Association of Rad51 polymorphism with DNA repair in BRCA1 mutation carriers and sporadic breast cancer risk

[1]  R. Eils,et al.  Polymorphisms in the BRCA1 and ABCB1 genes modulate menopausal hormone therapy associated breast cancer risk in postmenopausal women , 2010, Breast Cancer Research and Treatment.

[2]  S. Bojesen,et al.  Missense Polymorphisms in BRCA1 and BRCA2 and Risk of Breast and Ovarian Cancer , 2009, Cancer Epidemiology, Biomarkers & Prevention.

[3]  F. Couch,et al.  Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers. , 2009, Cancer research.

[4]  K. Kyriacou,et al.  DNA-repair genetic polymorphisms and risk of breast cancer in Cyprus , 2009, Breast Cancer Research and Treatment.

[5]  Jeanette C Papp,et al.  Associations between Single Nucleotide Polymorphisms in Double-Stranded DNA Repair Pathway Genes and Familial Breast Cancer , 2009, Clinical Cancer Research.

[6]  S. Tommasi,et al.  Molecular and in silico analysis of BRCA1 and BRCA2 variants. , 2008, Mutation research.

[7]  F. Couch,et al.  RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. , 2007, American journal of human genetics.

[8]  B. Orelli,et al.  RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors. , 2007, Cancer research.

[9]  P. Souček,et al.  Role of single nucleotide polymorphisms and haplotypes in BRCA1 in breast cancer: Czech case–control study , 2007, Breast Cancer Research and Treatment.

[10]  M. Spitz,et al.  Mutagen sensitivity: a genetic predisposition factor for cancer. , 2007, Cancer research.

[11]  Giovanni Parmigiani,et al.  Meta-analysis of BRCA1 and BRCA2 penetrance. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[12]  R. Scott,et al.  The RAD51 135 G>C Polymorphism Modifies Breast Cancer and Ovarian Cancer Risk in Polish BRCA1 Mutation Carriers , 2007, Cancer Epidemiology Biomarkers & Prevention.

[13]  R. Elston,et al.  Genetic characterization and fine mapping of susceptibility loci for sarcoidosis in African Americans on chromosome 5 , 2006, Human Genetics.

[14]  M. Spitz,et al.  Mutagen sensitivity has high heritability: evidence from a twin study. , 2006, Cancer research.

[15]  E. Egelman,et al.  The Rad51/RadA N-terminal domain activates nucleoprotein filament ATPase activity. , 2006, Structure.

[16]  R. Shamir,et al.  A specific RAD51 haplotype increases breast cancer risk in Jewish non-Ashkenazi high-risk women. , 2006, European journal of cancer.

[17]  Cynthia A. Tucker,et al.  γ-Radiation-Induced Chromosomal Mutagen Sensitivity Is Associated with Breast Cancer Risk in African-American Women: Caffeine Modulates the Outcome of Mutagen Sensitivity Assay , 2006, Cancer Epidemiology Biomarkers & Prevention.

[18]  J. Freudenheim,et al.  p53 Mutation Analysis in Breast Tumors by a DNA Microarray Method , 2006, Cancer Epidemiology Biomarkers & Prevention.

[19]  A. Paradiso,et al.  BRCA1 mutations and polymorphisms in a hospital-based consecutive series of breast cancer patients from Apulia, Italy. , 2005, Mutation research.

[20]  D. Altshuler,et al.  A haplotype-based case-control study of BRCA1 and sporadic breast cancer risk. , 2005, Cancer research.

[21]  J. Thacker.  The RAD51 gene family, genetic instability and cancer. , 2005, Cancer letters.

[22]  C. Richardson.  RAD51, genomic stability, and tumorigenesis. , 2005, Cancer letters.

[23]  M. Daly,et al.  Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..

[24]  P. Kraft,et al.  Haplotype analysis of common variants in the BRCA1 gene and risk of sporadic breast cancer , 2004, Breast Cancer Research.

[25]  S. Edge,et al.  Dietary intake of conjugated linoleic acids and risk of premenopausal and postmenopausal breast cancer, Western New York Exposures and Breast Cancer Study (WEB Study). , 2004, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[26]  R. Scully,et al.  Molecular Functions of BRCA1 in the DNA Damage Response , 2004, Cancer biology & therapy.

[27]  R. Eeles,et al.  A single-nucleotide polymorphism in the RAD51 gene modifies breast cancer risk in BRCA2 carriers, but not in BRCA1 carriers or noncarriers , 2004, British Journal of Cancer.

[28]  R. Eeles,et al.  Polyglutamine repeat length in the AIB1 gene modifies breast cancer susceptibility in BRCA1 carriers , 2004, International journal of cancer.

[29]  Toshihiro Tanaka.  The International HapMap Project , 2003, Nature.

[30]  J. Haber,et al.  Yeast Rad52 and Rad51 Recombination Proteins Define a Second Pathway of DNA Damage Assessment in Response to a Single Double-Strand Break , 2003, Molecular and Cellular Biology.

[31]  Peter Donnelly,et al.  A comparison of bayesian methods for haplotype reconstruction from population genotype data. , 2003, American journal of human genetics.

