Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties.

[1]  S. Granica,et al.  Bioactive Potential: A Pharmacognostic Definition through the Screening of Four Hypericum Species from the Canary Islands , 2022, Molecules.

[2]  G. Santos,et al.  Early Pharmacological Profiling of Antiproliferative Compounds by Live Cell Imaging , 2022, Molecules.

[3]  F. Gamarro,et al.  Synthesis of sp2-Iminosugar Selenoglycolipids as Multitarget Drug Candidates with Antiproliferative, Leishmanicidal and Anti-Inflammatory Properties , 2021, Molecules.

[4]  Louis-Charles Campeau,et al.  Diversity-oriented synthesis of glycomimetics , 2021, Communications Chemistry.

[5]  F. Sbrana,et al.  Holotomographic microscopy: A new approach to detect apoptotic cell features , 2020, Microscopy research and technique.

[6]  Yan Zhang,et al.  Synthesis of 2'-paclitaxel 2-deoxy-2-fluoro-glucopyranosyl carbonate for specific targeted delivery to cancer cells. , 2020, Carbohydrate research.

[7]  N. Shibata,et al.  Contribution of Organofluorine Compounds to Pharmaceuticals , 2020, ACS omega.

[8]  C. Ortiz Mellet,et al.  Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis. , 2020, The Journal of organic chemistry.

[9]  Galen P. Miley,et al.  Inducible nitric oxide synthase: Regulation, structure, and inhibition , 2020, Medicinal research reviews.

[10]  F. Gamarro,et al.  Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapies. , 2019, European journal of medicinal chemistry.

[11]  A. Szwajca,et al.  Design, properties and applications of fluorinated and fluoroalkylated N-containing monosaccharides and their analogues , 2019, Journal of Fluorine Chemistry.

[12]  F. Gamarro,et al.  Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids , 2019, Molecules.

[13]  M. Uhrig,et al.  Synthetic strategies for fluorination of carbohydrates. , 2019, Organic & biomolecular chemistry.

[14]  C. Ortiz Mellet,et al.  sp2-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo. , 2019, European journal of medicinal chemistry.

[15]  A. Roderick,et al.  Naphthol-derived Betti bases as potential SLC6A14 blockers , 2019, Journal of Molecular and Clinical Medicine.

[16]  I. Wolf,et al.  AutoCellSeg: robust automatic colony forming unit (CFU)/cell analysis using adaptive image segmentation and easy-to-use post-editing techniques , 2018, Scientific Reports.

[17]  Laurent Knerr,et al.  Fluorine-Directed Glycosylation Enables the Stereocontrolled Synthesis of Selective SGLT2 Inhibitors for Type II Diabetes. , 2018, Chemistry.

[18]  N. Meanwell.  Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design. , 2018, Journal of medicinal chemistry.

[19]  Á. Valverde,et al.  The sp2-iminosugar glycolipid 1-dodecylsulfonyl-5N,6O-oxomethylidenenojirimycin (DSO2-ONJ) as selective anti-inflammatory agent by modulation of hemeoxygenase-1 in Bv.2 microglial cells and retinal explants. , 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[20]  G. Jiménez‐Osés,et al.  Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody. , 2016, Organic letters.

[21]  L. Tan,et al.  Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease. , 2015, Annals of translational medicine.

[22]  S. Castanys,et al.  Antileishmanial activity of sp2-iminosugar derivatives , 2015 .

[23]  Zhihong Yang,et al.  Functions of Arginase Isoforms in Macrophage Inflammatory Responses: Impact on Cardiovascular Diseases and Metabolic Disorders , 2014, Front. Immunol..

[24]  R. Talwani,et al.  Sofosbuvir for the treatment of chronic hepatitis C virus infection. , 2014, Drugs of today.

[25]  Hong Liu,et al.  Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011). , 2014, Chemical reviews.

[26]  Woody Sherman,et al.  Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments , 2013, Journal of Computer-Aided Molecular Design.

[27]  S. H. Lee,et al.  Clevudine for chronic hepatitis B: antiviral response, predictors of response, and development of myopathy , 2011, Journal of viral hepatitis.

