Production of recombinant proteins by filamentous fungi.
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[1] A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases , 2011, The Journal of Antibiotics.
[2] Ping Wang,et al. Molecular cloning and expression analysis of a delta 6-fatty acid desaturase gene from Rhizopus stolonifer strain YF6 which can accumulate high levels of gamma-linolenic acid , 2011, The Journal of Microbiology.
[3] Angray S. Kang,et al. Development of Transgenic Fungi That Kill Human Malaria Parasites in Mosquitoes , 2011, Science.
[4] Gerhard Adam,et al. FGDB: revisiting the genome annotation of the plant pathogen Fusarium graminearum , 2010, Nucleic Acids Res..
[5] L. D. de Graaff,et al. Proteomics of industrial fungi: trends and insights for biotechnology , 2010, Applied microbiology and biotechnology.
[6] J. Wynn. Lipids, Fatty Acids , 2011 .
[7] N. Kelleher,et al. Surveys of non-ribosomal peptide and polyketide assembly lines in fungi and prospects for their analysis in vitro and in vivo. , 2011, Fungal genetics and biology : FG & B.
[8] C. Shin,et al. Expression of recombinant human interleukin-32 in Pleurotus eryngii , 2011, Annals of Microbiology.
[9] K. Kitamoto,et al. Disruption of ten protease genes in the filamentous fungus Aspergillus oryzae highly improves production of heterologous proteins , 2011, Applied Microbiology and Biotechnology.
[10] E. Martens-Uzunova,et al. An inventory of the Aspergillus niger secretome by combining in silico predictions with shotgun proteomics data , 2010, BMC Genomics.
[11] J. A. Teixeira,et al. Pectin lyase production by recombinant Penicillium griseoroseum strain 105. , 2010, Canadian journal of microbiology.
[12] Zhi‐hua Liu,et al. Cloning and Heterologous Expression of a Novel Endoglucanase Gene egVIII from Trichoderma viride in Saccharomyces cerevisiae , 2010, Applied biochemistry and biotechnology.
[13] Eiji Munetsuna,et al. Enzyme systems for biodegradation of polychlorinated dibenzo-p-dioxins , 2010, Applied Microbiology and Biotechnology.
[14] Ya. E. Sergeeva,et al. Biodiesel-fuel: Content, production, producers, contemporary biotechnology (Review) , 2010, Applied Biochemistry and Microbiology.
[15] S. Sze,et al. Quantitative iTRAQ secretome analysis of Aspergillus niger reveals novel hydrolytic enzymes. , 2010, Journal of proteome research.
[16] K. Kitamoto,et al. Enhanced Production and Secretion of Heterologous Proteins by the Filamentous Fungus Aspergillus oryzae via Disruption of Vacuolar Protein Sorting Receptor Gene Aovps10 , 2010, Applied and Environmental Microbiology.
[17] N. Callewaert,et al. Engineering of glycosylation in yeast and other fungi: current state and perspectives , 2010, Applied Microbiology and Biotechnology.
[18] M. Schmoll,et al. Recombinant production of an Aspergillus nidulans class I hydrophobin (DewA) in Hypocrea jecorina (Trichoderma reesei) is promoter-dependent , 2010, Applied Microbiology and Biotechnology.
[19] A. Fleissner,et al. Expression and export: recombinant protein production systems for Aspergillus , 2010, Applied Microbiology and Biotechnology.
[20] S. Ying,et al. Integration of Insecticidal Protein Vip3Aa1 into Beauveria bassiana Enhances Fungal Virulence to Spodoptera litura Larvae by Cuticle and PerOs Infection , 2010, Applied and Environmental Microbiology.
[21] Monika Schmoll,et al. Biology and biotechnology of Trichoderma , 2010, Applied Microbiology and Biotechnology.
[22] A. Chulkin,et al. A heterologous production of the Trametes hirsuta laccase in the fungus Penicillium canescens , 2010, Applied Biochemistry and Microbiology.
[23] N. Aoki,et al. Changes in nitrogen assimilation, metabolism, and growth in transgenic rice plants expressing a fungal NADP(H)-dependent glutamate dehydrogenase (gdhA) , 2010, Planta.
[24] Christoph Wittmann,et al. Morphology engineering of Aspergillus niger for improved enzyme production , 2010, Biotechnology and bioengineering.
[25] J. Napier,et al. An alternative to fish oils: Metabolic engineering of oil-seed crops to produce omega-3 long chain polyunsaturated fatty acids. , 2010, Progress in lipid research.
[26] K. Tang,et al. A review: recent advances and future prospects of taxol-producing endophytic fungi , 2010, Applied Microbiology and Biotechnology.
[27] K. Akimitsu,et al. Contribution of Peroxisomes to Secondary Metabolism and Pathogenicity in the Fungal Plant Pathogen Alternaria alternata , 2010, Eukaryotic Cell.
[28] J. François,et al. Characterization of the family GH54 α-l-arabinofuranosidases in Penicillium funiculosum, including a novel protein bearing a cellulose-binding domain , 2010, Applied Microbiology and Biotechnology.
[29] T. Nonaka,et al. Hidden Function of Catalytic Domain in 6-Methylsalicylic Acid Synthase for Product Release* , 2010, The Journal of Biological Chemistry.
[30] I. Fujii. Functional analysis of fungal polyketide biosynthesis genes , 2010, The Journal of Antibiotics.
[31] Fang Zhou,et al. Cloning and expression of a cellulase gene in the silkworm, Bombyx mori by improved Bac-to-Bac/BmNPV baculovirus expression system , 2010, Molecular Biology Reports.
