Following the tracks of AKT1 gene
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[1] Spyro Mousses,et al. A transforming mutation in the pleckstrin homology domain of AKT1 in cancer , 2007, Nature.
[2] Yuval Inbar,et al. Mechanism of Two Classes of Cancer Mutations in the Phosphoinositide 3-Kinase Catalytic Subunit , 2007, Science.
[3] P. Pavlidis,et al. Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning , 2006, Proceedings of the National Academy of Sciences.
[4] G. Parmigiani,et al. The Consensus Coding Sequences of Human Breast and Colorectal Cancers , 2006, Science.
[5] G. Hortobagyi,et al. Mechanisms of Disease: understanding resistance to HER2-targeted therapy in human breast cancer , 2006, Nature Clinical Practice Oncology.
[6] A. Toker,et al. Akt signaling and cancer: surviving but not moving on. , 2006, Cancer research.
[7] R. Memmott,et al. Handicapping the Race to Develop Inhibitors of the Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin Pathway , 2006, Clinical Cancer Research.
[8] J. Testa,et al. Perturbations of the AKT signaling pathway in human cancer , 2005, Oncogene.
[9] C. Kumar,et al. AKT crystal structure and AKT-specific inhibitors , 2005, Oncogene.
[10] Huan Yang,et al. The Akt/PKB pathway: molecular target for cancer drug discovery , 2005, Oncogene.
[11] C. Lindsley,et al. The Akt/PKB family of protein kinases: a review of small molecule inhibitors and progress towards target validation. , 2005, Current topics in medicinal chemistry.
[12] A. Kral,et al. Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors , 2022 .
[13] P. Pandolfi. Breast cancer--loss of PTEN predicts resistance to treatment. , 2004, The New England journal of medicine.
[14] J. Ptak,et al. High Frequency of Mutations of the PIK3CA Gene in Human Cancers , 2004, Science.
[15] P. Dennis,et al. Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues. , 2004, Cancer research.
[16] M. Karayiorgou,et al. Convergent evidence for impaired AKT1-GSK3β signaling in schizophrenia , 2004, Nature Genetics.
[17] G. Reifenberger,et al. Genetic Alterations and Aberrant Expression of Genes Related to the Phosphatidyl‐lnositol‐3′‐Kinase/Protein Kinase B (Akt) Signal Transduction Pathway in Glioblastomas , 2003, Brain pathology.
[18] C. Sawyers,et al. The phosphatidylinositol 3-Kinase–AKT pathway in human cancer , 2002, Nature Reviews Cancer.
[19] E. Hafen,et al. Living with Lethal PIP3 Levels: Viability of Flies Lacking PTEN Restored by a PH Domain Mutation in Akt/PKB , 2002, Science.
[20] P. Dennis,et al. Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. , 2001, Cancer research.
[21] Pier Paolo Pandolfi,et al. The Multiple Roles of PTEN in Tumor Suppression , 2000, Cell.
[22] R. Weigel,et al. Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site. , 1999, Biochemical and biophysical research communications.
[23] B. Hemmings,et al. A Human Protein Kinase Bγ with Regulatory Phosphorylation Sites in the Activation Loop and in the C-terminal Hydrophobic Domain* , 1999, The Journal of Biological Chemistry.
[24] J. Cheng,et al. Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas , 1995, International journal of cancer.
[25] Andrius Kazlauskas,et al. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase , 1995, Cell.
[26] S. Staal. Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[27] C. Croce,et al. The AKT1 proto-oncogene maps to human chromosome 14, band q32. , 1988, Genomics.