Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection
暂无分享,去创建一个
A. Barzilai | P. Blinder | Tal Iram | Z. Fishelson | R. Vassar | D. Frenkel | David Kain | D. Trudler | R. Galron | S. Kanner | Sivan Kanner
[1] Nathan D. Kingery,et al. Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes , 2016, The Journal of Neuroscience.
[2] J. Rogers,et al. Analysis of the Putative Role of CR1 in Alzheimer’s Disease: Genetic Association, Expression and Function , 2016, PloS one.
[3] A. Verkhratsky,et al. Expression of familial Alzheimer disease presenilin 1 gene attenuates vesicle traffic and reduces peptide secretion in cultured astrocytes devoid of pathologic tissue environment , 2016, Glia.
[4] E. Chang,et al. Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse , 2016, Neuron.
[5] D. Lauffenburger,et al. Identification of neurotoxic cytokines by profiling Alzheimer’s disease tissues and neuron culture viability screening , 2015, Scientific Reports.
[6] A. Verkhratsky,et al. Glial Asthenia and Functional Paralysis , 2015, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
[7] Min Jung Park,et al. Abstract T MP20: Histone Methylation Patterns in Astrocytes are Influenced by Age Following Ischemia , 2015, Stroke.
[8] E. Hol,et al. Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction , 2014, Neurobiology of Aging.
[9] A. Lavi,et al. DOC2B and Munc13-1 differentially regulate neuronal network activity. , 2014, Cerebral cortex.
[10] Qingli Xiao,et al. Enhancing Astrocytic Lysosome Biogenesis Facilitates Aβ Clearance and Attenuates Amyloid Plaque Pathogenesis , 2014, The Journal of Neuroscience.
[11] Emily K. Lehrman,et al. An engulfment assay: a protocol to assess interactions between CNS phagocytes and neurons. , 2014, Journal of visualized experiments : JoVE.
[12] G. Ingram,et al. Complement activation in multiple sclerosis plaques: an immunohistochemical analysis , 2014, Acta Neuropathologica Communications.
[13] S. Mandel,et al. DJ‐1 deficiency triggers microglia sensitivity to dopamine toward a pro‐inflammatory phenotype that is attenuated by rasagiline , 2014, Journal of neurochemistry.
[14] E. Hol,et al. Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice , 2014, Neurobiology of Aging.
[15] E. Huang,et al. A Dramatic Increase of C1q Protein in the CNS during Normal Aging , 2013, The Journal of Neuroscience.
[16] Nathan D. Kingery,et al. Scara1 deficiency impairs clearance of soluble Amyloid-β by mononuclear phagocytes and accelerates Alzheimer’s-like disease progression , 2013, Nature Communications.
[17] D. Frenkel,et al. Scavenger Receptor A Deficiency Accelerates Cerebrovascular Amyloidosis in an Animal Model , 2013, Journal of Molecular Neuroscience.
[18] Andrew W. Kraft,et al. Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[19] E. Syková,et al. Astrocytic cytoskeletal atrophy in the medial prefrontal cortex of a triple transgenic mouse model of Alzheimer’s disease , 2012, Journal of anatomy.
[20] Peyman Golshani,et al. Associative Fear Learning Enhances Sparse Network Coding in Primary Sensory Cortex , 2012, Neuron.
[21] Ben A. Barres,et al. Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner , 2012, Neuron.
[22] B. Barres,et al. Genomic Analysis of Reactive Astrogliosis , 2012, The Journal of Neuroscience.
[23] F. Helmchen,et al. In vivo labeling of cortical astrocytes with sulforhodamine 101 (SR101). , 2012, Cold Spring Harbor protocols.
[24] M. Blankenstein,et al. The effect of amyloid associated proteins on the expression of genes involved in amyloid-β clearance by adult human astrocytes , 2012, Experimental Neurology.
[25] Mark H. Ellisman,et al. Development of a Method for the Purification and Culture of Rodent Astrocytes , 2011, Neuron.
[26] D. Peterson,et al. Phenotypic and gene expression modification with normal brain aging in GFAP‐positive astrocytes and neural stem cells , 2011, Aging cell.
[27] J. Rothstein,et al. Molecular comparison of GLT1+ and ALDH1L1+ astrocytes in vivo in astroglial reporter mice , 2011, Glia.
[28] D. Farfara,et al. γ‐Secretase component presenilin is important for microglia β‐amyloid clearance , 2011, Annals of neurology.
[29] J. Morris,et al. Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease , 2010, Science.
[30] D. Attwell,et al. Glial and neuronal control of brain blood flow , 2022 .
[31] R. Veerhuis,et al. Astrocytic Aβ1‐42 uptake is determined by Aβ‐aggregation state and the presence of amyloid‐associated proteins , 2010, Glia.
[32] A. Verkhratsky,et al. Early astrocytic atrophy in the entorhinal cortex of a triple transgenic animal model of Alzheimer's disease , 2011, ASN neuro.
[33] A. Verkhratsky,et al. Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease , 2010, Glia.
[34] A. Tenner,et al. C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production , 2010, Journal of neurochemistry.
[35] M. Sofroniew,et al. Astrocytes: biology and pathology , 2009, Acta Neuropathologica.
[36] M. Sofroniew. Molecular dissection of reactive astrogliosis and glial scar formation , 2009, Trends in Neurosciences.
