al.  Tumor-Associated Macrophages and Their Functional Transformation in the Hypoxic Tumor Microenvironment , 2021, Frontiers in Immunology.

[10]  M. Salmerón-Sánchez,et al.  Engineered living biomaterials , 2021, Nature Reviews Materials.

[11]  Chen Jiang,et al.  Macrophage‐Disguised Manganese Dioxide Nanoparticles for Neuroprotection by Reducing Oxidative Stress and Modulating Inflammatory Microenvironment in Acute Ischemic Stroke , 2021, Advanced science.

[12]  Yubin Huang,et al.  Engineering Endogenous Tumor‐Associated Macrophage‐Targeted Biomimetic Nano‐RBC to Reprogram Tumor Immunosuppressive Microenvironment for Enhanced Chemo‐Immunotherapy , 2021, Advanced materials.

[13]  K. Imai,et al.  A Novel Oxygen Carrier (M101) Attenuates Ischemia-Reperfusion Injuries during Static Cold Storage in Steatotic Livers , 2021, International journal of molecular sciences.

[14]  Chunzhen Yang,et al.  A Robust Oxygen-Carrying Hemoglobin-Based Natural Sonosensitizer for Sonodynamic Cancer Therapy. , 2021, Nano letters.

[15]  T. Chen,et al.  Synergistical Starvation and Chemo‐Dynamic Therapy for Combating Multidrug‐Resistant Bacteria and Accelerating Diabetic Wound Healing , 2021, Advanced healthcare materials.

[16]  F. Zal,et al.  Therapeutic Potential of Hemoglobin Derived from the Marine Worm Arenicola marina (M101): A Literature Review of a Breakthrough Innovation , 2021, Marine drugs.

[17]  P. Convertini,et al.  Cancer Cell Metabolism in Hypoxia: Role of HIF-1 as Key Regulator and Therapeutic Target , 2021, International journal of molecular sciences.

[18]  K. Salnikow.  Role of Iron in Cancer. , 2021, Seminars in cancer biology.

[19]  Qianhao Min,et al.  Adapting and Remolding: Orchestrating Tumor Microenvironment Normalization with Photodynamic Therapy by Size Transformable Nanoframeworks. , 2021, Angewandte Chemie.

[20]  Xinyue Zhao,et al.  An Activatable Near-Infrared Fluorescence Hydrogen Sulfide (H2S) Donor for Imaging H2S Release and Inhibiting Inflammation in Cells. , 2021, Analytical chemistry.

[21]  Yu Chen,et al.  Emerging Nanomedicine‐Enabled/Enhanced Nanodynamic Therapies beyond Traditional Photodynamics , 2021, Advanced materials.

[22]  S. Zaman,et al.  Role of hydrogen sulfide donors in cancer development and progression , 2021, International journal of biological sciences.

[23]  C. Deng,et al.  Oxygen‐Enriched Metal‐Phenolic X‐Ray Nanoprocessor for Cancer Radio‐Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy , 2020, Advanced science.

[24]  Xuetao Shi,et al.  Antibacterial peptide-modified collagen nanosheet for infected wound repair , 2021, Smart Materials in Medicine.

[25]  Huijing Zhao,et al.  Bio-macromolecules/modified-halloysite composite hydrogel used as multi-functional wound dressing , 2021, Smart Materials in Medicine.

[26]  F. Zal,et al.  Combating hypoxemia in COVID-19 patients with a natural oxygen carrier, HEMO2Life® (M101) , 2020, Medical Hypotheses.

[27]  S. Dong,et al.  Microenvironment in subchondral bone: predominant regulator for the treatment of osteoarthritis , 2020, Annals of the Rheumatic Diseases.

[28]  Jian Shen,et al.  Injectable In Situ Self-Cross-Linking Hydrogels Based on Hemoglobin, Carbon Quantum Dots, and Sodium Alginate for Real-Time Detection of Wound Bacterial Infection and Efficient Postoperative Prevention of Tumor Recurrence. , 2020, Langmuir : the ACS journal of surfaces and colloids.

[29]  Jun Lin,et al.  Recent Advances in Nanomaterial‐Assisted Combinational Sonodynamic Cancer Therapy , 2020, Advanced materials.

[30]  Yuxin Shi,et al.  Hemoglobin-mediated biomimetic synthesis of paramagnetic O2-evolving theranostic nanoprobes for MR imaging-guided enhanced photodynamic therapy of tumor , 2020, Theranostics.

[31]  Yuanjin Zhao,et al.  Bioinspired Adhesive and Antibacterial Microneedles for Versatile Transdermal Drug Delivery , 2020, Research.

[32]  Songtao Zhang,et al.  Defect modified zinc oxide with augmenting sonodynamic reactive oxygen species generation. , 2020, Biomaterials.

[33]  Xiaoxuan Zhang,et al.  Black Phosphorus-Loaded Separable Microneedles as Responsive Oxygen-Delivery Carriers for Wound Healing. , 2020, ACS nano.

