Inhibition of RNA polymerase II as a trigger for the p53 response
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[1] B. McKay,et al. Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis , 1998, Oncogene.
[2] A. Levine,et al. Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[3] D. Brash,et al. Antioxidant action via p53-mediated apoptosis. , 1998, Cancer research.
[4] T. Hunter,et al. Expression of a novel form of p21Cip1/Waf1 in UV-irradiated and transformed cells , 1998, Oncogene.
[5] James M. Roberts,et al. Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade. , 1998, Molecular cell.
[6] A. Takahashi,et al. p53-dependent induction of WAF1 by cold shock in human glioblastoma cells , 1998, Oncogene.
[7] W. P. McLaughlin,et al. Butyrate attenuates BCLX(L) expression in human fibroblasts and acts in synergy with ionizing radiation to induce apoptosis. , 1998, Radiation research.
[8] K. Yano,et al. DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. , 1998, Genes & development.
[9] M L Agarwal,et al. The p53 Network* , 1998, The Journal of Biological Chemistry.
[10] A. Giaccia,et al. Transformed cells require continuous activity of RNA polymerase II to resist oncogene-induced apoptosis , 1997, Molecular and cellular biology.
[11] E. Appella,et al. Prolonged p53 protein accumulation in trichothiodystrophy fibroblasts dependent on unrepaired pyrimidine dimers on the transcribed strands of cellular genes , 1997, Molecular carcinogenesis.
[12] B. Wasylyk,et al. Transcription Abnormalities Potentiate Apoptosis of Normal Human Fibroblasts , 1997, Molecular medicine.
[13] B. Gilchrest,et al. Enhancement of DNA repair in human skin cells by thymidine dinucleotides: evidence for a p53-mediated mammalian SOS response. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[14] W. Jongmans,et al. Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation , 1997, Molecular and cellular biology.
[15] Raouf Fetni,et al. A p53-independent pathway for induction of p21waf1cip1 and concomitant G1 arrest in UV-irradiated human skin fibroblasts. , 1997, Cancer research.
[16] L. Bracco,et al. Proteolysis by calpains: a possible contribution to degradation of p53 , 1997, Molecular and cellular biology.
[17] A. Ciechanover,et al. On the involvement of calpains in the degradation of the tumor suppressor protein p53 , 1997, FEBS letters.
[18] A. Levine. p53, the Cellular Gatekeeper for Growth and Division , 1997, Cell.
[19] H. Drexler. Activation of the cell death program by inhibition of proteasome function. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[20] B. McKay,et al. Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene. , 1997, Carcinogenesis.
[21] J. Roth,et al. Induction of apoptosis in human lung cancer cells after wild-type p53 activation by methoxyestradiol , 1997, Oncogene.
[22] M. Kubbutat,et al. Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability , 1997, Molecular and cellular biology.
[23] P. Howley,et al. Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation , 1997, Molecular and cellular biology.
[24] A. Jochemsen,et al. How phosphorylation regulates the activity of p53. , 1996, Journal of molecular biology.
[25] P. O'Connor,et al. Abrogation of p53 function affects gadd gene responses to DNA base-damaging agents and starvation. , 1996, DNA and cell biology.
[26] M. Vigneron,et al. In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitin. , 1996, Nucleic acids research.
[27] M. Kastan. Signalling to p53: where does it all start? , 1996, BioEssays : news and reviews in molecular, cellular and developmental biology.
[28] M. Minden,et al. Translational regulation of human p53 gene expression. , 1996, The EMBO journal.
[29] K. Shinohara,et al. Apoptosis induction resulting from proteasome inhibition. , 1996, The Biochemical journal.
[30] M. Ljungman. Effect of differential gene expression on the chromatin structure of the DHFR gene domain in vivo. , 1996, Biochimica et biophysica acta.
[31] C. Harris,et al. p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective. , 1996, Carcinogenesis.
[32] P. Howley,et al. In vivo ubiquitination and proteasome-mediated degradation of p53(1). , 1996, Cancer research.
[33] C. Prives,et al. p53: puzzle and paradigm. , 1996, Genes & development.
[34] G. Wahl,et al. A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. , 1996, Genes & development.
[35] R. Tishler,et al. Microtubule-active drugs taxol, vinblastine, and nocodazole increase the levels of transcriptionally active p53. , 1995, Cancer research.
[36] S. Lippard,et al. DNA adducts of cis-diamminedichloroplatinum(II) and its trans isomer inhibit RNA polymerase II differentially in vivo. , 1995, Biochemistry.
[37] D. Lane,et al. Small peptides activate the latent sequence-specific DNA binding function of p53 , 1995, Cell.
[38] L. Neckers,et al. Taxol induction of p21WAF1 and p53 requires c-raf-1. , 1995, Cancer research.
[39] D. Bentley,et al. The Transcriptional Elongation Inhibitor 5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole Inhibits Transcription Factor IIH-associated Protein Kinase (*) , 1995, The Journal of Biological Chemistry.
