Diagnostic systems by model selection: a case study

Probabilistic systems for diagnosing blue babies are constructed by model selection methods applied to a database of cases. Their performance are compared with a system built primarily by use of expert knowledge. Results indicate that purely automatic methods do not quite perform at the level of expert based systems, but when expert knowledge is incorporated properly, the methods look very promising.

[1]  W. Patefield,et al.  An Efficient Method of Generating Random R × C Tables with Given Row and Column Totals , 1981 .

[2]  N. Wermuth,et al.  Graphical Models for Associations between Variables, some of which are Qualitative and some Quantitative , 1989 .

[3]  N. Wermuth Model Search among Multiplicative Models , 1976 .

[4]  Michel Mouchart,et al.  Discussion on "Conditional independence in statistitical theory" by A.P. Dawid , 1979 .

[5]  A. Dawid Conditional Independence in Statistical Theory , 1979 .

[6]  Steffen L. Lauritzen,et al.  Bayesian updating in causal probabilistic networks by local computations , 1990 .

[7]  N. Wermuth,et al.  On Substantive Research Hypotheses, Conditional Independence Graphs and Graphical Chain Models , 1990 .

[8]  B. Thiesson,et al.  BIFROST { Block recursive models Induced From Relevant knowledge, Observations, and Statistical Techniques , 1992 .

[9]  K Bull,et al.  Combining clinical judgement and statistical data in expert systems: Over-the-telephone management decisions for critical congenital heart disease in the first month of life , 1989, International journal of clinical monitoring and computing.

[10]  Jens Damgaard Andersen,et al.  STENO:an expert system for medical diagnosis based on graphical models and model search , 1991 .

[11]  A. H. Murphy,et al.  Probability Forecasting in Meteorology , 1984 .

[12]  H. Akaike A new look at the statistical model identification , 1974 .

[13]  Prakash P. Shenoy,et al.  Axioms for probability and belief-function proagation , 1990, UAI.

[14]  David J. Spiegelhalter,et al.  Bayesian analysis in expert systems , 1993 .

[15]  Kristian G. Olesen,et al.  HUGIN - A Shell for Building Bayesian Belief Universes for Expert Systems , 1989, IJCAI.

[16]  A. P. Dawid,et al.  Applications of a general propagation algorithm for probabilistic expert systems , 1992 .

[17]  David J. Spiegelhalter,et al.  Local computations with probabilities on graphical structures and their application to expert systems , 1990 .

[18]  D. Edwards,et al.  A fast procedure for model search in multidimensional contingency tables , 1985 .

[19]  A. Dawid The Well-Calibrated Bayesian , 1982 .

[20]  J. N. R. Jeffers,et al.  Graphical Models in Applied Multivariate Statistics. , 1990 .

[21]  D. Spiegelhalter,et al.  Evaluation of a diagnostic algorithm for heart disease in neonates. , 1991, BMJ.

[22]  M. Frydenberg The chain graph Markov property , 1990 .

[23]  A. H. Murphy,et al.  Reliability of Subjective Probability Forecasts of Precipitation and Temperature , 1977 .

[24]  S. Lauritzen,et al.  Mixed graphical association models; discussions and reply , 1989 .

[25]  S. Lauritzen The EM algorithm for graphical association models with missing data , 1995 .