[34]  J. Guan,et al.  Nanoparticle-based drug delivery systems for cancer therapy , 2020, Smart materials in medicine.

[35]  Yueqing Gu,et al.  Enhanced Ferroptosis by Oxygen-Boosted Phototherapy Based on 2-in-1 Nanoplatform of Ferrous Hemoglobin for Tumor Synergistic Therapy. , 2020, ACS nano.

[36]  A. Fago,et al.  A novel possible role for met hemoglobin as carrier of H2S in the blood. , 2020, Antioxidants & redox signaling.

[37]  M. Singh,et al.  Artificial Blood: A Futuristic Dimension of Modern Day Transfusion 
Sciences , 2019, Cardiovascular & Hematological Agents in Medicinal Chemistry.

[38]  Eun Seong Lee,et al.  Near infrared light-responsive heat-emitting hemoglobin hydrogels for photothermal cancer therapy. , 2019, Colloids and surfaces. B, Biointerfaces.

[39]  Shu Wang.  Hemoglobin-Linked Conjugated Polymer Nanoparticles for Self-Luminescing and Oxygen Self-Supplying Phototherapy. , 2019, Angewandte Chemie.

[40]  Qinghui Wang,et al.  Oxygen Self-Production Red Blood Cell Carrier System for MRI Mediated Cancer Therapy: Ferryl-Hb, Sonodynamic, and Chemical Therapy. , 2018, ACS biomaterials science & engineering.

[41]  S. Hickman,et al.  Microglia in neurodegeneration , 2018, Nature Neuroscience.

[42]  L. Hosta-Rigau,et al.  Recent and prominent examples of nano- and microarchitectures as hemoglobin-based oxygen carriers. , 2018, Advances in colloid and interface science.

[43]  Wei Li,et al.  Hypoxic tumor therapy by hemoglobin-mediated drug delivery and reversal of hypoxia-induced chemoresistance. , 2018, Biomaterials.

[44]  Xian‐Zheng Zhang,et al.  Aggressive Man‐Made Red Blood Cells for Hypoxia‐Resistant Photodynamic Therapy , 2018, Advanced materials.

[45]  Zhenyu Luo,et al.  Bioinspired Hybrid Protein Oxygen Nanocarrier Amplified Photodynamic Therapy for Eliciting Anti-tumor Immunity and Abscopal Effect. , 2018, ACS nano.

[46]  A. Fago,et al.  Reactions of ferric hemoglobin and myoglobin with hydrogen sulfide under physiological conditions. , 2018, Journal of inorganic biochemistry.

[47]  X. Jing,et al.  Ion-assisted fabrication of neutral protein crosslinked sodium alginate nanogels. , 2018, Carbohydrate polymers.

[48]  Yu Chen,et al.  Nanoenzyme-Augmented Cancer Sonodynamic Therapy by Catalytic Tumor Oxygenation. , 2018, ACS nano.

[49]  P. Das,et al.  Blood Dots: Hemoglobin-Derived Carbon Dots as Hydrogen Peroxide Sensors and Pro-Drug Activators , 2018 .

[50]  Xuesi Chen,et al.  A Versatile Method to Prepare Protein Nanoclusters for Drug Delivery. , 2018, Macromolecular bioscience.

[51]  Xuesi Chen,et al.  Compact Vesicles Self-Assembled from Binary Graft Copolymers with High Hydrophilic Fraction for Potential Drug/Protein Delivery. , 2017, ACS macro letters.

[52]  Lanlan Liu,et al.  Cancer Cell Membrane‐Biomimetic Oxygen Nanocarrier for Breaking Hypoxia‐Induced Chemoresistance , 2017 .

[53]  X. Jing,et al.  A facile way to prepare functionalized dextran nanogels for conjugation of hemoglobin. , 2017, Colloids and surfaces. B, Biointerfaces.

[54]  M. Otagiri,et al.  Comparison of the Pharmacokinetic Properties of Hemoglobin-Based Oxygen Carriers , 2017, Journal of functional biomaterials.

[55]  Athol U. Wells,et al.  Idiopathic pulmonary fibrosis , 2012, Nature Reviews Disease Primers.

[56]  A. Sen Gupta.  Bio-inspired nanomedicine strategies for artificial blood components. , 2017, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

[57]  P. Netti,et al.  Hemoglobin‐Conjugated Gelatin Microsphere as a Smart Oxygen Releasing Biomaterial , 2016, Advanced healthcare materials.

[58]  R. Ransohoff.  How neuroinflammation contributes to neurodegeneration , 2016, Science.

[59]  M. Otagiri,et al.  Evaluation of a new type of nano-sized carbon monoxide donor on treating mice with experimentally induced colitis. , 2016, Journal of controlled release : official journal of the Controlled Release Society.

[60]  Junbai Li,et al.  Hemoglobin‐Based Nanoarchitectonic Assemblies as Oxygen Carriers , 2016, Advanced materials.

