Common-path digital holographic microscopy and its applications

To significantly increase the stability of the digital holographic microscope, some common-path configurations with a piece of glass plate, Lloyd mirror and lensless structure are introduced in digital holographic microscopy to make up several compact experiment systems. Meanwhile, dual-wavelength technique and some numerical algorithms are also employed to improve the measurement accuracy. As examples, we apply these configurations to measure a mouse osteoblastic cell, laser ablated pit specimen and silicon wafer. The experiment results show the feasibility of the proposed configurations.

[1]  Myung K. Kim,et al.  Measurement of the traction force of biological cells by digital holography , 2011, Biomedical optics express.

[2]  Mikiya Muramatsu,et al.  Photorefractive digital holographic microscopy applied in microstructures analysis , 2013 .

[3]  Björn Kemper,et al.  Simplified approach for quantitative digital holographic phase contrast imaging of living cells. , 2011, Journal of biomedical optics.

[4]  Jianlin Zhao,et al.  Digital holographic interferometry based on wavelength and angular multiplexing for measuring the ternary diffusion. , 2012, Optics letters.

[5]  Zeev Zalevsky,et al.  Spatially-multiplexed interferometric microscopy (SMIM): converting a standard microscope into a holographic one. , 2014, Optics express.

[6]  Johannes Schwider,et al.  Three channel phase-shifting interferometer using polarization-optics and a diffraction grating , 2000 .

[7]  A. Asundi,et al.  Digital holographic microscopy with physical phase compensation. , 2009, Optics letters.

[8]  Bahram Javidi,et al.  Self-referencing digital holographic microscope for dynamic imaging of living cells , 2014, Sensing Technologies + Applications.

[9]  Jong Chul Ye,et al.  Self-reference quantitative phase microscopy for microfluidic devices. , 2010, Optics letters.

[10]  Bahram Javidi,et al.  Highly stable digital holographic microscope using Sagnac interferometer. , 2015, Optics letters.

[11]  Pinhas Girshovitz,et al.  Optical‐mechanical signatures of cancer cells based on fluctuation profiles measured by interferometry , 2014, Journal of biophotonics.

[12]  Baoli Yao,et al.  Parallel two-step phase-shifting point-diffraction interferometry for microscopy based on a pair of cube beamsplitters. , 2011, Optics express.

[13]  Baoli Yao,et al.  Single-shot parallel four-step phase shifting using on-axis Fizeau interferometry. , 2012, Applied optics.

[14]  Steven L Jacques,et al.  Design and calibration of a digital Fourier holographic microscope for particle sizing via goniometry and optical scatter imaging in transmission. , 2016, Optics express.

[15]  Mingguang Shan,et al.  Common path interferometer based on the modified Michelson configuration using a reflective grating , 2015 .

[16]  Melania Paturzo,et al.  Common-path configuration in total internal reflection digital holography microscopy , 2014, Photonics Europe.

[17]  I. Yamaguchi,et al.  Three-dimensional microscopy with phase-shifting digital holography. , 1998, Optics letters.

[18]  Bahram Javidi,et al.  Quantitative phase-contrast imaging with compact digital holographic microscope employing Lloyd's mirror. , 2012, Optics letters.

[19]  R. Dasari,et al.  Diffraction phase microscopy for quantifying cell structure and dynamics. , 2006, Optics letters.

[20]  Jianlin Zhao,et al.  Transmission and total internal reflection integrated digital holographic microscopy. , 2016, Optics letters.

[21]  Anand Asundi,et al.  Compact Lens-less Digital Holographic Microscope for MEMS Inspection and Characterization. , 2016, Journal of visualized experiments : JoVE.

[22]  Natan T Shaked,et al.  Quantitative phase microscopy of biological samples using a portable interferometer. , 2012, Optics letters.

[23]  Jianlin Zhao,et al.  Dynamical measurement of refractive index distribution using digital holographic interferometry based on total internal reflection. , 2015, Optics express.

[24]  Zhou Jianbo,et al.  Visualizations of Light-induced Refractive Index Changes in Photorefractive Crystals Employing Digital Holography , 2003 .

[25]  Xiaoxu Lu,et al.  Simultaneous multi-wavelength phase-shifting interferometry based on principal component analysis with a color CMOS , 2016 .

[26]  Myung K. Kim.  Principles and techniques of digital holographic microscopy , 2010 .

[27]  Jianlin Zhao,et al.  Real-time monitoring of the solution concentration variation during the crystallization process of protein-lysozyme by using digital holographic interferometry. , 2012, Optics express.

[28]  Jing-Wei Su,et al.  Tomographic diffractive microscopy of living cells based on a common-path configuration. , 2014, Optics letters.