Single-chip pulse programmer for magnetic resonance imaging using a 32-bit microcontroller.

A magnetic resonance imaging (MRI) pulse programmer has been developed using a single-chip microcontroller (ADmicroC7026). The microcontroller includes all the components required for the MRI pulse programmer: a 32-bit RISC CPU core, 62 kbytes of flash memory, 8 kbytes of SRAM, two 32-bit timers, four 12-bit DA converters, and 40 bits of general purpose I/O. An evaluation board for the microcontroller was connected to a host personal computer (PC), an MRI transceiver, and a gradient driver using interface circuitry. Target (embedded) and host PC programs were developed to enable MRI pulse sequence generation by the microcontroller. The pulse programmer achieved a (nominal) time resolution of approximately 100 ns and a minimum time delay between successive events of approximately 9 micros. Imaging experiments using the pulse programmer demonstrated the effectiveness of our approach.

[1]  E. A. Wachter,et al.  Enhanced state‐machine pulse programmer for very‐high‐precision pulse programming , 1988 .

[2]  Tomoyuki Haishi,et al.  Development of a Flexible Pulse Programmer for MRI Using a Commercial Digital Signal Processor Board , 2007 .

[3]  Siegfried Stapf,et al.  NMR Imaging in Chemical Engineering , 2006 .

[4]  Roberto S. Sarthour,et al.  DESIGN NOTE: A field-programmable gate-array-based high-resolution pulse programmer , 2003 .

[5]  Tomoyuki Haishi,et al.  Development of a compact mouse MRI using a yokeless permanent magnet. , 2005, Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine.

[6]  Kazuyuki Takeda,et al.  A highly integrated FPGA-based nuclear magnetic resonance spectrometer. , 2007, The Review of scientific instruments.

[7]  T Haishi,et al.  Development of a 1.0 T MR microscope using a Nd-Fe-B permanent magnet. , 2001, Magnetic resonance imaging.

[8]  Katsumi Kose,et al.  Development of a compact MRI system for measuring the trabecular bone microstructure of the finger , 2007, Magnetic resonance in medicine.

[9]  A. Haase,et al.  Portable nuclear magnetic resonance imaging system , 2000 .

[10]  Liu Ying,et al.  Home-built magnetic resonance imaging system (0.3 T) with a complete digital spectrometer , 2005 .

[11]  E. Fukushima,et al.  Spatially Resolved Magnetic Resonance , 1998 .

[12]  Tomoyuki Haishi,et al.  Development of a compact MRI system for trabecular bone volume fraction measurements , 2004, Magnetic resonance in medicine.

[13]  Hisashi Yoshida,et al.  Personal computer-controlled 16 channel versatile pulse generator for nuclear magnetic resonance , 1997 .