The Role of Polyamines in the Mechanisms of Cognitive Impairment

[1]  M. Marcoli,et al.  Transgenic Mouse Overexpressing Spermine Oxidase in Cerebrocortical Neurons: Astrocyte Dysfunction and Susceptibility to Epileptic Seizures , 2022, Biomolecules.

[2]  K. Soda.  Overview of Polyamines as Nutrients for Human Healthy Long Life and Effect of Increased Polyamine Intake on DNA Methylation , 2022, Cells.

[3]  S. Skatchkov,et al.  Critical Role of Astrocytic Polyamine and GABA Metabolism in Epileptogenesis , 2022, Frontiers in Cellular Neuroscience.

[4]  J. Steiner,et al.  Polyamines and polyamine-metabolizing enzymes in schizophrenia: Current knowledge and concepts of therapy , 2021, World journal of psychiatry.

[5]  J. Cleveland,et al.  Polyamine Homeostasis in Development and Disease , 2021, Medical sciences.

[6]  H. Tilg,et al.  Dietary spermidine improves cognitive function. , 2021, Cell reports.

[7]  A. Sickmann,et al.  eIF5A hypusination, boosted by dietary spermidine, protects from premature brain aging and mitochondrial dysfunction. , 2021, Cell reports.

[8]  S. Rajasekaran,et al.  Emerging Role of ODC1 in Neurodevelopmental Disorders and Brain Development , 2021, Genes.

[9]  B. Polis,et al.  Alzheimer’s disease as a chronic maladaptive polyamine stress response , 2021, Aging.

[10]  A. Wirth,et al.  Novel aspects of age-protection by spermidine supplementation are associated with preserved telomere length , 2021, GeroScience.

[11]  V. Baekelandt,et al.  ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress , 2020, Proceedings of the National Academy of Sciences.

[12]  Alexandra Kremer,et al.  The positive effect of spermidine in older adults suffering from dementia , 2020, Wiener klinische Wochenschrift.

[13]  D. Bredt,et al.  Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology , 2020, Nature Communications.

[14]  Qi Wang,et al.  Epileptiform Neuronal Discharges Impair Astrocyte Syncytial Isopotentiality in Acute Hippocampal Slices , 2020, Brain sciences.

[15]  Alexandra Kremer,et al.  Spermidine in dementia , 2019, Wiener klinische Wochenschrift.

[16]  C. F. Mello,et al.  Spermidine, a positive modulator of the NMDA receptor, facilitates extinction and prevents the reinstatement of morphine-induced conditioned place preference in mice , 2019, Psychopharmacology.

[17]  S. Aoki,et al.  A metabolic profile of polyamines in parkinson disease: A promising biomarker , 2019, Annals of neurology.

[18]  E. Weeber,et al.  Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response , 2019, Alzheimer's Research & Therapy.

[19]  Miranka Wirth,et al.  Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)—study protocol for a randomized controlled trial , 2019, Alzheimer's Research & Therapy.

[20]  S. Illarioshkin,et al.  Polyamines in Parkinson’s Disease: Their Role in Oxidative Stress Induction and Protein Aggregation , 2019, Journal of Neurology Research.

[21]  F. Tinahones,et al.  Dietary and Gut Microbiota Polyamines in Obesity- and Age-Related Diseases , 2019, Front. Nutr..

[22]  Miranka Wirth,et al.  The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial , 2018, Cortex.

[23]  Puneet Kumar,et al.  Neuroprotective potential of spermidine against rotenone induced Parkinson's disease in rats , 2018, Neurochemistry International.

[24]  A. Mattoo,et al.  Polyamines: Bio-Molecules with Diverse Functions in Plant and Human Health and Disease , 2018, Front. Chem..

[25]  D. Jindal,et al.  Potential effect of spermidine on GABA, dopamine, acetylcholinesterase, oxidative stress and proinflammatory cytokines to diminish ketamine-induced psychotic symptoms in rats. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[26]  G. Sukhikh,et al.  THE ROLE OF POLYAMINES IN FUNCTIONING OF REPRODUCTIVE SYSTEM CELLS , 2018 .

[27]  Xiaoling Chen,et al.  New insights into the role of spermine in enhancing the antioxidant capacity of rat spleen and liver under oxidative stress , 2016, Animal nutrition.