[61]  S. Saeed,et al.  Inflammatory Bowel Disease in Children and Adolescents. , 2021, Advances in pediatrics.

[62]  Hao Zhang,et al.  Cupreous Complex-Loaded Chitosan Nanoparticles for Photothermal Therapy and Chemotherapy of Oral Epithelial Carcinoma. , 2015, ACS applied materials & interfaces.

[63]  Xuesi Chen,et al.  Protein-Resistant Biodegradable Amphiphilic Graft Copolymer Vesicles as Protein Carriers. , 2015, Macromolecular bioscience.

[64]  H. Horinouchi,et al.  Carbon monoxide-bound hemoglobin-vesicles for the treatment of bleomycin-induced pulmonary fibrosis. , 2014, Biomaterials.

[65]  A. Sen Gupta,et al.  Synthetic approaches to RBC mimicry and oxygen carrier systems. , 2013, Biomacromolecules.

[66]  C. Lewis,et al.  Macrophage regulation of tumor responses to anticancer therapies. , 2013, Cancer cell.

[67]  T. Ørntoft,et al.  Tumor‐promoting macrophages induce the expression of the macrophage‐specific receptor CD163 in malignant cells , 2012, International journal of cancer.

[68]  J. Jahr,et al.  Crosslinked, polymerized, and PEG-conjugated hemoglobin-based oxygen carriers: clinical safety and efficacy of recent and current products. , 2012, Current drug discovery technologies.

[69]  X. Jing,et al.  Polymer/hemoglobin assemblies: biodegradable oxygen carriers for artificial red blood cells. , 2011, Macromolecular bioscience.

[70]  A. Palmer,et al.  Development of a dichloroacetic acid‐hemoglobin conjugate as a potential targeted anti‐cancer therapeutic , 2011, Biotechnology and bioengineering.

[71]  Mostafa H. Ahmed,et al.  Hemoglobin-ligand binding: understanding Hb function and allostery on atomic level. , 2011, Biochimica et biophysica acta.

[72]  T. Chang,et al.  Polyhemoglobin-superoxide Dismutase-catalase-carbonic Anhydrase: A Novel Biotechnology-based Blood Substitute that Transports both Oxygen and Carbon Dioxide and also Acts as an Antioxidant , 2011, Artificial cells, blood substitutes, and immobilization biotechnology.

[73]  J. Briceño,et al.  Perfluorocarbon-based oxygen carriers: review of products and trials. , 2010, Artificial organs.

[74]  H. Horinouchi,et al.  Review of hemoglobin-vesicles as artificial oxygen carriers. , 2009, Artificial organs.

[75]  L. Leybaert,et al.  Water-soluble CO-releasing molecules reduce the development of postoperative ileus via modulation of MAPK/HO-1 signalling and reduction of oxidative stress , 2008, Gut.

[76]  J. Pouysségur,et al.  Hypoxia and cancer , 2007, Journal of Molecular Medicine.

[77]  M. Rousselot,et al.  Arenicola marina extracellular hemoglobin: a new promising blood substitute. , 2006, Biotechnology journal.

[78]  Andre F Palmer,et al.  Polymersome encapsulated hemoglobin: a novel type of oxygen carrier. , 2005, Biomacromolecules.

[79]  Rui Wang,et al.  Continuous inhalation of carbon monoxide attenuates hypoxic pulmonary hypertension development presumably through activation of BKCa channels. , 2005, Cardiovascular research.

[80]  A. Greenburg,et al.  Artificial oxygen carriers as red blood cell substitutes: a selected review and current status. , 2004, Artificial organs.

[81]  T. Chang.  Hemoglobin-based red blood cell substitutes. , 2004, Artificial organs.

[82]  A. Choi,et al.  Low-dose carbon monoxide reduces airway hyperresponsiveness in mice. , 2003, American journal of physiology. Lung cellular and molecular physiology.

[83]  D. Pinsky,et al.  Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis , 2001, Nature Medicine.

[84]  A. Choi,et al.  Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway , 2000, Nature Medicine.

[85]  S. Takeoka,et al.  Synthesis and physicochemical characterization of a series of hemoglobin-based oxygen carriers: objective comparison between cellular and acellular types. , 2000, Bioconjugate chemistry.

[86]  K. Lowe.  Perfluorinated blood substitutes and artificial oxygen carriers. , 1999, Blood reviews.

[87]  K P Offord,et al.  Prognostic significance of histopathologic subsets in idiopathic pulmonary fibrosis. , 1998, American journal of respiratory and critical care medicine.

[88]  M. Paoli,et al.  Crystal structure of T state haemoglobin with oxygen bound at all four haems. , 1996, Journal of molecular biology.

[89]  J. Gutteridge.  Iron promoters of the Fenton reaction and lipid peroxidation can be released from haemoglobin by peroxides , 1986, FEBS letters.