PI3K/AKT inhibitor BEZ-235 targets CCND2 and induces G1 arrest in breast implant-associated anaplastic large cell lymphoma.
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S. Bens | C. Uphoff | H. Quentmeier | M. Zaborski | C. Pommerenke | S. Nagel | V. Hauer | R. Siebert | Anja Fischer
[1] H. Quentmeier,et al. Genomic Aberrations Generate Fusion Gene FOXK2::TP63 and Activate NFKB1 in Cutaneous T-Cell Lymphoma , 2022, Biomedicines.
[2] A. Rosenwald,et al. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms , 2022, Leukemia.
[3] C. Pommerenke,et al. DSMZCellDive: Diving into high-throughput cell line data , 2022, F1000Research.
[4] R. Geffers,et al. Inhibition of MCL1 induces apoptosis in anaplastic large cell lymphoma and in primary effusion lymphoma , 2022, Scientific Reports.
[5] A. Deva,et al. What are the likely causes of breast implant associated anaplastic large cell lymphoma (BIA-ALCL)? , 2022, JPRAS open.
[6] Marilyn M. Li,et al. Rational drug combinations with CDK4/6 inhibitors in acute lymphoblastic leukemia , 2021, Haematologica.
[7] C. Uphoff,et al. Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies , 2021, PloS one.
[8] M. Copland,et al. The application of BH3 mimetics in myeloid leukemias , 2021, Cell Death and Disease.
[9] R. Thijssen,et al. BH3 Mimetics for the Treatment of B-Cell Malignancies—Insights and Lessons from the Clinic , 2020, Cancers.
[10] Verena Wagner,et al. Senescence as a therapeutically relevant response to CDK4/6 inhibitors , 2020, Oncogene.
[11] G. Inghirami,et al. Cell of Origin and Immunologic Events in the Pathogenesis of Breast Implant–Associated Anaplastic Large-Cell Lymphoma , 2020, The American journal of pathology.
[12] Yu Cao,et al. CDK7 inhibitor THZ1 inhibits MCL1 synthesis and drives cholangiocarcinoma apoptosis in combination with BCL2/BCL-XL inhibitor ABT-263 , 2019, Cell Death & Disease.
[13] H. Drexler,et al. The LL-100 panel: 100 cell lines for blood cancer studies , 2019, Scientific Reports.
[14] M. Kadin. What Cytokines Can Tell Us About the Pathogenesis of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL). , 2019, Aesthetic surgery journal.
[15] A. Valencia,et al. DNA methylation profiling of hepatosplenic T-cell lymphoma , 2018, Haematologica.
[16] L. Medeiros,et al. Breast implant-associated anaplastic large cell lymphoma: a review , 2018, Modern Pathology.
[17] T. Waldmann,et al. Cytokine receptor signaling is required for the survival of ALK− anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations , 2017, Proceedings of the National Academy of Sciences.
[18] Daniel J. Weisenberger,et al. Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling , 2016, Cell reports.
[19] Jie Jin,et al. The Silencing of CCND2 by Promoter Aberrant Methylation in Renal Cell Cancer and Analysis of the Correlation between CCND2 Methylation Status and Clinical Features , 2016, PloS one.
[20] R. Roskoski. Cyclin-dependent protein kinase inhibitors including palbociclib as anticancer drugs. , 2016, Pharmacological research.
[21] G. von Heijne,et al. Tissue-based map of the human proteome , 2015, Science.
[22] M. Toribio,et al. Regulation of the transcriptional program by DNA methylation during human αβ T-cell development , 2014, Nucleic acids research.
[23] Martin J. Aryee,et al. Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays , 2014, Bioinform..
[24] Xiaomei Ma,et al. A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network , 2012, Nucleic acids research.
[25] A. Epstein,et al. Survival Signals and Targets for Therapy in Breast Implant–Associated ALK− Anaplastic Large Cell Lymphoma , 2012, Clinical Cancer Research.
[26] B. Falini,et al. Anaplastic large cell lymphoma: changes in the World Health Organization classification and perspectives for targeted therapy , 2009, Haematologica.
[27] H. Drexler,et al. SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines , 2009, Journal of hematology & oncology.
[28] C. Proud,et al. Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1 , 2008, Oncogene.
[29] S. Kotani,et al. Glycogen synthase kinase-3β and p38 phosphorylate cyclin D2 on Thr280 to trigger its ubiquitin/proteasome-dependent degradation in hematopoietic cells , 2007, Oncogene.
[30] R. Siebert,et al. FISH analysis for the detection of lymphoma-associated chromosomal abnormalities in routine paraffin-embedded tissue. , 2006, The Journal of molecular diagnostics : JMD.
[31] L. Staudt,et al. Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling. , 2005, Blood.
[32] R. Siebert,et al. Molecular cytogenetic detection of chromosomal breakpoints in T-cell receptor gene loci , 2003, Leukemia.
[33] D. Johnson,et al. Cyclins and cell cycle checkpoints. , 1999, Annual review of pharmacology and toxicology.
[34] M. Höglund,et al. Genomic amplification of CCND2 is rare in non-Hodgkin lymphomas. , 1998, Cancer genetics and cytogenetics.
[35] Sibylle Mittnacht,et al. Differential Phosphorylation of the Retinoblastoma Protein by G1/S Cyclin-dependent Kinases* , 1997, The Journal of Biological Chemistry.
[36] S. Moreno,et al. Regulation of CDK/cyclin complexes during the cell cycle. , 1997, The international journal of biochemistry & cell biology.
[37] E. Harlow,et al. Identification of G1 kinase activity for cdk6, a novel cyclin D partner , 1994, Molecular and cellular biology.
[38] Tai Wang,et al. Migratory localization of cyclin D2-Cdk4 complex suggests a spatial regulation of the G1-S transition. , 2008, Cell structure and function.
[39] F. Sigaux,et al. Cyclin D2 dysregulation by chromosomal translocations to TCR loci in T-cell acute lymphoblastic leukemias , 2006, Leukemia.