Heat shock proteins: Cellular and molecular mechanisms in the central nervous system

[1]  David L. Thomas,et al.  Overexpression of Heat Shock Protein 27 Reduces Cortical Damage after Cerebral Ischemia , 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[2]  Carol D. Hicks,et al.  Brain-Permeable Small-Molecule Inhibitors of Hsp90 Prevent α-Synuclein Oligomer Formation and Rescue α-Synuclein-Induced Toxicity , 2010, Journal of Pharmacology and Experimental Therapeutics.

[3]  H. Kampinga,et al.  A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation. , 2010, Molecular cell.

[4]  R. Raghubir,et al.  Endoplasmic Reticulum Stress Plays Critical Role in Brain Damage After Cerebral Ischemia/Reperfusion in Rats , 2010, Neurotoxicity Research.

[5]  Sanjeev Gupta,et al.  Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response , 2010, International journal of cell biology.

[6]  J. Shorter,et al.  Applying Hsp104 to protein-misfolding disorders. , 2010, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[7]  Lawrence Rajendran,et al.  The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids , 2009, Neuron.

[8]  K. Mearow,et al.  The small heat shock protein Hsp27 protects cortical neurons against the toxic effects of β‐amyloid peptide , 2009, Journal of neuroscience research.

[9]  T. Tatsuta Protein quality control in mitochondria. , 2009, Journal of biochemistry.

[10]  Z. Mao,et al.  The complexity in regulation of MEF2D by chaperone-mediated autophagy , 2009, Autophagy.

[11]  Youhei Saito,et al.  Hsp105β upregulates hsp70 gene expression through signal transducer and activator of transcription‐3 , 2009, The FEBS journal.

[12]  E. Weeber,et al.  Chemical Manipulation of Hsp70 ATPase Activity Regulates Tau Stability , 2009, The Journal of Neuroscience.

[13]  D. Green,et al.  Characterization of cytoplasmic caspase-2 activation by induced proximity. , 2009, Molecular cell.

[14]  M. Mena,et al.  Parkin deficiency increases the resistance of midbrain neurons and glia to mild proteasome inhibition: the role of autophagy and glutathione homeostasis , 2009, Journal of neurochemistry.

[15]  Jianhe Peng,et al.  Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function , 2009, Proteomics.

[16]  Jun Chen,et al.  HSP27: mechanisms of cellular protection against neuronal injury. , 2009, Current molecular medicine.

[17]  Shihua Li,et al.  Activation of Gene Transcription by Heat Shock Protein 27 May Contribute to Its Neuronal Protection* , 2009, The Journal of Biological Chemistry.

[18]  Davide Pareyson,et al.  Diagnosis, natural history, and management of Charcot–Marie–Tooth disease , 2009, The Lancet Neurology.

[19]  J. Meldolesi,et al.  The surface‐exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor , 2009, Journal of neurochemistry.

[20]  R. Leak,et al.  The molecular chaperone Hsc70 interacts with the vesicular monoamine transporter‐2 , 2009, Journal of neurochemistry.

[21]  H. Braak,et al.  Parkinson's Disease , 2009, Annals of the New York Academy of Sciences.

[22]  Michael Cascio,et al.  Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells , 2009, Neurobiology of Disease.

[23]  J. Castilla,et al.  In Vivo Generation of Neurotoxic Prion Protein: Role for Hsp70 in Accumulation of Misfolded Isoforms , 2009, PLoS genetics.

[24]  Jingzhi Li,et al.  Heat shock protein 40: structural studies and their functional implications. , 2009, Protein and peptide letters.

[25]  R. Perez,et al.  14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: localization of dopamine regulatory proteins to mitochondria. , 2009, The Journal of biological chemistry.

[26]  David Park,et al.  Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy , 2009, PloS one.

[27]  I. Regidor,et al.  Expression of heat shock protein 90 at the cell surface in human neuroblastoma cells , 2009, Cell Stress and Chaperones.

[28]  Robin L. Anderson,et al.  Hsp72 chaperone function is dispensable for protection against stress-induced apoptosis , 2009, Cell Stress and Chaperones.

[29]  P. Graceffa,et al.  Phosphorylation Dependence of Hsp27 Multimeric Size and Molecular Chaperone Function* , 2009, The Journal of Biological Chemistry.

[30]  L. Tönges,et al.  TAT-Hsp70-Mediated Neuroprotection and Increased Survival of Neuronal Precursor Cells after Focal Cerebral Ischemia in Mice , 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[31]  Lalita A. Shevde,et al.  Multi-faceted role of HSP40 in cancer , 2009, Clinical & Experimental Metastasis.

[32]  B. Kamińska,et al.  Molecular Mechanisms Leading to Neuroprotection/Ischemic Tolerance: Effect of Preconditioning on the Stress Reaction of Endoplasmic Reticulum , 2009, Cellular and Molecular Neurobiology.

[33]  B. Kamińska,et al.  Molecular Analysis of Endoplasmic Reticulum Stress Response After Global Forebrain Ischemia/Reperfusion in Rats: Effect of Neuroprotectant Simvastatin , 2009, Cellular and Molecular Neurobiology.

[34]  F. Hartl,et al.  Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3 , 2009, The EMBO journal.

[35]  G. Buonocore,et al.  Autophagy in hypoxia-ischemia induced brain injury: Evidences and speculations , 2009, Autophagy.

[36]  R. Beyer,et al.  Rab11a and HSP90 Regulate Recycling of Extracellular α-Synuclein , 2009, The Journal of Neuroscience.

[37]  David L. Thomas,et al.  Protective Effect of Post-Ischaemic Viral Delivery of Heat Shock Proteins in vivo , 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[38]  R. Giffard,et al.  Overexpression of Mitochondrial Hsp70/Hsp75 in Rat Brain Protects Mitochondria, Reduces Oxidative Stress, and Protects from Focal Ischemia , 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[39]  S. Yen,et al.  Proteomic profiling of phosphoproteins and glycoproteins responsive to wild-type alpha-synuclein accumulation and aggregation. , 2009, Biochimica et biophysica acta.

[40]  Bingren Hu,et al.  Subcellular stress response and induction of molecular chaperones and folding proteins after transient global ischemia in rats , 2009, Brain Research.

[41]  M. Gearing,et al.  Regulation of Neuronal Survival Factor MEF2D by Chaperone-Mediated Autophagy , 2009, Science.

[42]  G. R. Prescott,et al.  Phosphorylation of cysteine string protein on Serine 10 triggers 14-3-3 protein binding. , 2008, Biochemical and biophysical research communications.