[32] K. Imamura,et al. Cultivation characteristics and gene expression profiles of Aspergillus oryzae by membrane-surface liquid culture, shaking-flask culture, and agar-plate culture. , 2010, Journal of bioscience and bioengineering.
[33] K. Kitamoto,et al. Promotion of Efficient Saccharification of Crystalline Cellulose by Aspergillus fumigatus Swo1 , 2010, Applied and Environmental Microbiology.
[34] Clay C C Wang,et al. Molecular genetic analysis of the orsellinic acid/F9775 gene cluster of Aspergillus nidulans. , 2010, Molecular bioSystems.
[35] Carlos García-Estrada,et al. Proteome Analysis of the Penicillin Producer Penicillium chrysogenum , 2010, Molecular & Cellular Proteomics.
[36] Clay C C Wang,et al. Characterization of the Aspergillus nidulans Monodictyphenone Gene Cluster , 2010, Applied and Environmental Microbiology.
[37] F. Armstrong,et al. Designer laccases: a vogue for high-potential fungal enzymes? , 2010, Trends in biotechnology.
[38] R. Chávez,et al. Evaluation of properties of several cheese-ripening fungi for potential biotechnological applications , 2010 .
[39] J. Eyzaguirre,et al. Proteomic analysis in non-denaturing condition of the secretome reveals the presence of multienzyme complexes in Penicillium purpurogenum , 2010, Applied Microbiology and Biotechnology.
[40] J. Oliveira,et al. Proteomics of industrial fungi: trends and insights for biotechnology , 2010, Applied Microbiology and Biotechnology.
[41] B. Seiboth,et al. Heterologous expression of an Agaricus meleagris pyranose dehydrogenase-encoding gene in Aspergillus spp. and characterization of the recombinant enzyme , 2010, Applied Microbiology and Biotechnology.
[42] Jamie H. D. Cate,et al. Systems analysis of plant cell wall degradation by the model filamentous fungus Neurospora crassa , 2009, Proceedings of the National Academy of Sciences.
[43] Marten Veenhuis,et al. An Engineered Yeast Efficiently Secreting Penicillin , 2009, PloS one.
[44] M. Linder,et al. Hydrophobin Fusions for High-Level Transient Protein Expression and Purification in Nicotiana benthamiana1[W][OA] , 2009, Plant Physiology.
[45] E. Record,et al. Heterologous production of the Piromyces equi cinnamoyl esterase in Trichoderma reesei for biotechnological applications , 2009, Letters in applied microbiology.
[46] Jie Zhang,et al. Heterologous production of non-ribosomal peptide LLD-ACV in Saccharomyces cerevisiae. , 2009, Metabolic engineering.
[47] Ruchika Sharma,et al. Approaches for refining heterologous protein production in filamentous fungi , 2009 .
[48] Ashraf S. Ibrahim,et al. Genomic Analysis of the Basal Lineage Fungus Rhizopus oryzae Reveals a Whole-Genome Duplication , 2009, PLoS genetics.
[49] D. Jacobson,et al. Vaccine production in Neurospora crassa. , 2009, Biologicals : journal of the International Association of Biological Standardization.
[50] T. Boller,et al. Innate Immunity in Plants: An Arms Race Between Pattern Recognition Receptors in Plants and Effectors in Microbial Pathogens , 2009, Science.
[51] A. Demain,et al. Production of recombinant proteins by microbes and higher organisms. , 2009, Biotechnology advances.
[52] S. Hisamatsu,et al. Metabolism of hydroxylated PCB congeners by cloned laccase isoforms , 2009, Applied Microbiology and Biotechnology.
[53] H. Döhren. A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans , 2009 .
[54] D. Archer,et al. Genomics of protein folding in the endoplasmic reticulum, secretion stress and glycosylation in the aspergilli , 2009 .
[55] Justin Powlowski,et al. Analytical and computational approaches to define the Aspergillus niger secretome. , 2009, Fungal genetics and biology : FG & B.
[56] J. Pronk,et al. Engineering of Penicillium chrysogenum for fermentative production of a novel carbamoylated cephem antibiotic precursor. , 2009, Metabolic engineering.
[57] Johannes A Roubos,et al. Effective lead selection for improved protein production in Aspergillus niger based on integrated genomics. , 2009, Fungal genetics and biology : FG & B.
[58] Jay D Keasling,et al. Developing Aspergillus as a host for heterologous expression. , 2009, Biotechnology advances.
[59] Arnold L. Demain,et al. Biosolutions to the energy problem , 2009, Journal of Industrial Microbiology & Biotechnology.
[60] Wenjun Zhang,et al. Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli , 2008, Proceedings of the National Academy of Sciences.
[61] F. Schuren,et al. Characterization of the Aspergillus niger prtT, a unique regulator of extracellular protease encoding genes. , 2008, Fungal genetics and biology : FG & B.
[62] Clay C C Wang,et al. Identification and Characterization of the Asperthecin Gene Cluster of Aspergillus nidulans , 2008, Applied and Environmental Microbiology.
[63] Andriy Kovalchuk,et al. Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum , 2008, Nature Biotechnology.
[64] Proteomics analysis of “Rovabio™ Excel”, a secreted protein cocktail from the filamentous fungus Penicillium funiculosum grown under industrial process fermentation , 2008, Journal of Industrial Microbiology & Biotechnology.
[65] A. Goffeau,et al. Outwitting Multidrug Resistance to Antifungals , 2008, Science.
[66] Zinan Wang,et al. Protoplast formation, regeneration and transformation from the taxol-producing fungus Ozonium sp . , 2008 .
[67] Isaac Y. Ho,et al. Corrigendum: Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina) , 2008, Nature Biotechnology.
