Life on an island: A simulated population to support student projects in statistics

It is important for students learning statistical reasoning to see data in context. One of the best ways of achieving this is to involve students in data production and so in the past ten years we have had first-year students undertake real experiments of their own choosing as part of our introductory statistics course. However in practice students are limited in what they can do. Many want to conduct experiments involving human subjects, requiring ethics approval, while even those not wanting to use humans may have general health and safety issues. Epidemiological studies have really not been possible at all. We present an open-ended virtual environment, the Island, to help overcome these limitations while still engaging students with study design and data collection. Students work with a population of virtual humans living on the Island and are able to conduct a wide variety of experiments with them as subjects. The Islanders also live in villages, have ancestors and die from a range of diseases, allowing students to study the epidemiology of the island as well. In this paper we will give an overview of this Island and its design, highlighting some of the features and the issues, and sharing our experiences of using the Island in teaching and learning.

[1]  C. L. Lim,et al.  Human thermoregulation and measurement of body temperature in exercise and clinical settings. , 2008, Annals of the Academy of Medicine, Singapore.

[2]  Paul Darius,et al.  SETTING UP EXPERIMENTS IN VETERINARY SCIENCE: AN EXAMPLE OF VIRTUAL EXPERIMENTATION , 2010 .

[3]  S. Welle,et al.  Normal thermic effect of glucose in obese women. , 1983, The American journal of clinical nutrition.

[4]  S. Ziebland,et al.  Effects of fruit and vegetable consumption on plasma antioxidant concentrations and blood pressure: a randomised controlled trial , 2002, The Lancet.

[5]  C. Wild Virtual Environments and the Acceleration of Experiential Learning , 2007 .

[6]  Michael Bulmer,et al.  Harnessing the creativity of science students to develop an online learning tool , 2011 .

[7]  K. Teo,et al.  Optimal insulin infusion resulting from a mathematical model of blood glucose dynamics , 1989, IEEE Transactions on Biomedical Engineering.

[8]  M. Altemus,et al.  Preliminary research on plasma oxytocin in normal cycling women: investigating emotion and interpersonal distress. , 1999, Psychiatry.

[9]  M. Meguid,et al.  Nicotine's effect on hypothalamic neurotransmitters and appetite regulation. , 1999, Surgery.

[10]  Bruce T. Smith,et al.  Plasma lipid and lipoprotein responses to dietary fat and cholesterol: a meta-analysis. , 1997, The American journal of clinical nutrition.

[11]  P. Tothill,et al.  The dependence of paracetamol absorption on the rate of gastric emptying , 1973, British journal of pharmacology.

[12]  C R Wyss,et al.  Control of skin blood flow, sweating, and heart rate: role of skin vs. core temperature. , 1974, Journal of applied physiology.

[13]  J. H. Comroe,et al.  The effect of the inhalation of high and low oxygen concentrations on respiration, pulse rate, ballistocardiogram and arterial oxygen saturation (oximeter) of normal individuals. , 1947, The American journal of physiology.

[14]  D. Costill,et al.  Fluid replacement during prolonged exercise: effects of water, saline, or no fluid. , 1991, Medicine and science in sports and exercise.

[15]  V. Candas,et al.  Alcohol and its variable effect on human thermoregulatory response to exercise in a warm environment , 2006, European Journal of Applied Physiology and Occupational Physiology.

[16]  B Kemp,et al.  Simulation of human hypnograms using a Markov chain model. , 1986, Sleep.

[17]  S. Shacham,et al.  A shortened version of the Profile of Mood States. , 1983, Journal of personality assessment.

[18]  Eddie Schrevens,et al.  Virtual Experiments and Their Use in Teaching Experimental Design , 2007 .

[19]  Ruth Crowther,et al.  Applying theory to practice in an undergraduate public health course , 2011 .

[20]  Helen MacGillivray,et al.  Student discovery projects in data analysis , 2010 .

[21]  B. MacIntosh,et al.  Caffeine ingestion and performance of a 1,500-metre swim. , 1995, Canadian journal of applied physiology = Revue canadienne de physiologie appliquee.

[22]  W. Kindermann,et al.  Changes in β-Endorphin Levels in Response to Aerobic and Anaerobic Exercise , 1992 .

[23]  K. Yoshida,et al.  Impact of body mass index on cholesterol levels of Japanese adults , 2006 .

[24]  Anthony Bedford,et al.  Teaching clinical trial design and management using an online virtual environment , 2011 .

[25]  J. Hill,et al.  Randomized evaluation of a low fat ad libitum carbohydrate diet for weight reduction. , 1993, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[26]  W. Kindermann,et al.  Changes in beta-endorphin levels in response to aerobic and anaerobic exercise. , 1992, Sports medicine.

[27]  E. Jéquier,et al.  Increased 24-hour energy expenditure in cigarette smokers. , 1986, The New England journal of medicine.

[28]  E. Ding,et al.  Nutrition & Metabolism BioMed Central Review Chocolate and Prevention of Cardiovascular Disease: A Systematic Review , 2005 .

