Somatic mutations of the histone H3K27 demethylase, UTX, in human cancer

Bin Tean Teh | Chai Yin Kok | Andrew Menzies | Sarah Edkins | Sara Widaa | Rebecca Shepherd | Simon Forbes | Paul Wray | David Jones | Helen Davies | Patrick S Tarpey | Peter J Campbell | Michael R Stratton | Erin Pleasance | V. P. Collins | Syd Barthorpe | Mark Maddison | Adam Butler | Sok Kean Khoo | Gurpreet W. Tang | Lucy Stebbings | Catherine Leroy | Sarah O’Meara | Jonathan Hinton | Jennifer Cole | Suet Yi Leung | Claire Hardy | Koichi Ichimura | Simon Law | M. Stratton | K. McLay | P. Futreal | P. Campbell | P. Stephens | E. Pleasance | S. O'meara | L. Stebbings | Catherine Leroy | S. Edkins | C. Hardy | J. Teague | A. Menzies | G. Bignell | G. Tonon | R. DePinho | P. Tarpey | C. Greenman | D. Beare | A. Butler | Jonathan Hinton | M. Jia | David Jones | C. Latimer | D. McBride | L. Mudie | Meng-Lay Lin | H. Davies | G. Dalgliesh | R. Kahnoski | B. Teh | Lina Chen | J. Andrews | S. Barthorpe | G. Buck | S. Forbes | C. Kok | M. Maddison | T. Mironenko | R. Shepherd | Raffaella Smith | G. Tang | K. Turrell | S. Khoo | S. Leung | S. Yuen | S. Law | J. Wong | S. West | K. Ichimura | S. Widaa | J. Cole | J. Varian | Y. Tai | R. Dunmore | Rachel Turner | P. Wray | G. van Haaften | Yu-Tzu Tai | Jon Teague | Gemma Buck | Tatiana Mironenko | Jennifer Varian | Sofie West | P Andrew Futreal | Raffaella Smith | Philip Stephens | Chris Greenman | Graham Bignell | V Peter Collins | Kenneth C Anderson | Meng-Lay Lin | Gillian L Dalgliesh | Gijs van Haaften | Ronald A DePinho | Laura Mudie | Giovanni Tonon | Calli Latimer | Mingming Jia | John Wong | Siu Tsan Yuen | Lina Chen | Jenny Andrews | Dave Beare | Rebecca Dunmore | David J McBride | Simon Maquire | Kirsten McLay | Mulderrig Lee | Gurpreet Tang | Rachel Turner | Kelly Turrell | Richard J. Kahnoski | Aaron Massie | K. Anderson | Calli Latimer | S. Maquire | Mulderrig Lee | A. Massie | V. Collins | Rebecca Shepherd | Mingming Jia | Meng‐Lay Lin | Claire W. Hardy | D. Mcbride | S. O’Meara

[1]  Pan Du,et al.  lumi: a pipeline for processing Illumina microarray , 2008, Bioinform..

[2]  J. Licht,et al.  The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. , 2008, Blood.

[3]  W. Huber,et al.  Model-based variance-stabilizing transformation for Illumina microarray data , 2008, Nucleic acids research.

[4]  Ji-Young Kim,et al.  Multiple Myeloma-Related WHSC1/MMSET Isoform RE-IIBP Is a Histone Methyltransferase with Transcriptional Repression Activity , 2008, Molecular and Cellular Biology.

[5]  T. Veenstra,et al.  Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases , 2007, Proceedings of the National Academy of Sciences.

[6]  Min Gyu Lee,et al.  Demethylation of H3K27 Regulates Polycomb Recruitment and H2A Ubiquitination , 2007, Science.

[7]  I. Issaeva,et al.  UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development , 2007, Nature.

[8]  Howard Y. Chang,et al.  A histone H3 lysine 27 demethylase regulates animal posterior development , 2007, Nature.

[9]  G. Pan,et al.  Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. , 2007, Cell stem cell.

[10]  E. Birney,et al.  Patterns of somatic mutation in human cancer genomes , 2007, Nature.

[11]  T. Kouzarides.  Chromatin Modifications and Their Function , 2007, Cell.

[12]  A. Feinberg,et al.  An X Chromosome Gene, WTX, Is Commonly Inactivated in Wilms Tumor , 2007, Science.

[13]  Zohar Yakhini,et al.  Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer , 2007, Nature Genetics.

[14]  Leonard I Zon,et al.  Cell stem cell. , 2007, Cell stem cell.

[15]  C. Croce,et al.  Knockdown of ALR (MLL2) Reveals ALR Target Genes and Leads to Alterations in Cell Adhesion and Growth , 2006, Molecular and Cellular Biology.

[16]  Kristian Helin,et al.  Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. , 2006, Genes & development.

[17]  Gordon K Smyth,et al.  Statistical Applications in Genetics and Molecular Biology Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments , 2011 .

[18]  V. Diehl,et al.  Correlation of chromosomal aberrations in a myeloma cell line with tumorigenicity in nude mice , 1981, Blut.

[19]  A. Monaco,et al.  The UTX gene escapes X inactivation in mice and humans. , 1998, Human molecular genetics.

[20]  P. Sperryn,et al.  Blood. , 1989, British journal of sports medicine.

[21]  M. Boccadoro,et al.  The human myeloma cell line LP-1: a versatile model in which to study early plasma-cell differentiation and c-myc activation. , 1989, Blood.