[68] Motoyuki Shimizu,et al. Proteomic and metabolomic analyses of the white-rot fungus Phanerochaete chrysosporium exposed to exogenous benzoic acid. , 2008, Journal of proteome research.
[69] O. Singh,et al. Bioconversion of lignocellulosic biomass: biochemical and molecular perspectives , 2008, Journal of Industrial Microbiology & Biotechnology.
[70] Vera Meyer,et al. Genetic engineering of filamentous fungi--progress, obstacles and future trends. , 2008, Biotechnology advances.
[71] M. Braaksma,et al. Aspergillus as a cell factory for protein production: controlling protease activity in fungal production , 2008 .
[72] Bernard Henrissat,et al. Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina) , 2008, Nature Biotechnology.
[73] T. Gerngross,et al. N-Glycan Modification in Aspergillus Species , 2007, Applied and Environmental Microbiology.
[74] Gustavo H. Goldman,et al. The aspergilli: genomics, medical aspects, biotechnology, and research methods. , 2007 .
[75] C. Kubicek,et al. The d‐xylose reductase of Hypocrea jecorina is the major aldose reductase in pentose and d‐galactose catabolism and necessary for β‐galactosidase and cellulase induction by lactose , 2007, Molecular microbiology.
[76] J. Shiloach,et al. Expression of human α1-proteinase inhibitor in Aspergillus niger , 2007, Microbial cell factories.
[77] Christina A. Cuomo,et al. The Fusarium graminearum Genome Reveals a Link Between Localized Polymorphism and Pathogen Specialization , 2007, Science.
[78] Mark R Marten,et al. Proteomics of filamentous fungi. , 2007, Trends in biotechnology.
[79] Christina A. Cuomo,et al. Comparative proteomics of extracellular proteins in vitro and in planta from the pathogenic fungus Fusarium graminearum , 2007, Proteomics.
[80] Clay C C Wang,et al. Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi. , 2007, Journal of the American Chemical Society.
[81] C. Walsh,et al. Terrequinone A biosynthesis through L-tryptophan oxidation, dimerization and bisprenylation , 2007, Nature Chemical Biology.
[82] K. Tang,et al. Transformation of taxol-producing endophytic fungi by restriction enzyme-mediated integration (REMI). , 2007, FEMS microbiology letters.
[83] P. Covello,et al. Primary Structure, Regioselectivity, and Evolution of the Membrane-bound Fatty Acid Desaturases of Claviceps purpurea* , 2007, Journal of Biological Chemistry.
[84] Taisuke Watanabe,et al. Double disruption of the proteinase genes, tppA and pepE, increases the production level of human lysozyme by Aspergillus oryzae , 2007, Applied Microbiology and Biotechnology.
[85] M. Goto. Protein O-Glycosylation in Fungi: Diverse Structures and Multiple Functions , 2007, Bioscience, biotechnology, and biochemistry.
[86] J. Vehmaanperä,et al. Production in Trichoderma reesei of three xylanases from Chaetomium thermophilum: a recombinant thermoxylanase for biobleaching of kraft pulp , 2007, Applied Microbiology and Biotechnology.
[87] N. Talbot,et al. Functional analysis of lipid metabolism in Magnaporthe grisea reveals a requirement for peroxisomal fatty acid beta-oxidation during appressorium-mediated plant infection. , 2007, Molecular plant-microbe interactions : MPMI.
[88] P. Punt,et al. ORIGINAL RESEARCH: A dedicated vector for efficient library construction and high throughput screening in the hyphal fungus Chrysosporium lucknowense , 2007 .
[89] Corinna Lange,et al. Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans. , 2007, Nature chemical biology.
[90] G. Macino,et al. Quelling: post-transcriptional gene silencing guided by small RNAs in Neurospora crassa. , 2007, Current opinion in microbiology.
[91] A. Glieder,et al. Engineering primary metabolic pathways of industrial micro-organisms. , 2007, Journal of biotechnology.
[92] Kiyoshi Asai,et al. Genomics of Aspergillus oryzae , 2007, Bioscience, biotechnology, and biochemistry.
[93] R. Tan,et al. Involvement of nitric oxide in cerebroside-induced defense responses and taxol production in Taxus yunnanensis suspension cells , 2007, Applied Microbiology and Biotechnology.
[94] N. Lindner,et al. Increased heterologous protein production by Saccharomyces cerevisiae growing on ethanol as sole carbon source , 2007, Biotechnology and bioengineering.
[95] J. A. Roubos,et al. Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88 , 2007, Nature Biotechnology.
[96] E. Sakuradani,et al. Identification of a novel bifunctional Δ12/Δ15 fatty acid desaturase from a basidiomycete, Coprinus cinereus TD#822‐2 , 2007 .
[97] O. Akita,et al. Gene Silencing by RNA Interference in the Koji Mold Aspergillus oryzae , 2007, Bioscience, biotechnology, and biochemistry.
[98] G. Deepe,et al. Advances in combating fungal diseases: vaccines on the threshold , 2007, Nature Reviews Microbiology.
[99] U. Reichard,et al. Characterization of an extracellular subtilisin protease of Rhizopus microsporus and evidence for its expression during invasive rhinoorbital mycosis. , 2006, Medical mycology.
[100] Takashi Yoshida,et al. In Vivo Expression of UDP-N-Acetylglucosamine: α-3-D-Mannoside β-1,2-N-Acetylglucosaminyltransferase I (GnT-1) in Aspergillus oryzae and Effects on the Sugar Chain of α-Amylase , 2006 .
[101] Daniel W. Udwary,et al. Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase , 2006, Proceedings of the National Academy of Sciences.
