HORMONES AND CHOLESTEROL ESTER METABOLISM

A study was made of the effects of testosterone, estradiol, ACTH, insulin, epinephrine and l‐thyroxine on a microsomal preparation of female rat liver esterifying enzyme and cholesterol plus palmitic, oleic and linoleic acids. In the doses used, these hormones modified the rate of ester synthesis. Further experiments showed that low doses of androgen or estrogen had a stimulating effect whereas high doses had an inhibitory effect.

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