[28]  Stephan J Sigrist,et al.  Cardioprotection and lifespan extension by the natural polyamine spermidine , 2016, Nature Medicine.

[29]  C. F. Mello,et al.  Modulation of learning and memory by natural polyamines. , 2016, Pharmacological research.

[30]  M. Vawter,et al.  Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission , 2016, Neuroscience & Biobehavioral Reviews.

[31]  D. Pastré,et al.  Polyamine signal through gap junctions: A key regulator of proliferation and gap‐junction organization in mammalian tissues? , 2016, BioEssays : news and reviews in molecular, cellular and developmental biology.

[32]  K. Kashiwagi,et al.  Toxic acrolein production due to Ca(2+) influx by the NMDA receptor during stroke. , 2016, Atherosclerosis.

[33]  A. Aharoni,et al.  Circadian Clock Control by Polyamine Levels through a Mechanism that Declines with Age. , 2015, Cell metabolism.

[34]  Nektarios Tavernarakis,et al.  Spermidine protects against α-synuclein neurotoxicity , 2014, Cell cycle.

[35]  C. F. Mello,et al.  Spermidine improves fear memory persistence. , 2014, European journal of pharmacology.

[36]  L. Cynober,et al.  Aliphatic polyamines in physiology and diseases. , 2014, Clinical nutrition.

[37]  A. Pegg.  Toxicity of polyamines and their metabolic products. , 2013, Chemical research in toxicology.

[38]  Kazuei Igarashi,et al.  Polyamines and Their Metabolites as Diagnostic Markers of Human Diseases , 2013, Biomolecules & therapeutics.

[39]  K. Kashiwagi,et al.  Protein-conjugated acrolein as a biochemical marker of brain infarction. , 2011, Molecular nutrition & food research.

[40]  G. Turecki,et al.  Epigenetic regulation of spermidine/spermine N1-acetyltransferase (SAT1) in suicide. , 2011, Journal of psychiatric research.

[41]  Laetitia Mony,et al.  Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines , 2011, The EMBO journal.

[42]  F. Madeo,et al.  Polyamines in aging and disease , 2011, Aging.

[43]  A. Gratton,et al.  Evidence of Altered Polyamine Concentrations in Cerebral Cortex of Suicide Completers , 2010, Neuropsychopharmacology.

[44]  C. F. Mello,et al.  Spermine improves recognition memory deficit in a rodent model of Huntington’s disease , 2009, Neurobiology of Learning and Memory.

[45]  Frank Sinner,et al.  Induction of autophagy by spermidine promotes longevity , 2009, Nature Cell Biology.

[46]  P. Liu,et al.  Age-related changes in polyamines in memory-associated brain structures in rats , 2008, Neuroscience.

[47]  M. Sabater-Molina,et al.  Biological significance of dietary polyamines. , 2007, Nutrition.

[48]  J. Gemel,et al.  N-terminal residues in Cx43 and Cx40 determine physiological properties of gap junction channels, but do not influence heteromeric assembly with each other or with Cx26 , 2006, Journal of Cell Science.

[49]  K. Kashiwagi,et al.  Decrease in polyamines with aging and their ingestion from food and drink. , 2006, Journal of biochemistry.

[50]  C. Moinard,et al.  Polyamines: metabolism and implications in human diseases. , 2005, Clinical nutrition.

[51]  J. Gemel,et al.  Amino terminal glutamate residues confer spermine sensitivity and affect voltage gating and channel conductance of rat connexin40 gap junctions , 2004, The Journal of physiology.

[52]  A. Randi,et al.  Hexachlorobenzene-induced early changes in ornithine decarboxylase and protein tyrosine kinase activities, polyamines and c-Myc, c-Fos and c-Jun proto-oncogenes in rat liver. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.

[53]  K. Williams.  Interactions of polyamines with ion channels. , 1997, The Biochemical journal.

[54]  M. Mayer,et al.  Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel block , 1995, Neuron.

[55]  Anatoli N. Lopatin,et al.  Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification , 1994, Nature.

[56]  M. Mayer,et al.  Multiple effects of spermine on N‐methyl‐D‐aspartic acid receptor responses of rat cultured hippocampal neurones. , 1993, The Journal of physiology.

[57]  K. Williams,et al.  Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor , 1990, Neuron.

[58]  Joseph B. Martin.  Huntington's disease , 1984, Neurology.