Gene fusion characterisation of rare aggressive prostate cancer variants—adenosquamous carcinoma, pleomorphic giant‐cell carcinoma, and sarcomatoid carcinoma: an analysis of 19 cases

To evaluate the molecular underpinnings of the rare aggressive prostate cancer variants adenosquamous carcinoma, pleomorphic giant‐cell carcinoma, and sarcomatoid carcinoma.

[1]  Siraj M. Ali,et al.  Squamous Transformation of Prostate Adenocarcinoma: A Report of Two Cases With Genomic Profiling. , 2019, Clinical genitourinary cancer.

[2]  Yi Mi Wu,et al.  Genomic correlates of clinical outcome in advanced prostate cancer , 2019, Proceedings of the National Academy of Sciences.

[3]  J. Epstein,et al.  DNA damage repair alterations are frequent in prostatic adenocarcinomas with focal pleomorphic giant‐cell features , 2019, Histopathology.

[4]  Xiaobo Zhou,et al.  FusionGDB: fusion gene annotation DataBase , 2018, Nucleic Acids Res..

[5]  J. Hicks,et al.  Prostatic Adenocarcinoma With Focal Pleomorphic Giant Cell Features: A Series of 30 Cases , 2018, The American journal of surgical pathology.

[6]  K. Perry,et al.  Pseudosarcomatous myofibroblastic proliferations of the genitourinary tract are genetically different from nodular fasciitis and lack USP6, ROS1 and ETV6 gene rearrangements , 2018, Histopathology.

[7]  Li Ding,et al.  Driver Fusions and Their Implications in the Development and Treatment of Human Cancers , 2018, Cell reports.

[8]  M. Pajic,et al.  BRAF gene rearrangements can be identified by FISH studies in pancreatic acinar cell carcinoma. , 2018, Pathology.

[9]  J. Carroll,et al.  Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer. , 2017, Cancer research.

[10]  Zachary J. Heins,et al.  Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making. , 2017, JCO precision oncology.

[11]  Kai Wang,et al.  The distribution of BRAF gene fusions in solid tumors and response to targeted therapy , 2015, International journal of cancer.

[12]  Arul M. Chinnaiyan,et al.  Landscape of gene fusions in epithelial cancers: seq and ye shall find , 2015, Genome Medicine.

[13]  Y. Asmann,et al.  Common Oncogene Mutations and Novel SND1-BRAF Transcript Fusion in Lung Adenocarcinoma from Never Smokers , 2015, Scientific Reports.

[14]  S. Hazell,et al.  Sarcomatoid carcinoma of the prostate: ERG fluorescence in‐situ hybridization confirms epithelial origin , 2015, Histopathology.

[15]  Lawrence D. True,et al.  Integrative Clinical Genomics of Advanced Prostate Cancer , 2015, Cell.

[16]  J. Biegel,et al.  Chromosome Band 7q34 Deletions Resulting in KIAA1549‐BRAF and FAM131B‐BRAF Fusions in Pediatric Low‐Grade Gliomas , 2015, Brain pathology.

[17]  L. Wood,et al.  Pathology and genetics of pancreatic neoplasms with acinar differentiation. , 2014, Seminars in diagnostic pathology.

[18]  P. Stephens,et al.  Comprehensive genomic profiling of pancreatic acinar cell carcinomas identifies recurrent RAF fusions and frequent inactivation of DNA repair genes. , 2014, Cancer discovery.

[19]  A. Sivachenko,et al.  Punctuated Evolution of Prostate Cancer Genomes , 2013, Cell.

[20]  M. Rubin,et al.  Novel Dual Color Immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma , 2013, Modern Pathology.

[21]  C. Magi-Galluzzi,et al.  ERG protein expression in human tumors detected with a rabbit monoclonal antibody. , 2012, American journal of clinical pathology.

[22]  David T. W. Jones,et al.  Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma , 2011, Acta Neuropathologica.

[23]  Francesca Demichelis,et al.  Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma , 2010, Nature Medicine.

[24]  A. Lopez‐Beltran,et al.  Rare and unusual histological variants of prostatic carcinoma: clinical significance , 2008, BJU international.

[25]  A. Parwani,et al.  Pleomorphic Giant Cell Adenocarcinoma of the Prostate: Report of 6 Cases , 2006, The American journal of surgical pathology.

[26]  R. Shah,et al.  Clonality of sarcomatous and carcinomatous elements in sarcomatoid carcinoma of the prostate. , 2006, Urology.

[27]  A. Parwani,et al.  Prostate Carcinoma With Squamous Differentiation: An Analysis of 33 Cases , 2004, The American journal of surgical pathology.

[28]  D. Grignon Unusual subtypes of prostate cancer , 2004, Modern Pathology.