[37] F. Heppner,et al. Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia , 2009, Nature Neuroscience.
[38] R. Veerhuis,et al. Binding and uptake of Aβ1‐42 by primary human astrocytes in vitro , 2009, Glia.
[39] G. Halliday,et al. Monocyte Chemoattractant Protein‐1 Plays a Dominant Role in the Chronic Inflammation Observed in Alzheimer's Disease , 2009, Brain pathology.
[40] Y. Xing,et al. A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function , 2008, The Journal of Neuroscience.
[41] K. Ravichandran,et al. Engulfment of apoptotic cells: signals for a good meal , 2007, Nature Reviews Immunology.
[42] P. Magistretti,et al. Activity‐dependent regulation of energy metabolism by astrocytes: An update , 2007, Glia.
[43] J. Rothstein,et al. Variations in Promoter Activity Reveal a Differential Expression and Physiology of Glutamate Transporters by Glia in the Developing and Mature CNS , 2007, The Journal of Neuroscience.
[44] F. L. D. Silva,et al. Complement activation in experimental and human temporal lobe epilepsy , 2007, Neurobiology of Disease.
[45] J. Rothstein,et al. Mechanisms of Disease: astrocytes in neurodegenerative disease , 2006, Nature Clinical Practice Neurology.
[46] M. Ohno,et al. Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation , 2006, The Journal of Neuroscience.
[47] David M Holtzman,et al. Human amyloid-β synthesis and clearance rates as measured in cerebrospinal fluid in vivo , 2006, Nature Medicine.
[48] R. Malenka,et al. Synaptic scaling mediated by glial TNF-α , 2006, Nature.
[49] Soojin Lee,et al. TLR3‐mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: Differential signaling mechanisms of TLR3‐induced IP‐10 and IL‐8 gene expression , 2006, Glia.
[50] R. von Bernhardi,et al. Expression of Scavenger Receptors in Glial Cells , 2005, Journal of Biological Chemistry.
[51] E. Newman,et al. Potassium buffering in the central nervous system , 2004, Neuroscience.
[52] F. Helmchen,et al. Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo , 2004, Nature Methods.
[53] Jun Zhou,et al. Absence of C1q Leads to Less Neuropathology in Transgenic Mouse Models of Alzheimer's Disease , 2004, The Journal of Neuroscience.
[54] T. Wyss-Coray,et al. Adult mouse astrocytes degrade amyloid-β in vitro and in situ , 2003, Nature Medicine.
[55] P. Mcgeer,et al. The possible role of complement activation in Alzheimer disease. , 2002, Trends in molecular medicine.
[56] J. Loike,et al. Scavenger receptors in neurobiology and neuropathology: Their role on microglia and other cells of the nervous system , 2002, Glia.
[57] B. Reed,et al. Very early‐onset familial Alzheimer's disease: a novel presenilin 1 mutation , 2002, International journal of geriatric psychiatry.
[58] M. Kanje,et al. Vascular endothelial growth factor is a neurotrophic factor which stimulates axonal outgrowth through the flk‐1 receptor , 2000, The European journal of neuroscience.
[59] K. Jin,et al. Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[60] K. Reid,et al. C1q: structure, function, and receptors. , 2000, Immunopharmacology.
[61] G. Lundborg,et al. Vascular Endothelial Growth Factor Has Neurotrophic Activity and Stimulates Axonal Outgrowth, Enhancing Cell Survival and Schwann Cell Proliferation in the Peripheral Nervous System , 1999, The Journal of Neuroscience.
[62] Jae-Wook Oh,et al. Interleukin-6 (IL-6) Production by Astrocytes: Autocrine Regulation by IL-6 and the Soluble IL-6 Receptor , 1999, The Journal of Neuroscience.
[63] M. Hediger,et al. Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate , 1996, Neuron.
[64] C. Cotman,et al. beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain. , 1994, Journal of immunology.
[65] A. Messing,et al. GFAP promoter directs astrocyte-specific expression in transgenic mice , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[66] L. Mucke,et al. Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[67] S. Yamazaki,et al. Proposal of standardized methods and reference for assaying recombinant human tumor necrosis factor. , 1986, Japanese Journal of Medical Science & Biology.
[68] T. Frenkel. Targeting the Role of Astrocytes in the Progression of Alzheimers Disease , 2012 .
[69] David Kleinfeld,et al. MPScope 2.0: A Computer System for Two-Photon Laser Scanning Microscopy with Concurrent Plasma-Mediated Ablation and Electrophysiology , 2009 .
[70] J. Bauer,et al. Interleukin-6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients , 2004, Acta Neuropathologica.
[71] H. Braak,et al. Amyloid β-protein (Aβ)-containing astrocytes are located preferentially near N-terminal-truncated Aβ deposits in the human entorhinal cortex , 2000, Acta Neuropathologica.
[72] H. Braak,et al. Staging of Alzheimer-related cortical destruction. , 1997, International psychogeriatrics.
[73] G. Neufeld,et al. Vascular endothelial growth factor and its receptors. , 1994, Progress in growth factor research.
[74] P. Eikelenboom,et al. An immunohistochemical study on cerebral vascular and senile plaque amyloid in Alzheimer’s dementia , 1984, Virchows Archiv. B, Cell pathology including molecular pathology.