Separation of Plasma Thromboplastin Antecedent (PTA) and Hageman Factor (HF) from Human Plasma.∗

Summary 1) Hageman factor and plasma thromboplastin antecedent have been separated from human plasma and each other by ion exchange chromatography. 2) The defect in “exhausted plasma” is not corrected by purified PTA, purified HF, or a combination of the two.