Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality.
暂无分享,去创建一个
M. Pellegrini | M. Morselli | S. Fitz-Gibbon | D. Walker | R. Yamada | W. Ja | Michael Rera | A. Rana | David W. Walker | Rebecca I. Clark | J. Alcaraz | Anna M Salazar
[1] R. Yamada,et al. Microbes Promote Amino Acid Harvest to Rescue Undernutrition in Drosophila. , 2015, Cell reports.
[2] Bernard M. Corfe,et al. Dysbiosis of the gut microbiota in disease , 2015, Microbial ecology in health and disease.
[3] F. Bäckhed,et al. Microbial modulation of insulin sensitivity. , 2014, Cell metabolism.
[4] M. Wayland,et al. Spotting the differences: Probing host/microbiota interactions with a dedicated software tool for the analysis of faecal outputs in Drosophila , 2014, Journal of insect physiology.
[5] Edan Foley,et al. A Deregulated Intestinal Cell Cycle Program Disrupts Tissue Homeostasis without Affecting Longevity in Drosophila* , 2014, The Journal of Biological Chemistry.
[6] Nichole A. Broderick,et al. Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology , 2014, mBio.
[7] William B. Mair,et al. You Are What You Host: Microbiome Modulation of the Aging Process , 2014, Cell.
[8] H. Jasper,et al. PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan , 2014, Cell.
[9] S. Gianella,et al. An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia , 2014, Mucosal Immunology.
[10] H. Jasper,et al. Promoting longevity by maintaining metabolic and proliferative homeostasis , 2014, Journal of Experimental Biology.
[11] Jessamina E. Blum,et al. Frequent Replenishment Sustains the Beneficial Microbiome of Drosophila melanogaster , 2013, mBio.
[12] Sepehr Bahadorani,et al. Increased longevity mediated by yeast NDI1 expression in Drosophila intestinal stem and progenitor cells , 2013, Aging.
[13] D. Walker,et al. Organ-specific mediation of lifespan extension: More than a gut feeling? , 2013, Ageing Research Reviews.
[14] F. Leulier,et al. Host-intestinal microbiota mutualism: "learning on the fly". , 2013, Cell host & microbe.
[15] D. Walker,et al. Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila , 2012, Proceedings of the National Academy of Sciences.
[16] E. Deitch. Gut-origin sepsis: evolution of a concept. , 2012, The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland.
[17] J. Clemente,et al. Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice. , 2012, Cell host & microbe.
[18] D. Sinderen,et al. Gut microbiota composition correlates with diet and health in the elderly , 2012, Nature.
[19] J. Nicholson,et al. Host-Gut Microbiota Metabolic Interactions , 2012, Science.
[20] Fiona Powrie,et al. Microbiota, Disease, and Back to Health: A Metastable Journey , 2012, Science Translational Medicine.
[21] B. Lemaître,et al. Gut-associated microbes of Drosophila melanogaster , 2012, Gut microbes.
[22] J. Clemente,et al. The Impact of the Gut Microbiota on Human Health: An Integrative View , 2012, Cell.
[23] H. Raybould. Gut microbiota, epithelial function and derangements in obesity , 2012, The Journal of physiology.
[24] Sepehr Bahadorani,et al. Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. , 2011, Cell metabolism.
[25] Yongan Zhao,et al. RAPSearch2: a fast and memory-efficient protein similarity search tool for next-generation sequencing data , 2011, Bioinform..
[26] P. Sansonetti,et al. Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment , 2011, EMBO molecular medicine.
[27] S. Schuster,et al. Integrative analysis of environmental sequences using MEGAN4. , 2011, Genome research.
[28] Patrick Ng,et al. Low-diversity bacterial community in the gut of the fruitfly Drosophila melanogaster. , 2011, Environmental microbiology.
[29] A. Bailey,et al. Enteric Neurons and Systemic Signals Couple Nutritional and Reproductive Status with Intestinal Homeostasis , 2011, Cell metabolism.
[30] R. Lehmann,et al. Lifespan Extension by Preserving Proliferative Homeostasis in Drosophila , 2010, PLoS genetics.
[31] S. Pittaluga,et al. Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections , 2010, PLoS pathogens.
[32] Marcus J. Claesson,et al. Composition, variability, and temporal stability of the intestinal microbiota of the elderly , 2010, Proceedings of the National Academy of Sciences.
[33] P. Brigidi,et al. Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians , 2010, PloS one.
[34] A. Marchiando,et al. Epithelial barriers in homeostasis and disease. , 2010, Annual review of pathology.
[35] Alyssa Bost,et al. A Transient Niche Regulates the Specification of Drosophila Intestinal Stem Cells , 2010, Science.
[36] Jerrold R. Turner,et al. Intestinal mucosal barrier function in health and disease , 2009, Nature Reviews Immunology.
[37] B. Lemaître,et al. Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila. , 2009, Genes & development.
[38] L. Partridge,et al. The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila , 2009, Proceedings of the Royal Society B: Biological Sciences.
[39] Joung-Sun Park,et al. The role of p38b MAPK in age-related modulation of intestinal stem cell proliferation and differentiation in Drosophila , 2009, Aging.
[40] B. Biteau,et al. JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut. , 2008, Cell stem cell.
[41] Laurent Seroude,et al. Characterization of the Drosophila Gene‐Switch system in aging studies: a cautionary tale , 2008, Aging cell.
[42] Mi-Ae Yoo,et al. Age-related changes in Drosophila midgut are associated with PVF2, a PDGF/VEGF-like growth factor , 2008, Aging cell.
[43] J. Ryu,et al. Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in Drosophila , 2008, Science.
[44] I. Alexandrov,et al. Removing endosymbiotic Wolbachia specifically decreases lifespan of females and competitiveness in a laboratory strain of Drosophila melanogaster , 2007, Russian Journal of Genetics.
[45] J. Tower,et al. Increased internal and external bacterial load during Drosophila aging without life-span trade-off. , 2007, Cell metabolism.
[46] S. Benzer,et al. Prandiology of Drosophila and the CAFE assay , 2007, Proceedings of the National Academy of Sciences.
[47] H. Harmsen,et al. Fecal Microbiota Composition and Frailty , 2005, Applied and Environmental Microbiology.
[48] Claudio Franceschi,et al. What accounts for the wide variation in life span of genetically identical organisms reared in a constant environment? , 2005, Mechanisms of Ageing and Development.
[49] S. Benzer,et al. Drosophila lifespan enhancement by exogenous bacteria. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[50] S. Benzer,et al. Wolbachia, normally a symbiont of Drosophila, can be virulent, causing degeneration and early death. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[51] Jerry Cheng,et al. Contribution of the Intestinal Microbiota to Human Health: From Birth to 100 Years of Age (online first) , 2012 .
[52] Haixu Tang,et al. RAPSearch 2 : a fast and memory-efficient protein similarity search tool for next-generation sequencing data , 2011 .
[53] Alexander F. Auch,et al. MEGAN analysis of metagenomic data , 2007 .