[102] Lin Xu,et al. A complete protein pattern of cellulase and hemicellulase genes in the filamentous fungus Trichoderma reesei. , 2006, Biotechnology journal.
[103] H. Rahbek-Nielsen,et al. Increased production of chymosin by glycosylation. , 2006, Journal of biotechnology.
[104] Christopher M. Crew,et al. A high-throughput gene knockout procedure for Neurospora reveals functions for multiple transcription factors , 2006, Proceedings of the National Academy of Sciences.
[105] N. Talbot,et al. Peroxisomal carnitine acetyl transferase is required for elaboration of penetration hyphae during plant infection by Magnaporthe grisea , 2006, Molecular microbiology.
[106] J. Tomb,et al. Identification of bifunctional Δ12/ω3 fatty acid desaturases for improving the ratio of ω3 to ω6 fatty acids in microbes and plants , 2006 .
[107] U. Stahl,et al. Application of hammerhead ribozymes in filamentous fungi. , 2006, Journal of microbiological methods.
[108] K. Tang,et al. An endophytic Taxol-producing fungus BT2 isolated from Taxus chinensis var. mairei , 2006 .
[109] Osamu Akita,et al. Proteomic Analysis of Extracellular Proteins from Aspergillus oryzae Grown under Submerged and Solid-State Culture Conditions , 2006, Applied and Environmental Microbiology.
[110] S. Arai,et al. Extracellular Production of Neoculin, a Sweet-Tasting Heterodimeric Protein with Taste-Modifying Activity, by Aspergillus oryzae , 2006, Applied and Environmental Microbiology.
[111] T. Walsh,et al. Current approaches to diagnosis and treatment of invasive aspergillosis. , 2006, American journal of respiratory and critical care medicine.
[112] B. Golding,et al. Recombinant human alpha-1 proteinase inhibitor: towards therapeutic use , 2006, Amino Acids.
[113] K. Isono,et al. Genome sequencing and analysis of Aspergillus oryzae , 2005, Nature.
[114] A. Singh,et al. Culture-Based Strategies for Reduction of Protease Activity in Filtrates from Aspergillus niger NRRL-3 , 2005 .
[115] Owen P. Ward,et al. Omega-3/6 fatty acids: Alternative sources of production , 2005 .
[116] Christina A. Cuomo,et al. Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae , 2005, Nature.
[117] L. H. Grimm,et al. Morphology and productivity of filamentous fungi , 2005, Applied Microbiology and Biotechnology.
[118] Merja Penttilä,et al. Transcriptional regulation of plant cell wall degradation by filamentous fungi. , 2005, FEMS microbiology reviews.
[119] K. Shirasu,et al. The arms race continues: battle strategies between plants and fungal pathogens. , 2005, Current opinion in microbiology.
[120] D. Paul,et al. Suicidal genetically engineered microorganisms for bioremediation: need and perspectives. , 2005, BioEssays : news and reviews in molecular, cellular and developmental biology.
[121] T. Gu,et al. Bioprocessing strategies to improve heterologous protein production in filamentous fungal fermentations. , 2005, Biotechnology advances.
[122] T. Hammond,et al. RNA Silencing in Aspergillus nidulans Is Independent of RNA-Dependent RNA Polymerases , 2005, Genetics.
[123] R. Ray. Microbial Biotechnology in Agriculture and Aquaculture, Vol. 1 , 2005 .
[124] M. Davis,et al. ThehapC gene ofAspergillus nidulans is involved in the expression of CCAAT-containing promoters , 1996, Molecular and General Genetics MGG.
[125] D. Mackenzie,et al. Transcriptional and post-transcriptional events affect the production of secreted hen egg white lysozyme byAspergillus niger , 1994, Transgenic Research.
[126] J. Martín. Clusters of genes for the biosynthesis of antibiotics: Regulatory genes and overproduction of pharmaceuticals , 1992, Journal of Industrial Microbiology.
[127] Ashutosh Kumar Singh,et al. Physiology and Biotechnology of Aspergillus. , 2005, Advances in applied microbiology.
[128] G. Turner,et al. A rapid method for promoter exchange in Aspergillus nidulans using recombinant PCR. , 2005, Fungal genetics and biology : FG & B.
[129] T. Gerngross,et al. Advances in the production of human therapeutic proteins in yeasts and filamentous fungi , 2004, Nature Biotechnology.
[130] P. Dyer,et al. From genomics to post-genomics in Aspergillus. , 2004, Current opinion in microbiology.
[131] Katherine H. Huang,et al. Genome sequence of the lignocellulose degrading fungus Phanerochaete chrysosporium strain RP78 , 2004, Nature Biotechnology.
[132] Osamu Akita,et al. Transcriptional analysis of genes for energy catabolism and hydrolytic enzymes in the filamentous fungus Aspergillus oryzae using cDNA microarrays and expressed sequence tags , 2004, Applied Microbiology and Biotechnology.
[133] Linda L. Lasure,et al. Identification of Genes Associated with Morphology in Aspergillus niger by Using Suppression Subtractive Hybridization , 2004, Applied and Environmental Microbiology.
[134] M. James,et al. The molecular structure and catalytic mechanism of a novel carboxyl peptidase from Scytalidium lignicolum. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[135] Stephen G Oliver,et al. Use of expressed sequence tag analysis and cDNA microarrays of the filamentous fungus Aspergillus nidulans. , 2004, Fungal genetics and biology : FG & B.
[136] P. Suadicani,et al. Molds in floor dust and building-related symptoms in adolescent school children. , 2004, Indoor air.