[40] P. Hanawalt,et al. Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[41] D. Lane,et al. Tumour suppressors, kinases and clamps: How p53 regulates the cell cycle in response to DNA damage , 1995, BioEssays : news and reviews in molecular, cellular and developmental biology.
[42] P. Hanawalt,et al. Presence of negative torsional tension in the promoter region of the transcriptionally poised dihydrofolate reductase gene in vivo. , 1995, Nucleic acids research.
[43] K. Kinzler,et al. p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. , 1995, Genes & development.
[44] K. Okaichi,et al. p53 proteins accumulated by heat stress associate with heat shock proteins HSP72/HSC73 in human glioblastoma cell lines. , 1994, Cancer letters.
[45] A. Fornace,et al. The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia. , 1994, Cancer research.
[46] T. Graeber,et al. Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status , 1994, Molecular and cellular biology.
[47] P. Hanawalt,et al. Transcript cleavage by RNA polymerase II arrested by a cyclobutane pyrimidine dimer in the DNA template. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[48] S. Grant,et al. Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C. , 1994, Cancer research.
[49] D. Chowdary,et al. Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway , 1994, Molecular and cellular biology.
[50] M. Kastan,et al. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways , 1994, Molecular and cellular biology.
[51] L. Liu,et al. DNA topoisomerases: essential enzymes and lethal targets. , 1994, Annual review of pharmacology and toxicology.
[52] L. Ferguson,et al. Topoisomerase II enzymes and mutagenicity , 1994, Environmental and molecular mutagenesis.
[53] Xin Lu,et al. Differential induction of transcriptionally active p53 following UV or lonizing radiation: Defects in chromosome instability syndromes? , 1993, Cell.
[54] C. Job,et al. Spectrum of DNA--platinum adduct recognition by prokaryotic and eukaryotic DNA-dependent RNA polymerases. , 1993, Biochemistry.
[55] A. Fornace,et al. Induction of Cellular p53 Activity by DNA-Damaging Agents and Growth Arrest , 1993, Molecular and cellular biology.
[56] C. N. Coleman,et al. Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents. , 1993, Cancer research.
[57] C. Purdie,et al. Thymocyte apoptosis induced by p53-dependent and independent pathways , 1993, Nature.
[58] Scott W. Lowe,et al. p53 is required for radiation-induced apoptosis in mouse thymocytes , 1993, Nature.
[59] D. Lane,et al. Regulation of the specific DNA binding function of p53 , 1992, Cell.
[60] B. Vogelstein,et al. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia , 1992, Cell.
[61] P. Friedman,et al. Wild-type p53 activates transcription in vitro , 1992, Nature.
[62] A. Levine,et al. Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element. , 1992, Genes & development.
[63] B. Vogelstein,et al. Participation of p53 protein in the cellular response to DNA damage. , 1991, Cancer research.
[64] M. Yaniv,et al. Wild-type p53 can down-modulate the activity of various promoters. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[65] Arnold J. Levine,et al. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53 , 1990, Cell.
[66] W. Sauerbier,et al. Structure of transcriptionally active chromatin: Radiological evidence for requirement of torsionally constrained DNA , 1989, Journal of cellular physiology.
[67] G. Georgiev,et al. Inhibition of transcription in eukaryotic cells by X-irradiation: relation to the loss of topological constraint in closed DNA loops. , 1988, Nucleic acids research.
[68] J. Ward,et al. DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. , 1988, Progress in nucleic acid research and molecular biology.
[69] A. Eastman. Reevaluation of interaction of cis-dichloro(ethylenediamine)platinum(II) with DNA. , 1986, Biochemistry.
[70] H. M. Sobell. Actinomycin and DNA transcription. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[71] S. Kawamoto,et al. Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. , 1984, Biochemistry.
[72] W. Maltzman,et al. UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells , 1984, Molecular and cellular biology.
[73] K. Erixon,et al. Single-strand breaks in DNA during repair of UV-induced damage in normal human and xeroderma pigmentosum cells as determined by alkaline DNA unwinding and hydroxylapatite chromatography: effects of hydroxyurea, 5-fluorodeoxyuridine and 1-beta-D-arabinofuranosylcytosine on the kinetics of repair. , 1979, Mutation research.
[74] W. Sauerbier,et al. Gene and transcription unit mapping by radiation effects. , 1978, Annual review of genetics.
[75] J. Darnell,et al. The inhibition of DRB (5,6-dichloro-1-β-d-ribofuranosylbenzimidazole) of hnRNA and mRNA production in HeLa cells , 1976, Cell.
[76] E. Egyházi. Initiation inhibition and reinitiation of the synthesis of heterogeneous nuclear RNA in living cells , 1976, Nature.
[77] M. Kuwano,et al. Inhibition by alpha-amanitin of messenger RNA formation in cultured fibroblasts: potentiation by amphotericin B. , 1973, Experimental cell research.
[78] R. Perry,et al. Inhibition of RNA synthesis by actinomycin D: Characteristic dose‐response of different RNA species , 1970, Journal of cellular physiology.