Evaluation of protein C and other biomarkers as predictors of mortality in a rat cecal ligation and puncture model of sepsis*
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R. L. Grubbs | Yun-Fei Chen | J. Jakubowski | B. Grinnell | C. Ding | J. G. Heuer | Tonghai Zhang | D. T. Berg | B. Gerlitz | E. J. Stephens | Ganesh R. Sharma | D. L. Bailey | Douglas Perkins | Kimberly C Holmes | Kelly A Fynboe | D. Berg
[1] R. L. Grubbs,et al. Cecal ligation and puncture with total parenteral nutrition: a clinically relevant model of the metabolic, hormonal, and inflammatory dysfunction associated with critical illness. , 2004, The Journal of surgical research.
[2] T. Iba,et al. [Disseminated intravascular coagulation]. , 2003, Nihon rinsho. Japanese journal of clinical medicine.
[3] R. Dellinger,et al. Inflammation and coagulation: implications for the septic patient. , 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[4] K. Mace,et al. Engineering the proteolytic specificity of activated protein C improves its pharmacological properties , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[5] Mitchell M. Levy,et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference , 2003, Intensive Care Medicine.
[6] R. Hotchkiss,et al. The pathophysiology and treatment of sepsis. , 2003, The New England journal of medicine.
[7] K. Ulm,et al. DIFFERENTIAL REGULATION OF SYSTEMIC IL-18 AND IL-12 RELEASE DURING POSTOPERATIVE SEPSIS: HIGH SERUM IL-18 AS AN EARLY PREDICTIVE INDICATOR OF LETHAL OUTCOME , 2002, Shock.
[8] T. Majima,et al. Role of macrophage inflammatory protein 2 in acute lung injury in murine peritonitis. , 2002, The Journal of surgical research.
[9] J. Helterbrand,et al. Low levels of protein C are associated with poor outcome in severe sepsis. , 2001, Chest.
[10] C. Esmon,et al. Dysfunction of endothelial protein C activation in severe meningococcal sepsis. , 2001, The New England journal of medicine.
[11] G. Clermont,et al. Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care , 2001, Critical care medicine.
[12] J Ean,et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. , 2001, The New England journal of medicine.
[13] C. Fisher,et al. Protein C levels as a prognostic indicator of outcome in sepsis and related diseases , 2000, Critical care medicine.
[14] I. Chaudry,et al. Immune depression in polymicrobial sepsis: The role of necrotic (injured) tissue and endotoxin , 2000, Critical care medicine.
[15] José A Fernández,et al. Prognostic value of protein C concentrations in neutropenic patients at high risk of severe septic complications , 2000, Critical care medicine.
[16] B. Bistrian,et al. Metabolic effects of insulin and insulin-like growth factor-I in endotoxemic rats during total parenteral nutrition feeding. , 2000, Metabolism: clinical and experimental.
[17] R. Balk. SEVERE SEPSIS AND SEPTIC SHOCK Definitions, Epidemiology, and Clinical Manifestations , 2000 .
[18] N. Clausell,et al. Circulating endothelin-1 and tumor necrosis factor-α: early predictors of mortality in patients with septic shock , 2000, Intensive Care Medicine.
[19] S. Deventer,et al. Prognostic value of cytokine concentrations (tumor necrosis factor-alpha, interleukin-6, and interleukin-10) and clinical parameters in severe melioidosis. , 2000, The Journal of infectious diseases.
[20] E. Abraham,et al. Why immunomodulatory therapies have not worked in sepsis , 1999, Intensive Care Medicine.
[21] K. Reinhart,et al. Outcome Prediction by Traditional and New Markers of Inflammation in Patients with Sepsis , 1999, Clinical chemistry and laboratory medicine.
[22] C. Esmon,et al. Plasma levels of endothelial cell protein C receptor are elevated in patients with sepsis and systemic lupus erythematosus: lack of correlation with thrombomodulin suggests involvement of different pathological processes. , 1998, Blood.
[23] K. Shaffer,et al. Radiologic evaluation in lung cancer: diagnosis and staging. , 1997, Chest.