[137] Takashi Yoshida,et al. Filamentous fungus Aspergillus oryzae has two types of α-1,2-mannosidases, one of which is a microsomal enzyme that removes a single mannose residue from Man9GlcNAc2 , 2000, Glycoconjugate Journal.
[138] Y. Elad,et al. The Role of Trichoderma harzianum Protease in the Biocontrol of Botrytis cinerea , 1999, European Journal of Plant Pathology.
[139] G. Weber,et al. The peptide synthetase catalyzing cyclosporine production in Tolypocladium niveum is encoded by a giant 45.8-kilobase open reading frame , 1994, Current Genetics.
[140] P. Sharp,et al. Codon usage in Aspergillus nidulans , 1991, Molecular and General Genetics MGG.
[141] V. Kauppinen,et al. Formation and release of cellulolytic enzymes during growth of Trichoderma reesei on cellobiose and glycerol , 1979, European journal of applied microbiology and biotechnology.
[142] Gary E. Harman,et al. Trichoderma species — opportunistic, avirulent plant symbionts , 2004, Nature Reviews Microbiology.
[143] R. Contreras,et al. Filamentous fungi as production organisms for glycoproteins of bio-medical interest , 2004, Glycoconjugate Journal.
[144] J. Martín,et al. Expression of the penDE gene of Penicillium chrysogenum encoding isopenicillin N acyltransferase in Cephalosporium acremonium: production of benzylpenicillin by the transformants , 2004, Molecular and General Genetics MGG.
[145] O. Fawole,et al. Some factors affecting production of pectic enzymes by Aspergillus niger , 2003 .
[146] Tingyue Gu,et al. Effects of process parameters on heterologous protein production in Aspergillus niger fermentation , 2003 .
[147] R. Murphy,et al. Cloning and expression of fungal phytases in genetically modified strains of Aspergillus awamori , 2003, Journal of Industrial Microbiology and Biotechnology.
[148] H. Noorman,et al. Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Growth yields and morphological characterization. , 2003, Biotechnology and bioengineering.
[149] J. Cherry,et al. Directed evolution of industrial enzymes: an update. , 2003, Current opinion in biotechnology.
[150] P. W. V. van Dijck,et al. On the safety of a new generation of DSM Aspergillus niger enzyme production strains. , 2003, Regulatory toxicology and pharmacology : RTP.
[151] Chulong Zhang,et al. [Recent research and prospect on taxol and its producing fungi]. , 2003, Wei sheng wu xue bao = Acta microbiologica Sinica.
[152] J. Liu,et al. Improving heterologous gene expression in Aspergillus niger by introducing multiple copies of protein‐binding sequence containing CCAAT to the promoter , 2003, Letters in applied microbiology.
[153] E. Mauceli,et al. The genome sequence of the filamentous fungus Neurospora crassa , 2003, Nature.
[154] Ben Shen,et al. Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms. , 2003, Current opinion in chemical biology.
[155] T. Zank,et al. Metabolic engineering of fatty acids for breeding of new oilseed crops: strategies, problems and first results. , 2003, Journal of plant physiology.
[156] R. D. de Vries. Regulation of Aspergillus genes encoding plant cell wall polysaccharide-degrading enzymes; relevance for industrial production , 2003, Applied microbiology and biotechnology.
[157] H. Noorman,et al. Influence of the adipate and dissolved oxygen concentrations on the beta-lactam production during continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus. , 2003, Metabolic engineering.
[158] Monika Schmoll,et al. Regulation of Trichoderma cellulase formation: lessons in molecular biology from an industrial fungus. A review. , 2003, Acta microbiologica et immunologica Hungarica.
[159] R. D. Vries. Regulation of Aspergillus genes encoding plant cell wall polysaccharide-degrading enzymes; relevance for industrial production , 2003, Applied Microbiology and Biotechnology.
[160] K. Iwashita,et al. Recent studies of protein secretion by filamentous fungi. , 2002, Journal of bioscience and bioengineering.
[161] J. Martín,et al. Silencing of the Aspergillopepsin B (pepB) Gene of Aspergillus awamori by Antisense RNA Expression or Protease Removal by Gene Disruption Results in a Large Increase in Thaumatin Production , 2002, Applied and Environmental Microbiology.
[162] O. Akita,et al. Subtractive cloning of cDNA from Aspergillus oryzae differentially regulated between solid-state culture and liquid (submerged) culture , 2002, Current Genetics.
[163] M. Moo-young,et al. Protease secretion in glucoamylase producer Aspergillus niger cultures: fungal morphology and inoculum effects , 2002 .
[164] P. Covello,et al. High-Level Production of γ-Linolenic Acid in Brassica juncea Using a Δ6 Desaturase from Pythium irregulare , 2002, Plant Physiology.
[165] W. D. de Vos,et al. Aspergillus oryzae in solid-state and submerged fermentations. Progress report on a multi-disciplinary project. , 2002, FEMS yeast research.
[166] Ana Conesa,et al. Filamentous fungi as cell factories for heterologous protein production. , 2002, Trends in biotechnology.
[167] U. Reichard,et al. Molecular cloning of an extracellular aspartic proteinase from Rhizopus microsporus and evidence for its expression during infection. , 2002, Medical mycology.
[168] M. Machida. Progress of Aspergillus oryzae genomics. , 2002, Advances in applied microbiology.
[169] S. Zeilinger,et al. Regulation of gene expression in industrial fungi: Trichoderma , 2002, Applied Microbiology and Biotechnology.
[170] J. Frisvad,et al. On the safety of Aspergillus niger – a review , 2002, Applied Microbiology and Biotechnology.
[171] D. Hawksworth. The magnitude of fungal diversity: the 1.5 million species estimate revisited * * Paper presented at , 2001 .
