The purpose of the present study was to correlate the serotypes of Pseudomonas aeruginosa to the bacterial adhesion to contact lenses and human corneal epithelial cells. Twenty‐three strains isolated from contact lens wearers were used for the study. The bacterial serotypes were examined with a P. aeruginosa antisera kit. The attachment of bacteria on contact lenses or human corneal epithelial cells was determined by counting the number of adhered bacteria after incubation of the bacteria with contact lenses or corneal epithelial cells. The 23 ocular isolates belonged to seven serotypes. Strains of serotypes I, G and E were the three dominant serogroups and were more adhesive to contact lenses compared with other groups of the bacteria. The bacterial serotypes and the clinical sequelae were not strongly related. These results indicate that the surface characteristics of bacterial serotypes are related to the bacterial adhesion to the surface, but the pathogenesis of the bacteria may result from multiple factors.
[1]
R. Schneider,et al.
An ocular strain of Pseudomonas aeruginosa is inflammatory but not virulent in the scarified mouse model.
,
1998,
Experimental eye research.
[2]
A. Husband,et al.
Different strains of Pseudomonas aeruginosa isolated from ocular infections or inflammation display distinct corneal pathologies in an animal model.
,
1998,
Current eye research.
[3]
T. Williams,et al.
Interactions of Bacteria with Contact Lenses: The Effect of Soluble Protein and Carbohydrate on Bacterial Adhesion to Contact Lenses
,
1998,
Optometry and vision science : official publication of the American Academy of Optometry.
[4]
A. Tsakris,et al.
On the incidence of antibiotic resistance among aerobic gram-negative rods isolated in Greek hospitals.
,
1993,
The Journal of hospital infection.