[29]  C. Libersa,et al.  The effect of alcohol consumption on the circadian control of human core body temperature is time dependent. , 2001, American journal of physiology. Regulatory, integrative and comparative physiology.

[30]  Keith Wesnes,et al.  Oxygen administration selectively enhances cognitive performance in healthy young adults: a placebo-controlled double-blind crossover study , 1998, Psychopharmacology.

[31]  W. Kratzer,et al.  Factors Affecting Liver Size , 2003, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[32]  Mackisack Margaret What Is the Use of Experiments Conducted By Statistics Students , 1994 .

[33]  P. Joyce,et al.  Plasma oxytocin levels in depression and their correlation with the temperament dimension of reward dependence , 2006, Journal of psychopharmacology.

[34]  T. Hedner,et al.  Smoking affects blood pressure. , 1996, Blood pressure.

[35]  F. Dekker,et al.  Bias in clinical research. , 2008, Kidney international.

[36]  L C Gatewood,et al.  Mathematical analysis of blood glucose and plasma insulin responses to insulin infusion in healthy and diabetic subjects. , 1973, Computers in biology and medicine.

[37]  E. Coyle,et al.  Rehydration after Exercise with Common Beverages and Water , 1992, International journal of sports medicine.

[38]  W. Connor,et al.  The serum lipids in men receiving high cholesterol and cholesterol-free diets. , 1961, The Journal of clinical investigation.

[39]  C. Cook,et al.  Studies of respiratory physiology in children. I. Mechanics of respiration and lung volumes in 85 normal children 5 to 17 years of age. , 1958, Pediatrics.

[40]  A. Sonnenberg,et al.  Liver size evaluated by ultrasound: ROC curves for hepatitis and alcoholism. , 1984, Radiology.

[41]  E. Barrett-Connor,et al.  Alcohol Consumption and Blood Pressure , 2005 .

[42]  G. Peyman,et al.  Effects of morphine on corneal sensitivity and epithelial wound healing: implications for topical ophthalmic analgesia. , 1994, The British journal of ophthalmology.

[43]  W. Albrecht,et al.  Biological activity of synthetic human insulin , 1977, Diabetologia.

[44]  J. J. Higgins,et al.  Nonmathematical Statistics: A New Direction for the Undergraduate Discipline , 1999 .

[45]  M. Mitchell,et al.  Breast-feeding and plasma oxytocin concentrations. , 1980, British medical journal.

[46]  Michael Bulmer Collaborative Development of a Virtual Environment to Support Learning in Experimental Design and Statistical Analysis , 2011 .

[47]  H. L. Macgillivray Developing and synthesizing statistical skills for real situations through student projects , 1998 .

[48]  A. Grollman PHYSIOLOGICAL VARIATIONS OF THE CARDIAC OUTPUT IN MAN: X. The Effect of Variations in the Environmental Temperature on the Pulse Rate, Blood Pressure, Oxygen Comsumption, Arterio-Venous Oxygen Difference, and Cardiac Output of Normal Individuals , 1930 .

[49]  T. Ogaki,et al.  Thermoregulatory responses to low-intensity prolonged swimming in water at various temperatures and treadmill walking on land. , 2001, Journal of physiological anthropology and applied human science.

[50]  S. Bondurant,et al.  Effects of oxygen breathing on the heart rate, blood pressure, and cardiac index of normal men--resting, with reactive hyperemia, and after atropine. , 1962, The Journal of clinical investigation.

[51]  Joan Garfield,et al.  The Role of Technology in Improving Student Learning of Statistics , 2007 .

[52]  M. Huestis,et al.  Relating Blood Concentrations of Tetrahydrocannabinol and Metabolites to Pharmacologic Effects and Time of Marijuana Usage , 1993, Therapeutic drug monitoring.

[53]  P. Lewis Australian guidelines to reduce health risks from drinking alcohol , 2009 .

[54]  R. Edelberg,et al.  Psychopathology and psychophysiology of minimal LSD-25 dosage; a preliminary dosage-response spectrum. , 1958, A.M.A. archives of neurology and psychiatry.

[55]  S. Franceschi,et al.  Glycemic index: overview of implications in health and disease. , 2002, The American journal of clinical nutrition.

[56]  S. Bird,et al.  Effect of caffeinated coffee on running speed, respiratory factors, blood lactate and perceived exertion during 1500-m treadmill running. , 1992, British journal of sports medicine.

[57]  P. Easterbrook,et al.  Publication bias in clinical research , 1991, The Lancet.

[58]  S. Necozione,et al.  Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons. , 2005, The American journal of clinical nutrition.

[59]  M. Burr,et al.  Peak expiratory flow rates before and after exercise in schoolchildren , 1974, Archives of disease in childhood.

[60]  C. Heather Ashton,et al.  Pharmacology and effects of cannabis: A brief review , 2001, British Journal of Psychiatry.

[61]  D. M. Keenan,et al.  Effects of continuous versus intermittent exercise, obesity, and gender on growth hormone secretion. , 2008, The Journal of clinical endocrinology and metabolism.

[62]  J. Davidson,et al.  Relationships among cardiovascular, muscular, and oxytocin responses during human sexual activity , 1994, Archives of sexual behavior.