[172] Y. Hata,et al. Establishment of a hyper-protein production system in submerged Aspergillus oryzae culture under tyrosinase-encoding gene (melO) promoter control , 2001, Applied Microbiology and Biotechnology.
[173] H. Noorman,et al. Physiological characterisation of Penicillium chrysogenum strains expressing the expandase gene from Streptomyces clavuligerus during batch cultivations. Growth and adipoyl-7-aminodeacetoxycephalosporanic acid production. , 2001, Applied Microbiology and Biotechnology.
[174] T. Gu,et al. Enhanced heterologous protein production in Aspergillus niger through pH control of extracellular protease activity , 2001 .
[175] A. Conesa,et al. The secretion pathway in filamentous fungi: a biotechnological view. , 2001, Fungal genetics and biology : FG & B.
[176] F. Tjerneld,et al. Genetic engineering of the Trichoderma reesei endoglucanase I (Cel7B) for enhanced partitioning in aqueous two-phase systems containing thermoseparating ethylene oxide--propylene oxide copolymers. , 2001, Journal of biotechnology.
[177] A. Conesa. Overproduction of fungal peroxidases in filamentous fungi , 2001 .
[178] V. Ziboh,et al. Evaluation of the seed oils from a canola plant genetically transformed to produce high levels of γ-linolenic acid. , 2001 .
[179] Y. Huang,et al. γ-linolenic acid : recent advances in biotechnology and clinical applications , 2001 .
[180] A. T. Carter,et al. Isolation and Use of a Homologous Histone H4 Promoter and a Ribosomal DNA Region in a Transformation Vector for the Oil-Producing Fungus Mortierella alpina , 2000, Applied and Environmental Microbiology.
[181] J. Nielsen,et al. Antisense Silencing of the creA Gene inAspergillus nidulans , 2000, Applied and Environmental Microbiology.
[182] G. Robson,et al. A glucoamylase::GFP gene fusion to study protein secretion by individual hyphae of Aspergillus niger. , 2000, Journal of microbiological methods.
[183] J. Sekiguchi,et al. Cloning and sequencing of the triacylglycerol lipase gene of Aspergillus oryzae and its expression in Escherichia coli. , 2000, FEMS microbiology letters.
[184] A. Conesa,et al. Studies on the Production of Fungal Peroxidases inAspergillus niger , 2000, Applied and Environmental Microbiology.
[185] S. H. Denison. pH regulation of gene expression in fungi. , 2000, Fungal genetics and biology : FG & B.
[186] P. Punt,et al. Characterization of a Foldase, Protein Disulfide Isomerase A, in the Protein Secretory Pathway ofAspergillus niger , 2000, Applied and Environmental Microbiology.
[187] E. Vroom,et al. Innovations in cephalosporin and penicillin production : Painting the antibiotics industry green , 2000 .
[188] J. Norelli,et al. Expression of Endochitinase from Trichoderma harzianum in Transgenic Apple Increases Resistance to Apple Scab and Reduces Vigor. , 2000, Phytopathology.
[189] K. Kitamoto,et al. Production and product quality assessment of human hepatitis B virus pre-S2 antigen in submerged and solid-state cultures of Aspergillus oryzae. , 2000, Journal of bioscience and bioengineering.
[190] T. Gu,et al. Increased Heterologous Protein Production in Aspergillusniger Fermentation through Extracellular Proteases Inhibition by Pelleted Growth , 2000, Biotechnology progress.
[191] E. Sakuradani,et al. Δ6-Fatty acid desaturase from an arachidonic acid-producing Mortierella fungus , 1999 .
[192] M. Kobayashi,et al. Delta6-fatty acid desaturase from an arachidonic acid-producing Mortierella fungus. Gene cloning and its heterologous expression in a fungus, Aspergillus. , 1999, Gene.
[193] Sunita Chaudhary,et al. Cloning of Δ12- and Δ6-desaturases from Mortierella alpina and recombinant production of γ-linolenic acid in Saccharomyces cerevisiae , 1999, Lipids.
[194] R. Contreras,et al. In vivo synthesis of complex N‐glycans by expression of human N‐acetylglucosaminyltransferase I in the filamentous fungus Trichoderma reesei , 1999, FEBS letters.
[195] J. Vederas,et al. Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis. , 1999, Science.
[196] Koji Takahashi,et al. Molecular and enzymic properties of recombinant 1, 2-alpha-mannosidase from Aspergillus saitoi overexpressed in Aspergillus oryzae cells. , 1999, The Biochemical journal.
[197] D. Haynie,et al. Determinants of the fidelity of processing glucoamylase-lysozyme fusions by Aspergillus niger. , 1998, European journal of biochemistry.
[198] Yung-Sheng Huang,et al. Identification of Δ5-Desaturase from Mortierella alpina by Heterologous Expression in Bakers’ Yeast and Canola* , 1998, The Journal of Biological Chemistry.
[199] G. Robson,et al. Recombinant glucoamylase production by Aspergillus niger B1 in chemostat and pH auxostat cultures. , 1998, Fungal genetics and biology : FG & B.
[200] K. Takahashi,et al. Improvement of promoter activity by the introduction of multiple copies of the conserved region III sequence, involved in the efficient expression of Aspergillus oryzae amylase-encoding genes , 1998, Applied Microbiology and Biotechnology.
[201] T. Komiyama,et al. Aberrant processing of wild-type and mutant bovine pancreatic trypsin inhibitor secreted by Aspergillus niger. , 1998, Journal of biotechnology.
[202] A. Stobart,et al. Isolation of a Δ5-Fatty Acid Desaturase Gene fromMortierella alpina * , 1998, The Journal of Biological Chemistry.