[28]  H. Kantarjian,et al.  Clofarabine in leukemia , 2010, Expert review of hematology.

[29]  G. Charras,et al.  Death‐associated protein kinase (DAPK) and signal transduction: blebbing in programmed cell death , 2010, The FEBS journal.

[30]  Arthur J. Olson,et al.  AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading , 2009, J. Comput. Chem..

[31]  A. Moon,et al.  The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer , 2009, Expert opinion on investigational drugs.

[32]  R. Csuk,et al.  Amplification of the inhibitory activity of miglitol by monofluorination. , 2009, Bioorganic & medicinal chemistry letters.

[33]  T. Madden,et al.  D-glucose- and D-mannose-based antimetabolites. Part 2. Facile synthesis of 2-deoxy-2-halo-D-glucoses and -D-mannoses. , 2009, Carbohydrate research.

[34]  J. G. García Fernández,et al.  Synthesis of thiohydantoin-castanospermine glycomimetics as glycosidase inhibitors. , 2009, The Journal of organic chemistry.

[35]  Guillaume Charras,et al.  A short history of blebbing , 2008, Journal of microscopy.

[36]  W. Hagmann,et al.  The many roles for fluorine in medicinal chemistry. , 2008, Journal of medicinal chemistry.

[37]  C. Ortiz Mellet,et al.  Synthesis and evaluation of sulfamide-type indolizidines as glycosidase inhibitors. , 2008, Bioorganic & medicinal chemistry letters.

[38]  J. N. Sharma,et al.  Role of nitric oxide in inflammatory diseases , 2007, Inflammopharmacology.

[39]  Jiahuai Han,et al.  Phosphatidylinositol Ether Lipid Analogues That Inhibit AKT Also Independently Activate the Stress Kinase, p38α, through MKK3/6-independent and -dependent Mechanisms* , 2007, Journal of Biological Chemistry.

[40]  Andrew D Westwell,et al.  The role of fluorine in medicinal chemistry , 2007, Journal of enzyme inhibition and medicinal chemistry.

[41]  Jun-Ming Zhang,et al.  Cytokines, Inflammation, and Pain , 2007, International anesthesiology clinics.

[42]  K. Ginalski,et al.  Efficacy of 2-halogen substituted d-glucose analogs in blocking glycolysis and killing “hypoxic tumor cells” , 2006, Cancer Chemotherapy and Pharmacology.

[43]  C. Ortiz Mellet,et al.  Synthesis and Comparative Glycosidase Inhibitory Properties of Reducing Castanospermine Analogues , 2005 .

[44]  N. Kitteringham,et al.  Metabolism of fluorine-containing drugs. , 2001, Annual review of pharmacology and toxicology.

[45]  F. Cañada,et al.  Generalized anomeric effect in action: synthesis and evaluation of stable reducing indolizidine glycomimetics as glycosidase inhibitors. , 2000, The Journal of organic chemistry.

[46]  Chi‐Huey Wong,et al.  Electrophilic Fluorination-Nucleophilic Addition Reaction Mediated by Selectfluor: Mechanistic Studies and New Applications. , 1999, The Journal of organic chemistry.

[47]  M. Chang,et al.  Synthesis and antitumor activity of the 7-O-(2,6-dideoxy-2-fluoro-α-l-talopyranosyl)daunomycinone derivatives modified at C-3′ or C-4′ , 1998 .

[48]  Chi‐Huey Wong,et al.  A New Method for the Synthesis of Fluoro-Carbohydrates and Glycosides Using Selectfluor , 1997 .

[49]  S. Withers,et al.  Hydrogen bonding and specificity. Fluorodeoxy sugars as probes of hydrogen bonding in the glycogen phosphorylase-glucose complex. , 1986, Biochemistry.

[50]  S. Tannenbaum,et al.  Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. , 1982, Analytical biochemistry.

[51]  G. Zemplén,et al.  Über die Verseifung acetylierter Zucker und verwandter Substanzen , 1929 .