[43]  Feng Zhang,et al.  Hsp27 Protects against Ischemic Brain Injury via Attenuation of a Novel Stress-Response Cascade Upstream of Mitochondrial Cell Death Signaling , 2008, The Journal of Neuroscience.

[44]  G. Buonocore,et al.  Protective role of autophagy in neonatal hypoxia–ischemia induced brain injury , 2008, Neurobiology of Disease.

[45]  J. Linnoila,et al.  A Mammalian Homolog of Drosophila Tumorous Imaginal Discs, Tid1, Mediates Agrin Signaling at the Neuromuscular Junction , 2008, Neuron.

[46]  J. Trojanowski,et al.  Interactions between Hsp70 and the hydrophobic core of alpha-synuclein inhibit fibril assembly. , 2008, Biochemistry.

[47]  Youhei Saito,et al.  Nuclear localization mechanism of Hsp105beta and its possible function in mammalian cells. , 2008, Journal of biochemistry.

[48]  Timothy Y. Huang,et al.  Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation. , 2008, Developmental cell.

[49]  Jun Chen,et al.  Rapidly Increased Neuronal Mitochondrial Biogenesis After Hypoxic-Ischemic Brain Injury , 2008, Stroke.

[50]  B. Blagg,et al.  Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket. , 2008, Current medicinal chemistry.

[51]  J. Fiaux,et al.  Insights into the structural dynamics of the Hsp110–Hsp70 interaction reveal the mechanism for nucleotide exchange activity , 2008, Proceedings of the National Academy of Sciences.

[52]  J. Koren,et al.  Chaperone signalling complexes in Alzheimer's disease , 2008, Journal of cellular and molecular medicine.

[53]  Xiang-ru Wen,et al.  Dual inhibitory roles of geldanamycin on the c-Jun NH2-terminal kinase 3 signal pathway through suppressing the expression of mixed-lineage kinase 3 and attenuating the activation of apoptosis signal-regulating kinase 1 via facilitating the activation of Akt in ischemic brain injury , 2008, Neuroscience.

[54]  Andrew D. Steele,et al.  Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease , 2008, Proceedings of the National Academy of Sciences.

[55]  S. Lindquist,et al.  Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease. , 2008, The Journal of clinical investigation.

[56]  Kostas Vekrellis,et al.  Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells* , 2008, Journal of Biological Chemistry.

[57]  M. Xilouri,et al.  Alpha-synuclein degradation by autophagic pathways: A potential key to Parkinson’s Disease pathogenesis , 2008, Autophagy.

[58]  A. Cuervo,et al.  The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane , 2008, Molecular and Cellular Biology.

[59]  J. Buchner,et al.  The Hsp90 Chaperone Machinery* , 2008, Journal of Biological Chemistry.

[60]  Jill T. Jamison,et al.  Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion , 2008, Neuroscience.

[61]  Feng Qi Han,et al.  Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways , 2008, Autophagy.

[62]  E. Barrón,et al.  The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells , 2008, Cell Death and Differentiation.

[63]  Radhey S. Gupta,et al.  Unusual cellular disposition of the mitochondrial molecular chaperones Hsp60, Hsp70 and Hsp10. , 2008, Novartis Foundation symposium.

[64]  W. Boelens,et al.  Expression of the small heat shock protein family in the mouse CNS: Differential anatomical and biochemical compartmentalization , 2008, Neuroscience.

[65]  Shiuan Wey,et al.  Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP , 2008, PloS one.

[66]  J. Emery,et al.  Overexpression of Mitochondrial Hsp70/Hsp75 Protects Astrocytes against Ischemic Injury in vitro , 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[67]  A. Cuervo,et al.  Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy. , 2008, Molecular biology of the cell.

[68]  X. Zhao,et al.  Biological Roles of Neural J Proteins , 2008, Cellular and Molecular Life Sciences.

[69]  B. Freeman,et al.  HSP90: The Rosetta stone for cellular protein dynamics? , 2008, Cell cycle.

[70]  A. Chang,et al.  Heat shock response relieves ER stress , 2008, The EMBO journal.

[71]  Jocelyne Fiaux,et al.  Hsp110 Is a Nucleotide-activated Exchange Factor for Hsp70* , 2008, Journal of Biological Chemistry.

[72]  H. Cai,et al.  The Chaperone Activity of Heat Shock Protein 90 Is Critical for Maintaining the Stability of Leucine-Rich Repeat Kinase 2 , 2008, The Journal of Neuroscience.

[73]  L. Petrucelli,et al.  Akt and CHIP coregulate tau degradation through coordinated interactions , 2008, Proceedings of the National Academy of Sciences.

[74]  M. Cascio,et al.  Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: Implications for Parkinson disease , 2008, Neurobiology of Disease.

[75]  S. Kim,et al.  Transduced human PEP‐1–heat shock protein 27 efficiently protects against brain ischemic insult , 2008, The FEBS journal.

[76]  Z. Qin,et al.  An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid , 2008, Autophagy.

[77]  Yan Wang,et al.  Mortalin: A Protein Associated With Progression of Parkinson Disease? , 2008, Journal of neuropathology and experimental neurology.

[78]  Peter T Lansbury,et al.  Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy. , 2008, The Journal of clinical investigation.

[79]  J. Landry,et al.  HspB8 and Bag3: A new chaperone complex targeting misfolded proteins to macroautophagy , 2008, Autophagy.

[80]  Tingting Yang,et al.  Heat shock protein 70 expression in epilepsy suggests stress rather than protection , 2008, Acta Neuropathologica.

[81]  J. Landry,et al.  HspB8 Chaperone Activity toward Poly(Q)-containing Proteins Depends on Its Association with Bag3, a Stimulator of Macroautophagy* , 2008, Journal of Biological Chemistry.

[82]  Bingren Hu,et al.  Protein Aggregation and Proteasome Dysfunction After Brain Ischemia , 2007, Stroke.

[83]  K. Yoo,et al.  Changes in immunoreactivity of HSP60 and its neuroprotective effects in the gerbil hippocampal CA1 region induced by transient ischemia , 2007, Experimental Neurology.

[84]  D. DeGracia,et al.  Hippocampal cellular stress responses after global brain ischemia and reperfusion. , 2007, Antioxidants & redox signaling.

[85]  N. Gusev,et al.  Effect of mutations in the β5–β7 loop on the structure and properties of human small heat shock protein HSP22 (HspB8, H11) , 2007 .

[86]  N. Chebotareva,et al.  Small heat shock protein Hsp27 prevents heat‐induced aggregation of F‐actin by forming soluble complexes with denatured actin , 2007, The FEBS journal.

