N-(p-Tolylsulfonyl)-l-asparagine

In the title compound, C11H14N2O5S, the amide O atom acts as a hydrogen-bond acceptor from a carboxylate O atom and a secondary amino N atom. In addition, one of the sulfonyl O atoms and the carbonyl O atom of the carboxyl group also form hydrogen bonds with the primary amido N atom. These intermolecular hydrogen-bonding interactions give rise to a layer structure, with the layers parallel to the ac plane.

[1]  J. Stubbins,et al.  Synthesis and anticancer activity of asparagine analogs. , 1980, Journal of pharmaceutical sciences.

[2]  Muhammad Nadeem Arshad,et al.  (2R)-2-Benzenesulfonamido-2-phenylethanoic acid , 2009, Acta crystallographica. Section E, Structure reports online.

[3]  T. Miyagishima,et al.  Synthesis and antibacterial activity of asparagine derivatives of aminobenzylpenicillin. , 1983, The Journal of antibiotics.

[4]  H. Flack,et al.  On enantiomorph‐polarity estimation , 1983 .

[5]  G. Sheldrick.  A short history of SHELX. , 2008, Acta crystallographica. Section A, Foundations of crystallography.

[6]  Leonard J. Barbour,et al.  X-Seed — A Software Tool for Supramolecular Crystallography , 2001 .

[7]  G. G. Stokes.  "J." , 1890, The New Yale Book of Quotations.