[24] T. Standiford,et al. Elevated levels of macrophage inflammatory protein 2 in severe murine peritonitis increase neutrophil recruitment and mortality , 1997, Infection and immunity.
[25] R. Bone,et al. Sepsis: a new hypothesis for pathogenesis of the disease process. , 1997, Chest.
[26] T. van der Poll,et al. Effect of a recombinant dimeric tumor necrosis factor receptor on inflammatory responses to intravenous endotoxin in normal humans. , 1997, Blood.
[27] M. Lamy,et al. Sepsis and serum cytokine concentrations. , 1997, Critical care medicine.
[28] P. Mannucci,et al. Factor VIIa and antithrombin III activity during severe sepsis and septic shock in neutropenic patients. , 1996, Blood.
[29] S. Alfieri,et al. Prognosis in intra-abdominal infections. Multivariate analysis on 604 patients. , 1996, Archives of surgery.
[30] J. Vincent,et al. Blood lactate levels are better prognostic indicators than TNF and IL-6 levels in patients with septic shock , 1996, Intensive Care Medicine.
[31] R. Auckenthaler,et al. Bedside prediction of mortality from bacteremic sepsis. A dynamic analysis of ICU patients. , 1996, American journal of respiratory and critical care medicine.
[32] S. Nasraway,et al. Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. TNF-alpha MAb Sepsis Study Group. , 1995, JAMA.
[33] G. Koch,et al. Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial , 1995 .
[34] S. Opal,et al. Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome. Results from a randomized, double-blind, placebo-controlled trial. Phase III rhIL-1ra Sepsis Syndrome Study Group. , 1994, JAMA.
[35] R. F. Johnston,et al. Recombinant Human Interleukin 1 Receptor Antagonist in the Treatment of Patients With Sepsis Syndrome: Results From a Randomized, Double-blind, Placebo-Controlled Trial , 1994 .
[36] G Görög,et al. An Excel program for calculating and plotting receiver-operator characteristic (ROC) curves, histograms and descriptive statistics. , 1994, Computers in biology and medicine.
[37] D. Powars,et al. Epidemic meningococcemia and purpura fulminans with induced protein C deficiency. , 1993, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[38] D. Pittet,et al. Importance of pre-existing co-morbidities for prognosis of septicemia in critically ill patients , 1993, Intensive Care Medicine.
[39] M. McManus,et al. Coagulopathy as a predictor of outcome in meningococcal sepsis and the systemic inflammatory response syndrome with purpura , 1993, Critical care medicine.
[40] J. Lorente,et al. clinical investigations in critical care Time Course of Hemostatic Abnormalities in Sepsis and its Relation to Outcome * , 2006 .
[41] C. Chopin,et al. Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies. , 1992, Chest.
[42] M. Blombäck,et al. Protein C, Protein S and c4b-Binding Protein in Severe lnfection and Septic Shock , 1991, Thrombosis and Haemostasis.
[43] F. Cerra,et al. Multiple organ failure syndrome. , 1990, Disease-a-month : DM.
[44] M. Nettleman,et al. Receiver Operator Characteristic (ROC) Curves , 1988, Infection Control & Hospital Epidemiology.
[45] Christine M. Miller,et al. Serial Studies of Protein C and Its Plasma Inhibitor in Patients With , 1985 .
[46] K. Kario,et al. Fibrin D-dimer in thrombogenic disorders. , 2000, Seminars in thrombosis and hemostasis.
[47] T. Koyama,et al. Plasma Levels of Endothelial Cell Protein C Receptor Are Elevated in Patients With Sepsis and Systemic Lupus Erythematosus : Lack of Correlation With Thrombomodulin Suggests Involvement of Different Pathological Processes , 1998 .
[48] J. T. ten Cate,et al. Coagulation Activation and Tissue Necrosis in Meningococcal Septic Shock: Severely Reduced Protein C Levels Predict a High Mortality , 1995, Thrombosis and Haemostasis.
[49] J. Román,et al. Protein C, protein S and C4b-binding protein in neonatal severe infection and septic shock , 1992, Journal of perinatal medicine.