[87]  Youhei Saito,et al.  Different localization of Hsp105 family proteins in mammalian cells. , 2007, Experimental cell research.

[88]  S. Simon,et al.  HSP60 in heart failure: abnormal distribution and role in cardiac myocyte apoptosis. , 2007, American Journal of Physiology. Heart and Circulatory Physiology.

[89]  Andrew D. Steele,et al.  Prion Pathogenesis is Independent of Caspase-12 , 2007, Prion.

[90]  L. Hinrichsen,et al.  Endocytosis: clathrin-mediated membrane budding. , 2007, Current opinion in cell biology.

[91]  Y. Oida,et al.  Involvement of endoplasmic reticulum stress after middle cerebral artery occlusion in mice , 2007, Neuroscience.

[92]  M. Merchant,et al.  Hsp27 Regulates Akt Activation and Polymorphonuclear Leukocyte Apoptosis by Scaffolding MK2 to Akt Signal Complex* , 2007, Journal of Biological Chemistry.

[93]  E. Eisenberg,et al.  Multiple Roles of Auxilin and Hsc70 in Clathrin‐Mediated Endocytosis , 2007, Traffic.

[94]  G. Xiao,et al.  Hsp90 regulates processing of NF-κB2 p100 involving protection of NF-κB-inducing kinase (NIK) from autophagy-mediated degradation , 2007, Cell Research.

[95]  E. Wanker,et al.  Small Molecule Inducers of Heat-Shock Response Reduce polyQ-Mediated Huntingtin Aggregation , 2007, Neurodegenerative Diseases.

[96]  Paul Greengard,et al.  Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies , 2007, Proceedings of the National Academy of Sciences.

[97]  Xun Shen,et al.  Heat Shock Protein 27 Protects L929 Cells from Cisplatin-Induced Apoptosis by Enhancing Akt Activation and Abating Suppression of Thioredoxin Reductase Activity , 2007, Clinical Cancer Research.

[98]  N. Déglon,et al.  Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease. , 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

[99]  S. Tabrizi,et al.  Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation. , 2007, Human molecular genetics.

[100]  J. Cross,et al.  The Mrj co-chaperone mediates keratin turnover and prevents the formation of toxic inclusion bodies in trophoblast cells of the placenta , 2007, Development.

[101]  Ja-Kyeong Lee,et al.  NO‐induced downregulation of HSP10 and HSP60 expression in the postischemic brain , 2007, Journal of neuroscience research.

[102]  H. Bramlett,et al.  Subcellular stress response after traumatic brain injury. , 2007, Journal of neurotrauma.

[103]  Toshiharu Suzuki,et al.  Endoplasmic reticulum chaperones inhibit the production of amyloid-β peptides , 2007 .

[104]  M. Jäättelä,et al.  Lens epithelium-derived growth factor is an Hsp70-2 regulated guardian of lysosomal stability in human cancer. , 2007, Cancer research.

[105]  Cam Patterson,et al.  The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins. , 2007, The Journal of clinical investigation.

[106]  S. Salim,et al.  Role of 90-kDa Heat Shock Protein (Hsp 90) and Protein Degradation in Regulating Neuronal Levels of G Protein-Coupled Receptor Kinase 3 , 2007, Journal of Pharmacology and Experimental Therapeutics.

[107]  N. Nakamura,et al.  Knockdown of Mitochondrial Heat Shock Protein 70 Promotes Progeria-like Phenotypes in Caenorhabditis elegans* , 2007, Journal of Biological Chemistry.

[108]  N. Rosen,et al.  An acetylation site in the middle domain of Hsp90 regulates chaperone function. , 2007, Molecular cell.

[109]  B. Hyman,et al.  Small Heat Shock Proteins Protect Against α-Synuclein-Induced Toxicity and Aggregation , 2006 .

[110]  Hui Zhou,et al.  Heat shock protein 70 inhibits alpha-synuclein fibril formation via interactions with diverse intermediates. , 2006, Journal of molecular biology.

[111]  Srimoyee Ghosh,et al.  A Drosophila ortholog of the human MRJ modulates polyglutamine toxicity and aggregation , 2006, Neurobiology of Disease.

[112]  J. Greaves,et al.  Dual role of the cysteine-string domain in membrane binding and palmitoylation-dependent sorting of the molecular chaperone cysteine-string protein. , 2006, Molecular biology of the cell.

[113]  M. Yano,et al.  A novel function of 14-3-3 protein: 14-3-3zeta is a heat-shock-related molecular chaperone that dissolves thermal-aggregated proteins. , 2006, Molecular biology of the cell.

[114]  P. Coffino,et al.  The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome system. , 2006, Molecular biology of the cell.

[115]  S. Simon,et al.  Abnormal small heat shock protein interactions involving neuropathy‐associated HSP22 (HSPB8) mutants , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[116]  N. Gusev,et al.  Structure and properties of K141E mutant of small heat shock protein HSP22 (HspB8, H11) that is expressed in human neuromuscular disorders. , 2006, Archives of biochemistry and biophysics.

[117]  S. Miao,et al.  The diversity of the DnaJ/Hsp40 family, the crucial partners for Hsp70 chaperones , 2006, Cellular and Molecular Life Sciences CMLS.

[118]  E. Eisenberg,et al.  Recruitment dynamics of GAK and auxilin to clathrin-coated pits during endocytosis , 2006, Journal of Cell Science.

[119]  T. Good,et al.  Small heat shock proteins differentially affect Abeta aggregation and toxicity. , 2006, Biochemical and biophysical research communications.

[120]  J. Kay,et al.  Rdj2, a J protein family member, interacts with cellular prion PrP(C). , 2006, Biochemical and biophysical research communications.

[121]  T. Bartke,et al.  Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP. , 2006, Molecular biology of the cell.

[122]  S. Wisniewski,et al.  Mitochondrial Heat Shock Protein 60 Is Increased in Cerebrospinal Fluid following Pediatric Traumatic Brain Injury , 2006, Developmental Neuroscience.

[123]  Yan Wang,et al.  Proteomic Identification of a Stress Protein, Mortalin/mthsp70/GRP75 , 2006, Molecular & Cellular Proteomics.

[124]  Lijun Xu,et al.  The Carboxyl-Terminal Domain of Inducible Hsp70 Protects from Ischemic Injury in vivo and in vitro , 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[125]  Bernd Bukau,et al.  Chaperone network in the yeast cytosol: Hsp110 is revealed as an Hsp70 nucleotide exchange factor , 2006, The EMBO journal.