[203] C. Lawrence,et al. Genes from mycoparasitic fungi as a source for improving plant resistance to fungal pathogens. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[204] P. Barr,et al. Production of a polyketide natural product in nonpolyketide-producing prokaryotic and eukaryotic hosts. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[205] Merja Penttilä,et al. Heterologous protein production in Trichoderma , 1998 .
[206] P. Punt,et al. Analysis of the role of the gene bipA, encoding the major endoplasmic reticulum chaperone protein in the secretion of homologous and heterologous proteins in black Aspergilli , 1998, Applied Microbiology and Biotechnology.
[207] M. Takeuchi,et al. Construction of a low-serine-type-carboxypeptidase-producing mutant of Aspergillus oryzae by the expression of antisense RNA and its use as a host for heterologous protein secretion , 1998, Applied Microbiology and Biotechnology.
[208] R. Contreras,et al. In vitro conversion of the carbohydrate moiety of fungal glycoproteins to mammalian-type oligosaccharides--evidence for N-acetylglucosaminyltransferase-I-accepting glycans from Trichoderma reesei. , 1997, European journal of biochemistry.
[209] P. Punt,et al. The ER chaperone encoding bipA gene of black Aspergilli is induced by heat shock and unfolded proteins. , 1997, Gene.
[210] U. Kück,et al. Synthesis of biotechnologically relevant heterologous proteins in filamentous fungi , 1997 .
[211] D. Jeenes,et al. Isolation and characterisation of a novel stress-inducible PDI-family gene from Aspergillus niger. , 1997, Gene.
[212] J. Visser,et al. Aspergillus as a host for heterologous protein production: the problem of proteases. , 1997, Trends in biotechnology.
[213] A. Clutterbuck. The Validity of theAspergillus nidulansLinkage Map , 1997 .
[214] J·莱姆比克. Alkaline protease deficient filamentous fungi , 1997 .
[215] J. Visser,et al. Overexpression of phosphofructokinase and pyruvate kinase in citric acid-producing Aspergillus niger. , 1997, Biochimica et biophysica acta.
[216] D. Cullen,et al. Recent advances on the molecular genetics of ligninolytic fungi. , 1997, Journal of biotechnology.
[217] P. Punt,et al. Glucoamylase gene fusions alleviate limitations for protein production in Aspergillus awamori at the transcriptional and (post) translational levels , 1997, Applied and environmental microbiology.
[218] P. Punt,et al. Efficient production of secreted proteins by Aspergillus : progress, limitations and prospects , 1997, Applied Microbiology and Biotechnology.
[219] M. Kobayashi,et al. Screening of novel microbial enzymes for the production of biologically and chemically useful compounds. , 1997, Advances in biochemical engineering/biotechnology.
[220] A. Clutterbuck. The validity of the Aspergillus nidulans linkage map. , 1997, Fungal genetics and biology : FG & B.
[221] E O Voit,et al. Optimization of nonlinear biotechnological processes with linear programming: Application to citric acid production by Aspergillus niger , 2000, Biotechnology and bioengineering.
[222] T. Stachelhaus,et al. Engineered biosynthesis of peptide antibiotics. , 1996, Biochemical pharmacology.
[223] R. S. St. Leger,et al. Construction of an improved mycoinsecticide overexpressing a toxic protease. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[224] John E. Linz,et al. Demonstration of the catalytic roles and evidence for the physical association of type I fatty acid synthases and a polyketide synthase in the biosynthesis of aflatoxin B1. , 1996, Chemistry & biology.
[225] M. Tien,et al. Efficient expression of a Phanerochaete chrysosporium manganese peroxidase gene in Aspergillus oryzae , 1996, Applied and environmental microbiology.
[226] C. Khosla,et al. Expression of a functional fungal polyketide synthase in the bacterium Streptomyces coelicolor A3(2) , 1995, Journal of bacteriology.
[227] O. Conneely,et al. A System for Production of Commercial Quantities of Human Lactoferrin: A Broad Spectrum Natural Antibiotic , 1995, Bio/Technology.
[228] T. Stachelhaus,et al. Modular structure of genes encoding multifunctional peptide synthetases required for non-ribosomal peptide synthesis. , 1995, FEMS microbiology letters.
[229] V. Vinci,et al. Production of Cephalosporin Intermediates by Feeding Adipic Acid to Recombinant Penicillium chrysogenum Strains Expressing Ring Expansion Activity , 1995, Bio/Technology.
[230] C. Kubicek,et al. Parallel formation and synergism of hydrolytic enzymes and peptaibol antibiotics, molecular mechanisms involved in the antagonistic action of Trichoderma harzianum against phytopathogenic fungi , 1994, Applied and environmental microbiology.
[231] H. Nevalainen,et al. On the safety of Trichoderma reesei. , 1994, Journal of biotechnology.
[232] K. Kitamoto,et al. Electrophoretic karyotype and gene assignment to chromosomes of Aspergillus oryzae. , 1994, Bioscience, biotechnology, and biochemistry.
[233] K. Kitamoto,et al. High level secretion of calf chymosin using a glucoamylase-prochymosin fusion gene in Aspergillus oryzae. , 1994, Bioscience, biotechnology, and biochemistry.
[234] 스벤 하스트룹,et al. 효소생성방법(processes for producing an enzyme) , 1994 .
[235] A. Goffeau,et al. PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. , 1994, The Journal of biological chemistry.
[236] R. Contreras,et al. Secretion of heterologous proteins by Aspergillus niger: production of active human interleukin-6 in a protease-deficient mutant by KEX2-like processing of a glucoamylase-hIL6 fusion protein. , 1993, Journal of biotechnology.
