Synthesis and structural studies of a new class of heterocyclic compounds: 1,2,4-Pyridothiadiazine 1,1-dioxides, pyridyl analogues of 1,2,4-benzothiadiazine 1,1-dioxides

[1]  B. Masereel,et al.  3-(Alkylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as powerful inhibitors of insulin release from rat pancreatic B-cells: a new class of potassium channel openers? , 1993, Journal of medicinal chemistry.

[2]  J. R. Weille Modulation of ATP sensitive potassium channels. , 1992 .

[3]  B. Masereel,et al.  Na+,2Cl-,K+ cotransport system as a marker of antihypertensive activity of new torasemide derivatives. , 1992, European journal of pharmacology.

[4]  R. Moquin,et al.  Benzothiadiazine dioxides: A new class of potent angiotensin-II (AT1) receptor antagonists , 1992 .

[5]  T. Hamilton,et al.  Potassium channel activator drugs: Mechanism of action, pharmacological properties, and therapeutic potential , 1992, Medicinal research reviews.

[6]  G. Edwards,et al.  Structure-activity relationships of K+ channel openers. , 1990, Trends in pharmacological sciences.

[7]  D. Robertson,et al.  Potassium channel modulators: scientific applications and therapeutic promise. , 1990, Journal of medicinal chemistry.

[8]  M. Williams,et al.  Aminomethyl-1,2,4-benzothiadiazines as potential analogues of gamma-aminobutyric acid. Unexpected discovery of a taurine antagonist. , 1982, Journal of medicinal chemistry.

[9]  J. Delarge,et al.  [Synthesis and pharmacologic properties of some N-acylsulfonamides]. , 1974, Annales pharmaceutiques francaises.

[10]  J. Sprague,et al.  Diuretics: 1,2,4-Benzothiadiazine-1,1-dioxides , 1960 .

[11]  H. L. Yale,et al.  6-(Trifluoromethyl)-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide and Related Compounds , 1960 .

[12]  J. H. Freeman,et al.  1,2,4-BENZOTHIADIAZINE DIOXIDES AND 3,4-DIHYDRO-1,2,4-BENZOTHIADIAZINE DIOXIDES1, 2 , 1951 .

[13]  D. Escande,et al.  K+ channel openers and 'natural' cardioprotection. , 1992, Trends in pharmacological sciences.

[14]  F. Ashcroft Adenosine 5'-triphosphate-sensitive potassium channels. , 1988, Annual review of neuroscience.

[15]  P. Jakobsen,et al.  The structure of 1,2,4-benzothiadiazine-1,1-dioxides , 1979 .

[16]  Andrejus Korolkovas,et al.  Essentials of Medicinal Chemistry , 1976 .

[17]  G. D. Rieck,et al.  International tables for X-ray crystallography , 1962 .