An efficient metal-free cascade process for the synthesis of 4-arylpyrimido[1,2-b]indazole-3-carbonitrile derivatives

[1]  S. Balwe,et al.  A novel three-component method for the synthesis of spiro[chromeno [4′,3′:4,5] pyrimido[1,2-b] indazole-7,3′-indoline]-2′,6(9H)-dione , 2017 .

[2]  S. Schaus,et al.  Multicomponent Condensation Reactions via ortho-Quinone Methides. , 2017, Organic letters.

[3]  Huanfeng Jiang,et al.  Synthesis of Polysubstituted 3-Amino Pyrroles via Palladium-Catalyzed Multicomponent Reaction. , 2017, The Journal of organic chemistry.

[4]  X. García‐Mera,et al.  Multicomponent Assembly of the Kinesin Spindle Protein Inhibitor CPUYJ039 and Analogues as Antimitotic Agents. , 2017, ACS combinatorial science.

[5]  Yanlong Gu,et al.  Aldo-X Bifunctional Building Blocks for the Synthesis of Heterocycles. , 2017, Chemical record.

[6]  Om P. S. Patel,et al.  Antileishmanial Activity of Pyrazolopyridine Derivatives and Their Potential as an Adjunct Therapy with Miltefosine. , 2017, Journal of medicinal chemistry.

[7]  M. Valan Arasu,et al.  A Metal-Free Regioselective Multicomponent Approach for the Synthesis of Free Radical Scavenging Pyrimido-Fused Indazoles and Their Fluorescence Studies , 2016, Molecules.

[8]  V. V. Shinde,et al.  Sonochemical FeF3 catalyzed three-component synthesis of densely functionalized tetrahydroindazolo[3,2-b]quinazoline under solvent-free conditions , 2016 .

[9]  V. V. Shinde,et al.  Organic-base-catalyzed diversity-oriented synthesis of novel pyrimido[1,2-b]indazole-3-carbonitrile , 2016 .

[10]  L. Zhou,et al.  Multicomponent Reactions of Aldo‐X Bifunctional Reagent α‐Oxoketene Dithioacetals and Indoles or Amines: Divergent Synthesis of Dihydrocoumarins, Quinolines, Furans, and Pyrroles , 2016 .

[11]  S. Roopan,et al.  One-pot synthesis of highly functionalized pyrimido[1,2-b]indazoles via 6-endo-dig cyclization , 2016 .

[12]  S. Roopan,et al.  Iodine-mediated synthesis of indazolo-quinazolinones via a multi-component reaction , 2015 .

[13]  A. Taheri,et al.  Condition-determined multicomponent reactions of 1,3-dicarbonyl compounds and formaldehyde. , 2014, ACS combinatorial science.

[14]  Vishal Rai,et al.  Small heterocycles in multicomponent reactions. , 2014, Chemical reviews.

[15]  Eelco Ruijter,et al.  Multicomponent reactions: advanced tools for sustainable organic synthesis , 2014 .

[16]  S. Adil,et al.  Synthesis of pyrazolo[1,5-a]pyrimidine linked aminobenzothiazole conjugates as potential anticancer agents. , 2013, Bioorganic & medicinal chemistry letters.

[17]  M. Tahir,et al.  Synthesis, antibacterial activity and cytotoxicity of new fused pyrazolo[1,5-a]pyrimidine and pyrazolo[5,1-c][1,2,4]triazine derivatives from new 5-aminopyrazoles. , 2013, European journal of medicinal chemistry.

[18]  A. Maleki,et al.  Potassium phthalimide-N-oxyl: a novel, efficient, and simple organocatalyst for the one-pot three-component synthesis of various 2-amino-4H-chromene derivatives in water , 2013 .

[19]  Annelaure Damont,et al.  Pyrazolo[1,5-a]pyrimidine acetamides: 4-Phenyl alkyl ether derivatives as potent ligands for the 18 kDa translocator protein (TSPO). , 2010, Bioorganic & medicinal chemistry letters.

[20]  O. Ahmed,et al.  Synthesis and anti-tumor activities of some new pyridines and pyrazolo[1,5-a]pyrimidines. , 2009, European journal of medicinal chemistry.

[21]  Denis Guilloteau,et al.  DPA-714, a New Translocator Protein–Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization , 2008, Journal of Nuclear Medicine.

[22]  S. Ji,et al.  Facile and efficient synthesis of a new class of bis(3?indolyl)pyridine derivatives via one-pot multicomponent reactions , 2008 .

[23]  C. Martini,et al.  A novel selective GABA(A) alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents. , 2005, Journal of medicinal chemistry.

[24]  B. Jiang,et al.  Synthesis of novel analogues of marine indole alkaloids: mono(indolyl)-4-trifluoromethylpyridines and bis(indolyl)-4-trifluoromethylpyridines as potential anticancer agents. , 2001, Bioorganic & medicinal chemistry.

[25]  K. Weitzel,et al.  Zaleplon: a pyrazolopyrimidine sedative-hypnotic agent for the treatment of insomnia. , 2000, Clinical therapeutics.

[26]  G. Gribble.  Recent developments in indole ring synthesis—methodology and applications , 2010 .

[27]  P. Molina,et al.  Intramolecular trapping of a phosphazide by an imine: formation of 2,3-diamino-2H-indazole derivatives from o-azidobenzaldimines and tertiary phosphines , 1989 .