[126]  Andreas Bracher,et al.  Molecular chaperones of the Hsp110 family act as nucleotide exchange factors of Hsp70s , 2006, The EMBO journal.

[127]  L. Pearl,et al.  Structure and mechanism of the Hsp90 molecular chaperone machinery. , 2006, Annual review of biochemistry.

[128]  Irene Otte-Höller,et al.  Small heat shock proteins inhibit amyloid-β protein aggregation and cerebrovascular amyloid-β protein toxicity , 2006, Brain Research.

[129]  J. N. Spelbrink,et al.  Tid1 Isoforms Are Mitochondrial DnaJ-like Chaperones with Unique Carboxyl Termini That Determine Cytosolic Fate* , 2006, Journal of Biological Chemistry.

[130]  A. Cuervo,et al.  Consequences of the selective blockage of chaperone-mediated autophagy. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[131]  P. Wesseling,et al.  Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains , 2006, Neuropathology and applied neurobiology.

[132]  L. Petrucelli,et al.  HSP induction mediates selective clearance of tau phosphorylated at proline‐directed Ser/Thr sites but not KXGS (MARK) sites , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[133]  Romana Höftberger,et al.  Endoplasmic Reticulum Stress Features Are Prominent in Alzheimer Disease but Not in Prion Diseases In Vivo , 2006, Journal of neuropathology and experimental neurology.

[134]  J. Frydman,et al.  Chaperonin GroEL and its mutant D87K protect from ischemia in vivo and in vitro , 2006, Neurobiology of Aging.

[135]  Zhiyong Wang,et al.  Distinct hsp70 Domains Mediate Apoptosis-inducing Factor Release and Nuclear Accumulation* , 2006, Journal of Biological Chemistry.

[136]  T. Nabeshima,et al.  An Analog of a Dipeptide-Like Structure of FK506 Increases Glial Cell Line-Derived Neurotrophic Factor Expression through cAMP Response Element-Binding Protein Activated by Heat Shock Protein 90/Akt Signaling Pathway , 2006, The Journal of Neuroscience.

[137]  John Q. Trojanowski,et al.  Convergence of Heat Shock Protein 90 with Ubiquitin in Filamentous α-Synuclein Inclusions of α-Synucleinopathies , 2006 .

[138]  David L. Thomas,et al.  Neuroprotective Effects of Virally Delivered HSPs in Experimental Stroke , 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[139]  M. Verbeek,et al.  Small heat shock protein HspB8: its distribution in Alzheimer’s disease brains and its inhibition of amyloid-β protein aggregation and cerebrovascular amyloid-β toxicity , 2006, Acta Neuropathologica.

[140]  D. Ferriero,et al.  Reduction of caspase-8 and -9 cleavage is associated with increased c-FLIP and increased binding of Apaf-1 and Hsp70 after neonatal hypoxic/ischemic injury in mice overexpressing Hsp70. , 2006, Stroke.

[141]  J. Buchner,et al.  The phosphatase Ppt1 is a dedicated regulator of the molecular chaperone Hsp90 , 2006, The EMBO journal.

[142]  K. Davies,et al.  A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes. , 2006, Human molecular genetics.

[143]  B. Hu,et al.  Co-translational protein aggregation after transient cerebral ischemia , 2005, Neuroscience.

[144]  Viviane Poupon,et al.  The DnaJ-domain Protein RME-8 Functions in Endosomal Trafficking* , 2005, Journal of Biological Chemistry.

[145]  Yumei Wang,et al.  Geldanamycin Induces Heat Shock Protein 70 and Protects against MPTP-induced Dopaminergic Neurotoxicity in Mice* , 2005, Journal of Biological Chemistry.

[146]  W. Houry,et al.  Hsp90: a chaperone for protein folding and gene regulation. , 2005, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[147]  D. D. Mosser,et al.  Hsp70 Inhibits Heat-induced Apoptosis Upstream of Mitochondria by Preventing Bax Translocation* , 2005, Journal of Biological Chemistry.

[148]  K. Ashe,et al.  Age-Dependent Neurofibrillary Tangle Formation, Neuron Loss, and Memory Impairment in a Mouse Model of Human Tauopathy (P301L) , 2005, The Journal of Neuroscience.

[149]  Thomas C. Südhof,et al.  α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration , 2005, Cell.

[150]  W. D. de Jong,et al.  Nuclear Import of αB-crystallin Is Phosphorylation-dependent and Hampered by Hyperphosphorylation of the Myopathy-related Mutant R120G* , 2005, Journal of Biological Chemistry.

[151]  W. Nastainczyk,et al.  BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP. , 2005, Molecular biology of the cell.

[152]  J. Satoh,et al.  The 14-3-3 Protein Forms a Molecular Complex with Heat Shock Protein Hsp60 and Cellular Prion Protein , 2005, Journal of neuropathology and experimental neurology.

[153]  J. Gurd,et al.  Association of heat shock proteins and neuronal membrane components with lipid rafts from the rat brain , 2005, Journal of neuroscience research.

[154]  S. Mandel,et al.  Gene Expression Profiling of Sporadic Parkinson's Disease Substantia Nigra Pars Compacta Reveals Impairment of Ubiquitin‐Proteasome Subunits, SKP1A, Aldehyde Dehydrogenase, and Chaperone HSC‐70 , 2005, Annals of the New York Academy of Sciences.

[155]  P. Finn,et al.  Effects of Small Molecules on Chaperone-Mediated Autophagy , 2005, Autophagy.

[156]  D. Ferriero,et al.  Hsp70 Overexpression Sequesters AIF and Reduces Neonatal Hypoxic/Ischemic Brain Injury , 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[157]  J. Landry,et al.  HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells. , 2005, Human molecular genetics.

[158]  M. Cheetham,et al.  HSJ1 Is a Neuronal Shuttling Factor for the Sorting of Chaperone Clients to the Proteasome , 2005, Current Biology.

[159]  Hui-yu Liu,et al.  Human Tumorous Imaginal Disc 1 (TID1) Associates with Trk Receptor Tyrosine Kinases and Regulates Neurite Outgrowth in nnr5-TrkA Cells* , 2005, Journal of Biological Chemistry.

[160]  C. Dobson,et al.  Heat Shock Protein 70 Inhibits α-Synuclein Fibril Formation via Preferential Binding to Prefibrillar Species* , 2005, Journal of Biological Chemistry.

[161]  Peter Hinterdorfer,et al.  Detection of HSP60 on the membrane surface of stressed human endothelial cells by atomic force and confocal microscopy , 2005, Journal of Cell Science.

