In this work, two kinds of binders, Ammonium Zirconium Carbonate(AZC) and Ammonium Metatungstate(AMT) hydrate, and three kinds of powders(ZrO 2, Al2O3 and Y2O3) were mixed to fabricate six kinds of face coating systems. The thermal behaviors of the AZC and AMT dried binders were investigated by TG-DTA, and the phase transformation of the two binders was determined by XRD. Monoclinic ZrO 2 phase was formed from AZC at 620 °C and WO3 at 700 °C, and the phase transformation was completed at lower than 1000 °C in both binders, and therefore, the sintering temperature for the molds was selected at 950 °C. The interaction between the ceramic molds with different face coatings and the Ti-48Al-2Cr-2Nb alloy during investment casting was studied. Results showed no α-case reaction in the TiA l-mold reaction, and the AMT + Y2O3 face coating appeared to be the best choice for investment casting of TiA l alloys under the experimental conditions.