Description and prediction of peptide-MHC binding: the 'human MHC project'.

[1]  P Parham,et al.  HLA class I region sequences, 1998. , 2008, Tissue antigens.

[2]  P. Travers,et al.  The MHC class I-restricted immune response to HIV-gag in BALB/c mice selects a single epitope that does not have a predictable MHC-binding motif and binds to Kd through interactions between a glutamine at P3 and pocket D. , 1998, Journal of immunology.

[3]  C DeLisi,et al.  Structural principles that govern the peptide-binding motifs of class I MHC molecules. , 1998, Journal of molecular biology.

[4]  J. Skolnick,et al.  Application of an artificial neural network to predict specific class I MHC binding peptide sequences , 1998, Nature Biotechnology.

[5]  A Sette,et al.  A structure-based algorithm to predict potential binding peptides to MHC molecules with hydrophobic binding pockets. , 1997, Human immunology.

[6]  I. Haworth,et al.  A model of water structure inside the HLA-A2 peptide binding groove. , 1997, International immunology.

[7]  D. Margulies.  Interactions of TCRs with MHC-peptide complexes: a quantitative basis for mechanistic models. , 1997, Current opinion in immunology.

[8]  A Sette,et al.  Two complementary methods for predicting peptides binding major histocompatibility complex molecules. , 1997, Journal of molecular biology.

[9]  C DeLisi,et al.  Computational determination of side chain specificity for pockets in class I MHC molecules. , 1996, Molecular immunology.

[10]  Søren Buus,et al.  Peptide binding specificity of major histocompatibility complex class I resolved into an array of apparently independent subspecificities: quantitation by peptide libraries and improved prediction of binding , 1996, European journal of immunology.

[11]  D I Stuart,et al.  Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53. , 1996, Immunity.

[12]  S. Kienle,et al.  Amino acid preferences in the octapeptide subunit of the major histocompatibility complex class I heterotrimer H-2Ld. , 1996, European journal of biochemistry.

[13]  Stefan Kienle,et al.  Tolerance to Amino Acid Variations in Peptides Binding to the Major Histocompatibility Complex Class I Protein H-2Kb(*) , 1995, The Journal of Biological Chemistry.

[14]  H. Margalit,et al.  Ranking potential binding peptides to MHC molecules by a computational threading approach. , 1995, Journal of molecular biology.

[15]  P. A. Peterson,et al.  Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[16]  D Rognan,et al.  Molecular dynamics simulation of MHC-peptide complexes as a tool for predicting potential T cell epitopes. , 1994, Biochemistry.

[17]  A Sette,et al.  Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins. , 1994, Journal of immunology.

[18]  P. Kourilsky,et al.  Role for MHC class I molecules in selecting and protecting high affinity peptides in the presence of proteases. , 1994, Journal of immunology.

[19]  P. A. Peterson,et al.  Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. , 1994, Science.

[20]  K. Parker,et al.  Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains. , 1994, Journal of immunology.

[21]  D. Wiley,et al.  The antigenic identity of peptide-MHC complexes: A comparison of the conformations of five viral peptides presented by HLA-A2 , 1993, Cell.

[22]  J. Sidney,et al.  Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules , 1993, Cell.

[23]  D. Wiley,et al.  Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1 , 1993, Nature.

[24]  H. Grey,et al.  Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[25]  W Fierz,et al.  Using a neural network to identify potential HLA‐DR1 binding sites within proteins , 1993, Journal of molecular recognition : JMR.

[26]  R A Houghten,et al.  Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries. , 1992, BioTechniques.

[27]  Dean R. Madden,et al.  The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC , 1992, Cell.

[28]  P. A. Peterson,et al.  Emerging principles for the recognition of peptide antigens by MHC class I molecules. , 1992, Science.

[29]  H. Rammensee,et al.  Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules , 1991, Nature.

[30]  M. A. Saper,et al.  Specificity pockets for the side chains of peptide antigens in HLA-Aw68 , 1990, Nature.

[31]  H. Grey,et al.  Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[32]  P. Allen,et al.  Binding to Ia protects an immunogenic peptide from proteolytic degradation. , 1989, Journal of immunology.

[33]  M. A. Saper,et al.  The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens , 1987, Nature.

[34]  M. A. Saper,et al.  Structure of the human class I histocompatibility antigen, HLA-A2 , 1987, Nature.

[35]  H. Grey,et al.  Isolation and characterization of antigen-la complexes involved in T cell recognition , 1986, Cell.

[36]  Vladimir Brusic,et al.  Prediction of MHC class II-binding peptides using an evolutionary algorithm and artificial neural network , 1998, Bioinform..

[37]  Thomas G. Dietterich.  Adaptive computation and machine learning , 1998 .

[38]  Vladimir Brusic,et al.  MHCPEP, a database of MHC-binding peptides: update 1996 , 1997, Nucleic Acids Res..

[39]  J. Sacchettini,et al.  MHC class I-peptide interactions and TCR recognition. , 1995, Cancer surveys.

[40]  J. Berzofsky,et al.  Two novel T cell epitope prediction algorithms based on MHC-binding motifs; comparison of predicted and published epitopes from Mycobacterium tuberculosis and HIV protein sequences. , 1995, Vaccine.

[41]  J A Koziol,et al.  Prediction of binding to MHC class I molecules. , 1995, Journal of immunological methods.

[42]  R. Houghten,et al.  The use of positional scanning synthetic peptide combinatorial libraries for the rapid determination of opioid receptor ligands. , 1993, Life sciences.

[43]  J. Tamaoki,et al.  Stimulation of ciliary motility mediated by atypical beta-adrenoceptor in canine bronchial epithelium. , 1993, Life sciences.

[44]  E. Unanue,et al.  Binding of immunogenic peptides to Ia histocompatibility molecules , 1985, Nature.