[162]  Ann-Shyn Chiang,et al.  Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[163]  T. Good,et al.  Hsp20, a novel α‐crystallin, prevents Aβ fibril formation and toxicity , 2005, Protein science : a publication of the Protein Society.

[164]  Jennifer Lippincott-Schwartz,et al.  Stable Binding of ATF6 to BiP in the Endoplasmic Reticulum Stress Response , 2005, Molecular and Cellular Biology.

[165]  P. Auluck,et al.  Mechanisms of Suppression of α-Synuclein Neurotoxicity by Geldanamycin in Drosophila* , 2005, Journal of Biological Chemistry.

[166]  J. Dice,et al.  Mechanisms of chaperone-mediated autophagy. , 2004, The international journal of biochemistry & cell biology.

[167]  S. Alberti,et al.  Cooperation of molecular chaperones with the ubiquitin/proteasome system. , 2004, Biochimica et biophysica acta.

[168]  A. Cuervo,et al.  Activation of chaperone-mediated autophagy during oxidative stress. , 2004, Molecular biology of the cell.

[169]  E. Craig,et al.  Regulated interactions of mtHsp70 with Tim44 at the translocon in the mitochondrial inner membrane , 2004, Nature Structural &Molecular Biology.

[170]  G. Panayotou,et al.  Involvement of Cell Surface HSP90 in Cell Migration Reveals a Novel Role in the Developing Nervous System* , 2004, Journal of Biological Chemistry.

[171]  N. Yamagishi,et al.  Hsp105α Suppresses Hsc70 Chaperone Activity by Inhibiting Hsc70 ATPase Activity* , 2004, Journal of Biological Chemistry.

[172]  S. Alberti,et al.  The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator. , 2004, Molecular biology of the cell.

[173]  B. Hyman,et al.  Geldanamycin induces Hsp70 and prevents α-synuclein aggregation and toxicity in vitro , 2004 .

[174]  B. Devreese,et al.  Cross‐linking of ubiquitin, HSP27, parkin and α‐synuclein by γ‐glutamyl‐ε‐lysine bonds in Alzheimer's neurofibrillary tangles , 2004 .

[175]  G. Bates,et al.  Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach. , 2004, Human molecular genetics.

[176]  Jochen Klucken,et al.  Hsp70 Reduces α-Synuclein Aggregation and Toxicity* , 2004, Journal of Biological Chemistry.

[177]  W. Robberecht,et al.  Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy , 2004, Nature Genetics.

[178]  Kenneth S. Kosik,et al.  Binding of Tau to Heat Shock Protein 27 Leads to Decreased Concentration of Hyperphosphorylated Tau and Enhanced Cell Survival* , 2004, Journal of Biological Chemistry.

[179]  T. Südhof,et al.  The Synaptic Vesicle Protein CSPα Prevents Presynaptic Degeneration , 2004, Neuron.

[180]  S. Oyadomari,et al.  hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria , 2004, Cell Death and Differentiation.

[181]  R. Minchin,et al.  Interaction of the Hsp90 cochaperone cyclophilin 40 with Hsc70 , 2004, Cell stress & chaperones.

[182]  P. Csermely,et al.  Hsp90 isoforms: functions, expression and clinical importance , 2004, FEBS letters.

[183]  K. Walsh,et al.  Heat Shock Protein 70 Participates in the Neuroprotective Response to Intracellularly Expressed β-Amyloid in Neurons , 2004, The Journal of Neuroscience.

[184]  W. Paschen,et al.  Brain trauma induces X‐box protein 1 processing indicative of activation of the endoplasmic reticulum unfolded protein response , 2004, Journal of neurochemistry.

[185]  A. Alcázar,et al.  Antibodies reactive to heat shock protein 90 induce oligodendrocyte precursor cell death in culture. Implications for demyelination in multiple sclerosis , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[186]  P. Weinstein,et al.  Overexpression of Rat Heat Shock Protein 70 Reduces Neuronal Injury after Transient Focal Ischemia, Transient Global Ischemia, or Kainic Acid-induced Seizures , 2003, Neurosurgery.

[187]  J. Castilla,et al.  Caspase‐12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein , 2003, The EMBO journal.

[188]  G. Kroemer,et al.  Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor , 2003, Oncogene.

[189]  E. Tolosa,et al.  Clinical overview of the synucleinopathies , 2003, Movement disorders : official journal of the Movement Disorder Society.

[190]  J. Klein,et al.  Heat Shock Protein 27 Controls Apoptosis by Regulating Akt Activation* , 2003, Journal of Biological Chemistry.

[191]  S. Kiryu-Seo,et al.  Expression of the Activating Transcription Factor 3 Prevents c-Jun N-Terminal Kinase-Induced Neuronal Death by Promoting Heat Shock Protein 27 Expression and Akt Activation , 2003, The Journal of Neuroscience.

[192]  P. Weinstein,et al.  Overexpression of Rat Heat Shock Protein 70 is Associated with Reduction of Early Mitochondrial Cytochrome c Release and Subsequent DNA Fragmentation after Permanent Focal Ischemia , 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[193]  M. Akbar,et al.  The Neuroprotective Effects of Heat Shock Protein 27 Overexpression in Transgenic Animals against Kainate-induced Seizures and Hippocampal Cell Death* , 2003, Journal of Biological Chemistry.

[194]  M. Akbar,et al.  Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss. , 2003, Brain research. Molecular brain research.

[195]  Jianning Wei,et al.  Demonstration of functional coupling between γ-aminobutyric acid (GABA) synthesis and vesicular GABA transport into synaptic vesicles , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[196]  W. Pratt,et al.  Regulation of Signaling Protein Function and Trafficking by the hsp90/hsp70-Based Chaperone Machinery 1 , 2003, Experimental biology and medicine.

[197]  Akihiko Takashima,et al.  Chaperones increase association of tau protein with microtubules , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[198]  N. Bonini Chaperoning brain degeneration , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[199]  L. Neckers,et al.  Heat Shock Protein 90 Modulates the Unfolded Protein Response by Stabilizing IRE1α , 2002, Molecular and Cellular Biology.

[200]  S. Gupta,et al.  Cytosolic Heat Shock Protein 60, Hypoxia, and Apoptosis , 2002, Circulation.

[201]  Sunghoon Kim,et al.  Heat Shock Protein Hsp72 Is a Negative Regulator of Apoptosis Signal-Regulating Kinase 1 , 2002, Molecular and Cellular Biology.

[202]  M. Rahimtula,et al.  Stress‐mediated signaling in PC12 cells – the role of the small heat shock protein, Hsp27, and Akt in protecting cells from heat stress and nerve growth factor withdrawal , 2002, Journal of neurochemistry.