[32]  Anna Jakubowska,et al.  Breast cancer risk reduction associated with the RAD51 polymorphism among carriers of the BRCA1 5382insC mutation in Poland. , 2003, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[33]  Tom H. Pringle,et al.  The human genome browser at UCSC. , 2002, Genome research.

[34]  A. Thompson,et al.  Chromosomal radiosensitivity in G2-phase lymphocytes identifies breast cancer patients with distinctive tumour characteristics , 2001, British Journal of Cancer.

[35]  B. Modan,et al.  A single nucleotide polymorphism in the 5' untranslated region of RAD51 and risk of cancer among BRCA1/2 mutation carriers. , 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[36]  G. Iliakis,et al.  Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[37]  R. Eeles,et al.  CAG and GGC repeat polymorphisms in the androgen receptor gene and breast cancer susceptibility in BRCA1/2 carriers and non-carriers , 2001, British Journal of Cancer.

[38]  M. Jasin,et al.  Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation. , 2001, Cancer research.

[39]  P. Donnelly,et al.  A new statistical method for haplotype reconstruction from population data. , 2001, American journal of human genetics.

[40]  R. Parshad,et al.  Radiation-induced chromatid breaks and deficient DNA repair in cancer predisposition. , 2001, Critical reviews in oncology/hematology.

[41]  S C West,et al.  Role of BRCA2 in control of the RAD51 recombination and DNA repair protein. , 2001, Molecular cell.

[42]  S. Elledge,et al.  Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. , 2000, Genes & development.

[43]  M B Daly,et al.  Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat. , 1999, American journal of human genetics.

[44]  M. Nair,et al.  DNA repair proficiency: a potential marker for identification of high risk members in breast cancer families. , 1998, Cancer letters.

[45]  Akira Shinohara,et al.  Rad51‐deficient vertebrate cells accumulate chromosomal breaks prior to cell death , 1998, The EMBO journal.

[46]  R. Patel,et al.  DNA repair proficiency in breast cancer patients and their first‐degree relatives , 1997, International journal of cancer.

[47]  D. Clayton,et al.  Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population. , 1997, Human molecular genetics.

[48]  R. Parshad,et al.  Deficient DNA repair capacity, a predisposing factor in breast cancer. , 1996, British Journal of Cancer.

[49]  M. Skolnick,et al.  Comparison of BRCA1 polymorphisms, rare sequence variants and/or missense mutations in unaffected and breast/ovarian cancer populations. , 1996, Human molecular genetics.

[50]  R. Parshad,et al.  DNA repair proficiency: potential susceptiblity factor for breast cancer. , 1994, Journal of the National Cancer Institute.

[51]  R. Parshad,et al.  X‐ray‐induced chromatid damage in relation to dna repair and cancer incidence in family members , 1993, International journal of cancer.

[52]  W. Ewens,et al.  Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). , 1993, American journal of human genetics.

[53]  T. Waldmann,et al.  Enhanced chromatid damage in blood lymphocytes after G2 phase x irradiation, a marker of the ataxia-telangiectasia gene. , 1990, Journal of the National Cancer Institute.

[54]  R. Parshad,et al.  Chromatid damage after G2 phase x-irradiation of cells from cancer-prone individuals implicates deficiency in DNA repair. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[55]  A. Bøyum.  SEPARATION OF WHITE BLOOD CELLS. , 1964 .

[56]  A. Paradiso,et al.  BRCA1 expression and molecular alterations in familial breast cancer. , 2009, Histology and histopathology.

[57]  Giu-Cheng Hsu,et al.  Genetic variants of BLM interact with RAD51 to increase breast cancer susceptibility. , 2009, Carcinogenesis.

[58]  I. Chirivella González,et al.  CASP8 D302H polymorphism delays the age of onset of breast cancer in BRCA1 and BRCA2 carriers , 2009, Breast Cancer Research and Treatment.

[59]  H. Stürzbecher,et al.  Characterisation of the promoter region of the human DNA-repair gene Rad51. , 2005, European journal of gynaecological oncology.

[60]  Nathaniel Rothman,et al.  Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. , 2004, Journal of the National Cancer Institute.

[61]  J. Błasiak,et al.  Analysis of the G/C polymorphism in the 5'-untranslated region of the RAD51 gene in breast cancer. , 2003, Acta biochimica Polonica.

[62]  K. Broman,et al.  Genetic epidemiology , 1999, International Journal of Obesity.

[63]  S. Roberts,et al.  Chromosomal radiosensitivity in G2-phase lymphocytes as an indicator of cancer predisposition. , 1996, Radiation research.

[64]  R C Elston,et al.  The Elston-Stewart algorithm for continuous genotypes and environmental factors. , 1992, Human heredity.

[65]  R. Elston,et al.  Generalized modulus power transformations , 1988 .

[66]  R. Elston,et al.  Testing the association between polymorphic markers and quantitative traits in pedigrees , 1987, Genetic epidemiology.

[67]  G. Klaus.  Lymphocytes : a practical approach , 1987 .

[68]  A. BØyum.  Separation of White Blood Cells , 1964, Nature.