[237] A. Demain,et al. δ-(L-α-Aminoadipyl)-L-Cysteinyl-D-Valine Synthetase, the Multienzyme Integrating the Four Primary Reactions in β-Lactam Biosynthesis, as a Model Peptide Synthetase , 1993, Bio/Technology.
[238] S. Logemann,et al. Increased Constitutive Chitinase Activity in Transformed Trichoderma harzianum , 1993 .
[239] M. Montagu,et al. Molecular characterization of the proteinase‐encoding gene, prb1, related to mycoparasitism by Trichoderma harzianum , 1993, Molecular microbiology.
[240] M. Penttilä,et al. Efficient Production of Antibody Fragments by the Filamentous Fungus Trichoderma reesei , 1993, Bio/Technology.
[241] D. Mackenzie,et al. A truncated glucoamylase gene fusion for heterologous protein secretion from Aspergillus niger. , 1993, FEMS microbiology letters.
[242] O. Conneely,et al. An inducible expression system for the production of human lactoferrin in Aspergillus nidulans. , 1992, Gene.
[243] I. Roberts,et al. Heterologous gene expression in Aspergillus niger: a glucoamylase-porcine pancreatic prophospholipase A2 fusion protein is secreted and processed to yield mature enzyme. , 1992, Gene.
[244] M. Marahiel. Multidomain enzymes involved in peptide synthesis , 1992, FEBS letters.
[245] A. Verkleij,et al. Involvement of microbodies in penicillin biosynthesis. , 1992, Biochimica et biophysica acta.
[246] S. Covert,et al. Heterologous Protein Expression in Filamentous Fungi , 1992 .
[247] D. Gwynne,et al. Expression of foreign proteins in the genus Aspergillus. , 1992, Biotechnology.
[248] R. Berka,et al. Commercial Levels of Chymosin Production by Aspergillus , 1991, Bio/Technology.
[249] R. Crystal,et al. Use of a Highly Purified α1-Antitrypsin Standard to Establish Ranges for the Common Normal and Deficient α1-Antitrypsin Phenotypes , 1991 .
[250] A. Cuticchia,et al. Chromosome-specific recombinant DNA libraries from the fungus Aspergillus nidulans. , 1991, Nucleic acids research.
[251] A. Verkleij,et al. Localization of the pathway of the penicillin biosynthesis in Penicillium chrysogenum. , 1991, The EMBO journal.
[252] M. Penttilä,et al. Enzyme production by recombinant Trichoderma reesei strains. , 1991, Journal of biotechnology.
[253] G. Turner,et al. The multifunctional peptide synthetase performing the first step of penicillin biosynthesis in Penicillium chrysogenum is a 421,073 dalton protein similar to Bacillus brevis peptide antibiotic synthetases. , 1990, The EMBO journal.
[254] C. Dobson,et al. Hen Egg White Lysozyme Expressed in, and Secreted from, Aspergillus niger is Correctly Processed and Folded , 1990, Bio/Technology.
[255] R. Berka,et al. Improved Production of Chymosin in Aspergillus by Expression as a Glucoamylase-Chymosin Fusion , 1990, Bio/Technology.
[256] H. Döhren,et al. Review Nonribosomal biosynthesis of peptide antibiotics , 1990 .
[257] N. Benhamou,et al. Cytochemical aspects of chitin breakdown during the parasitic action of a Trichoderma sp. on Fusarium oxysporum f.sp. radicis-lycopersici. , 1990 .
[258] M. Penttilä,et al. A Novel Fungal Expression System: Secretion of Active Calf Chymosin from the Filamentous Fungus Trichoderma Reesei , 1989, Bio/Technology.
[259] P. Liras,et al. Organization and expression of genes involved in the biosynthesis of antibiotics and other secondary metabolites. , 1989, Annual review of microbiology.
[260] L. Thim,et al. High Level Expression of Recombinant Genes in Aspergillus Oryzae , 1988, Bio/Technology.
[261] O. Ward. Fermentation Biotechnology: Principles, Processes and Products , 1988 .
[262] J. Heim,et al. The biosynthesis of sulfur-containing beta-lactam antibiotics. , 1987, Annual review of microbiology.
[263] R. Farrell,et al. Enzymatic "combustion": the microbial degradation of lignin. , 1987, Annual review of microbiology.
[264] M. Takeuchi,et al. A 155K Acid Carboxypeptidase O from Aspergillus oryzae , 1986 .
[265] R. Elander. Strain Improvement and Preservation of β -Lactam-Producing Microorganisms , 1983 .
[266] Frank Harary,et al. What is a System , 1981 .
[267] U. S. Army,et al. Induction of cellulolytic enzymes in Trichoderma reesei by sophorose , 1979, Journal of bacteriology.
[268] M. Taylor,et al. Applications of microbial enzymes in food systems and in biotechnology. , 1979, Advances in applied microbiology.
[269] A. H. Rose. Primary products of metabolism , 1978 .
[270] S. Nolting,et al. [Clinical mycology]. , 1978, MMW, Munchener medizinische Wochenschrift.
[271] C. Dennis,et al. ANTAGONISTIC PROPERTIES OF SPECIES- GROUPS OF TRICHODERMA: III HYPHAL INTERACTION , 1971 .
[272] P. B. Loder,et al. Isolation and nature of intracellular peptides from a cephalosporin C-producing Cephalosporium sp. , 1971, The Biochemical journal.
[273] A. McPhail,et al. Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. , 1971, Journal of the American Chemical Society.
[274] C. Dennis,et al. Antagonistic properties of species-groups of Trichoderma: I. Production of non-volatile antibiotics , 1971 .