[203]  K. Liberek,et al.  A Bichaperone (Hsp70-Hsp78) System Restores Mitochondrial DNA Synthesis following Thermal Inactivation of Mip1p Polymerase* , 2002, The Journal of Biological Chemistry.

[204]  T. Langer,et al.  EVIDENCE THAT THE NOVOBIOCIN‐SENSITIVE ATP‐BINDING SITE OF THE HEAT SHOCK PROTEIN 90 (HSP90) IS NECESSARY FOR ITS AUTOPHOSPHORYLATION , 2002, Cell biology international.

[205]  Xi Chen,et al.  ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. , 2002, Developmental cell.

[206]  S. Kaul,et al.  An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: what, when, and where? , 2002, Cell stress & chaperones.

[207]  V. Korolchuk,et al.  CK2 and GAK/auxilin2 Are Major Protein Kinases in Clathrin‐Coated Vesicles , 2002, Traffic.

[208]  Keiji Tanaka,et al.  Selective Proteasomal Dysfunction in the Hippocampal CA1 Region after Transient Forebrain Ischemia , 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[209]  F. Hartl,et al.  Ligand Discrimination by TPR Domains , 2002, The Journal of Biological Chemistry.

[210]  C. Sung,et al.  Characterization of a Brain-enriched Chaperone, MRJ, That Inhibits Huntingtin Aggregation and Toxicity Independently* , 2002, The Journal of Biological Chemistry.

[211]  D. Rubinsztein,et al.  Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin. , 2002, Human molecular genetics.

[212]  M. Sherman,et al.  Hsp72 and Stress Kinase c-jun N-Terminal Kinase Regulate the Bid-Dependent Pathway in Tumor Necrosis Factor-Induced Apoptosis , 2002, Molecular and Cellular Biology.

[213]  F. Sharp,et al.  Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemia , 2002, Journal of neurochemistry.

[214]  S. Gonin,et al.  Hsp 27 as a Negative Regulator of Cytochrome c Release , 2001 .

[215]  Shihua Li,et al.  Chaperone Suppression of Cellular Toxicity of Huntingtin Is Independent of Polyglutamine Aggregation* , 2001, The Journal of Biological Chemistry.

[216]  R. Burgoyne,et al.  Phosphorylation of Cysteine String Protein by Protein Kinase A , 2001, The Journal of Biological Chemistry.

[217]  W. Pratt,et al.  Evidence for a Mechanism of Repression of Heat Shock Factor 1 Transcriptional Activity by a Multichaperone Complex* , 2001, The Journal of Biological Chemistry.

[218]  F. Hartl,et al.  Chaperonin-mediated de novo generation of prion protein aggregates. , 2001, Journal of molecular biology.

[219]  M. Akbar,et al.  Heat shock protein 27 shows a distinctive widespread spatial and temporal pattern of induction in CNS glial and neuronal cells compared to heat shock protein 70 and caspase 3 following kainate administration. , 2001, Brain research. Molecular brain research.

[220]  R. Gilmore,et al.  Hsp90 Phosphorylation Is Linked to Its Chaperoning Function , 2001, The Journal of Biological Chemistry.

[221]  D. Hirsh,et al.  RME-8, a conserved J-domain protein, is required for endocytosis in Caenorhabditis elegans. , 2001, Molecular biology of the cell.

[222]  R. Hawkes,et al.  Constitutive expression of heat shock protein HSP25 in the central nervous system of the developing and adult mouse , 2001, The Journal of comparative neurology.

[223]  H. Lehrach,et al.  Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease. , 2001, Human molecular genetics.

[224]  T. Jorgensen,et al.  Phosphorylation and oligomerization states of native pig brain HSP90 studied by mass spectrometry. , 2001, European journal of biochemistry.

[225]  K. Watanabe,et al.  Induction of mitochondrial heat shock protein 60 and 10 mRNAs following transient focal cerebral ischemia in the rat. , 2001, Brain research. Molecular brain research.

[226]  Jeong-Sun Seo,et al.  Hsp72 functions as a natural inhibitory protein of c‐Jun N‐terminal kinase , 2001, The EMBO journal.

[227]  T. Langer,et al.  Mitochondrial Hsp78, a member of the Clp/Hsp100 family in Saccharomyces cerevisiae, cooperates with Hsp70 in protein refolding , 2001, FEBS letters.

[228]  H. Itoh,et al.  Simultaneous induction of mitochondrial heat shock protein mRNAs in rat forebrain ischemia. , 2000, Brain research. Molecular brain research.

[229]  M. Inagaki,et al.  Identification of Mrj, a DnaJ/Hsp40 Family Protein, as a Keratin 8/18 Filament Regulatory Protein* , 2000, The Journal of Biological Chemistry.

[230]  Jacques Landry,et al.  Inhibition of Daxx-Mediated Apoptosis by Heat Shock Protein 27 , 2000, Molecular and Cellular Biology.

[231]  B. Henderson,et al.  Chaperonins are cell-signalling proteins: the unfolding biology of molecular chaperones , 2000, Expert Reviews in Molecular Medicine.

[232]  J. R. Smith,et al.  Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75. , 2000, Biochemical and biophysical research communications.

[233]  S. Srinivasula,et al.  Negative regulation of cytochrome c‐mediated oligomerization of Apaf‐1 and activation of procaspase‐9 by heat shock protein 90 , 2000, The EMBO journal.

[234]  N. Nukina,et al.  Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity. , 2000, Human molecular genetics.

[235]  Emad S. Alnemri,et al.  Negative regulation of the Apaf-1 apoptosome by Hsp70 , 2000, Nature Cell Biology.

[236]  E. Floor,et al.  Association of l-Glutamic Acid Decarboxylase to the 70-kDa Heat Shock Protein as a Potential Anchoring Mechanism to Synaptic Vesicles* , 2000, The Journal of Biological Chemistry.

[237]  Jörg Urban,et al.  A regulatory link between ER-associated protein degradation and the unfolded-protein response. , 2000, Nature Cell Biology.

[238]  Anne Bertolotti,et al.  Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response , 2000, Nature Cell Biology.

[239]  K. Mori Tripartite Management of Unfolded Proteins in the Endoplasmic Reticulum , 2000, Cell.

[240]  E. Ungewickell,et al.  Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation. , 2000, European journal of cell biology.

[241]  Peter Walter,et al.  Functional and Genomic Analyses Reveal an Essential Coordination between the Unfolded Protein Response and ER-Associated Degradation , 2000, Cell.

[242]  R. Weichselbaum,et al.  Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3 , 2000, Oncogene.

[243]  M. Gaestel,et al.  Mouse Hsp25, a small heat shock protein , 2000 .

[244]  D. Bechtold,et al.  Heat shock proteins Hsp27 and Hsp32 localize to synaptic sites in the rat cerebellum following hyperthermia. , 2000, Brain research. Molecular brain research.

[245]  J. Höhfeld,et al.  The Ubiquitin-related BAG-1 Provides a Link between the Molecular Chaperones Hsc70/Hsp70 and the Proteasome* , 2000, The Journal of Biological Chemistry.

[246]  E. Eisenberg,et al.  Role of Cyclin G-associated Kinase in Uncoating Clathrin-coated Vesicles from Non-neuronal Cells* , 2000, The Journal of Biological Chemistry.

[247]  E. Repasky,et al.  Characterization of native interaction of hsp110 with hsp25 and hsc70 , 2000, FEBS letters.

[248]  Junying Yuan,et al.  Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β , 2000, Nature.

[249]  H. Kampinga,et al.  Heat Shock Protein (Hsp) 40 Mutants Inhibit Hsp70 in Mammalian Cells* , 1999, The Journal of Biological Chemistry.

[250]  E. Solary,et al.  HSP27 inhibits cytochrome c‐dependent activation of procaspase‐9 , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[251]  D. Thiele,et al.  The Yeast Hsp110 Family Member, Sse1, Is an Hsp90 Cochaperone* , 1999, The Journal of Biological Chemistry.

[252]  P. Connell,et al.  Identification of CHIP, a Novel Tetratricopeptide Repeat-Containing Protein That Interacts with Heat Shock Proteins and Negatively Regulates Chaperone Functions , 1999, Molecular and Cellular Biology.

[253]  R. Cuesta,et al.  Control of mRNA decay by heat shock-ubiquitin-proteasome pathway. , 1999, Science.

[254]  G. Lyons,et al.  Mrj encodes a DnaJ-related co-chaperone that is essential for murine placental development. , 1999, Development.

[255]  C. Callaway,et al.  Geldanamycin Provides Posttreatment Protection Against Glutamate‐Induced Oxidative Toxicity in a Mouse Hippocampal Cell Line , 1999, Journal of neurochemistry.

[256]  R. Burgoyne,et al.  The cysteine-string domain of the secretory vesicle cysteine-string protein is required for membrane targeting. , 1998, The Biochemical journal.

[257]  R. Turner,et al.  The Chaperone BiP/GRP78 Binds to Amyloid Precursor Protein and Decreases Aβ40 and Aβ42 Secretion* , 1998, The Journal of Biological Chemistry.

[258]  R. Sapolsky,et al.  Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy , 1998, Annals of neurology.

[259]  I. Brown,et al.  Constitutive expression of heat shock proteins Hsp90, Hsc70, Hsp70 and Hsp60 in neural and non-neural tissues of the rat during postnatal development. , 1998, Cell stress & chaperones.

[260]  R. Voellmy,et al.  Repression of Heat Shock Transcription Factor HSF1 Activation by HSP90 (HSP90 Complex) that Forms a Stress-Sensitive Complex with HSF1 , 1998, Cell.

[261]  P. Kochanek,et al.  72-kDa heat shock protein and mRNA expression after controlled cortical impact injury with hypoxemia in rats. , 1998, Journal of neurotrauma.

[262]  M. Cheetham,et al.  Structure, function and evolution of DnaJ: conservation and adaptation of chaperone function. , 1998, Cell stress & chaperones.

[263]  S. Lindquist,et al.  Chaperone-supervised conversion of prion protein to its protease-resistant form. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[264]  N. Eberhardt,et al.  Small heat shock proteins inhibit in vitro Aβ1–42 amyloidogenesis , 1997 .

[265]  M. Ryan,et al.  The genes encoding mammalian chaperonin 60 and chaperonin 10 are linked head-to-head and share a bidirectional promoter. , 1997, Gene.

[266]  D. Hopkins,et al.  Constitutive expression of the 27‐kDa heat shock protein (Hsp27) in sensory and motor neurons of the rat nervous system , 1997, The Journal of comparative neurology.

[267]  Ronald L. Davis,et al.  Leonardo, a Drosophila 14-3-3 Protein Involved in Learning, Regulates Presynaptic Function , 1997, Neuron.

[268]  H. Matsuzaki,et al.  Activation of protein kinase B (Akt/RAC‐protein kinase) by cellular stress and its association with heat shock protein Hsp27 , 1997, FEBS letters.

[269]  M. Galigniana,et al.  Protein Phosphatase 5 Is a Major Component of Glucocorticoid Receptor·hsp90 Complexes with Properties of an FK506-binding Immunophilin* , 1997, The Journal of Biological Chemistry.

[270]  S. R. Terlecky,et al.  An Intralysosomal hsp70 Is Required for a Selective Pathway of Lysosomal Protein Degradation , 1997, The Journal of cell biology.

[271]  B. Soltys,et al.  CELL SURFACE LOCALIZATION OF THE 60 kDa HEAT SHOCK CHAPERONIN PROTEIN (hsp60) IN MAMMALIAN CELLS , 1997, Cell biology international.

[272]  A. Silverstein,et al.  The Tetratricopeptide Repeat Domain of Protein Phosphatase 5 Mediates Binding to Glucocorticoid Receptor Heterocomplexes and Acts as a Dominant Negative Mutant* , 1996, The Journal of Biological Chemistry.

[273]  D. Latchman,et al.  Focal cerebral ischaemia increases the levels of several classes of heat shock proteins and their corresponding mRNAs. , 1996, Brain research. Molecular brain research.

[274]  I. Brown,et al.  The neuronal stress response: nuclear translocation of heat shock proteins as an indicator of hyperthermic stress. , 1996, Experimental cell research.

[275]  E. Ungewickell,et al.  Mechanism of clathrin basket dissociation: separate functions of protein domains of the DnaJ homologue auxilin , 1996, The Journal of cell biology.

[276]  D. Wolf,et al.  ER Degradation of a Misfolded Luminal Protein by the Cytosolic Ubiquitin-Proteasome Pathway , 1996, Science.

[277]  R. Simon,et al.  Stress Proteins and Tolerance to Focal Cerebral Ischemia , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[278]  M. Famulok,et al.  Prion protein PrPc interacts with molecular chaperones of the Hsp60 family , 1996, Journal of virology.

[279]  B. Soltys,et al.  Immunoelectron microscopic localization of the 60-kDa heat shock chaperonin protein (Hsp60) in mammalian cells. , 1996, Experimental cell research.

[280]  E. Eisenberg,et al.  Role of auxilin in uncoating clathrin-coated vesicles , 1995, Nature.

[281]  J. Weissman,et al.  Mechanism of GroEL action: Productive release of polypeptide from a sequestered position under groes , 1995, Cell.

[282]  W. D. de Jong,et al.  Reduced Chaperone-like Activity of αAins-crystallin, an Alternative Splicing Product Containing a Large Insert Peptide (*) , 1995, The Journal of Biological Chemistry.

[283]  H. Schröder,et al.  Constitutive expression of heat shock protein 90 (HSP90) in neurons of the rat brain , 1994, Neuroscience Letters.

[284]  M. Bauer,et al.  Mitochondrial Hsp70/MIM44 complex facilitates protein import , 1994, Nature.

[285]  C. Gundersen,et al.  Extensive lipidation of a Torpedo cysteine string protein. , 1994, The Journal of biological chemistry.

[286]  Y. Tan,et al.  Dephosphorylation of the small heat shock protein Hsp27 in vivo by protein phosphatase 2A. , 1994, The Journal of biological chemistry.

[287]  Yong Liu,et al.  Induction of 27-kDa heat shock protein following cerebral ischemia in a rat model of ischemic tolerance , 1994, Brain Research.

[288]  F. Sharp,et al.  Induction of heat shock hsp70 mRNA and HSP70 kDa protein in neurons in the ‘penumbra’ following focal cerebral ischemia in the rat , 1993, Brain Research.

[289]  M. Gaestel,et al.  Structure and organisation of a murine gene encoding small heat-shock protein Hsp25. , 1993, Gene.

[290]  J. Herbert,et al.  Widespread constitutive expression of HSP90 messenger RNA in rat brain , 1993, Journal of neuroscience research.

[291]  Michael Chopp,et al.  Distribution of the 72‐kd Heat‐Shock Protein as a Function of Transient Focal Cerebral Ischemia in Rats , 1992, Stroke.

[292]  G. Schatz,et al.  Sequential action of mitochondrial chaperones in protein import into the matrix. , 1991, The EMBO journal.

[293]  J. Said,et al.  Pathology of malignant lymphomas , 1990, Current opinion in oncology.

[294]  C. Anderson,et al.  The human double-stranded DNA-activated protein kinase phosphorylates the 90-kDa heat-shock protein, hsp90 alpha at two NH2-terminal threonine residues. , 1989, The Journal of biological chemistry.

[295]  G. Kramer,et al.  The phosphorylation state of the reticulocyte 90-kDa heat shock protein affects its ability to increase phosphorylation of peptide initiation factor 2 alpha subunit by the heme-sensitive kinase. , 1989, Biochemistry.

[296]  A. Myers,et al.  Characterization of the yeast HSP60 gene coding for a mitochondrial assembly factor , 1989, Nature.

[297]  C. Anderson,et al.  Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II. , 1989, The Journal of biological chemistry.

[298]  J. Rothman,et al.  Uncoating ATPase is a member of the 70 kilodalton family of stress proteins , 1986, Cell.

[299]  D. Schlegel [Occupational diseases of dentists]. , 1976, Der Freie Zahnarzt.

[300]  J. Ávila,et al.  Binding of Hsp90 to tau promotes a conformational change and aggregation of tau protein. , 2009, Journal of Alzheimer's disease : JAD.

[301]  S. Charette,et al.  Identification of the key structural motifs involved in HspB8/HspB6-Bag3 interaction. , 2009, The Biochemical journal.

[302]  S. Wickner,et al.  Hsp104 and ClpB: protein disaggregating machines. , 2009, Trends in biochemical sciences.

[303]  Bin Chen,et al.  Guidelines for the nomenclature of the human heat shock proteins , 2008, Cell Stress and Chaperones.

[304]  A. Braun,et al.  RDJ2 (DNAJA2) chaperones neural G protein signaling pathways , 2008, Cell Stress and Chaperones.

[305]  C. Faulkner,et al.  The GRV2/RME-8 protein of Arabidopsis functions in the late endocytic pathway and is required for vacuolar membrane flow. , 2008, The Plant journal : for cell and molecular biology.

[306]  A. Bryantsev,et al.  Recruitment of phosphorylated small heat shock protein Hsp27 to nuclear speckles without stress. , 2007, Experimental cell research.

[307]  Sheng Chen,et al.  Neuronal expression of constitutive heat shock proteins: implications for neurodegenerative diseases , 2007, Cell stress & chaperones.

[308]  David M. Taylor,et al.  Characterizing the role of Hsp90 in production of heat shock proteins in motor neurons reveals a suppressive effect of wild-type Hsf1 , 2007, Cell stress & chaperones.

[309]  E. Craig,et al.  The diverse roles of J-proteins, the obligate Hsp70 co-chaperone. , 2006, Reviews of physiology, biochemistry and pharmacology.

[310]  M. Cheetham,et al.  Downstream caspases are novel targets for the antiapoptotic activity of the molecular chaperone Hsp70 , 2004, Cell stress & chaperones.

[311]  S. Alberti,et al.  BAG-1—a nucleotide exchange factor of Hsc70 with multiple cellular functions , 2003, Cell stress & chaperones.

[312]  A. Nanda,et al.  Heat shock proteins expression in brain stem after subarachnoid hemorrhage in rats. , 2003, Acta neurochirurgica. Supplement.

[313]  M. Hori,et al.  Synergistic induction of HSP40 and HSC70 in the mouse hippocampal neurons after cerebral ischemia and ischemic tolerance in gerbil hippocampus , 2002, Journal of neuroscience research.

[314]  Anders D. Børglum,et al.  Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter , 2002, Human Genetics.

[315]  S. Orrenius,et al.  Hsp27 inhibits cytochrome c-mediated caspase activation by sequestering both pro-caspase-3 and cytochrome c. , 2001, Gene expression.

[316]  S. Orrenius,et al.  Hsp27 protects mitochondria of thermotolerant cells against apoptotic stimuli , 2001, Cell stress & chaperones.

[317]  P. Connell,et al.  The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins , 2000, Nature Cell Biology.

[318]  A. Horwich,et al.  Structure and function in GroEL-mediated protein folding. , 1998, Annual review of biochemistry.

[319]  Itoh Hideaki,et al.  Localization of HSP90 in rat brain , 1993 .

[320]  T. Wisniewski,et al.  Accumulation of alpha B-crystallin in central nervous system glia and neurons in pathologic conditions. , 1992, The American journal of pathology.