Classification of variations of HSA21 gene expression in down syndrome lymphoblastoid cell lines : impact on disease phenotype

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Classification of variations of HSA21 gene expression in down syndrome lymphoblastoid cell lines : impact on disease phenotype E. Aït Yahya-Graison, Julie Aubert, L. Dauphinot, Isabelle Rivals, Marguerite Prieur, G. Golfier, J. Rossier, L. Personnaz, N Créau, Stephane Robin, et al.

[1]  O. Christophe,et al.  Paraoxonase-1 expression is up-regulated in Down syndrome fetal liver. , 2006, Biochemical and biophysical research communications.

[2]  Tom C. Freeman,et al.  An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes , 2006, Nucleic acids research.

[3]  L. Personnaz,et al.  Transcriptional disruptions in Down syndrome: a case study in the Ts1Cje mouse cerebellum during post‐natal development , 2006, Journal of neurochemistry.

[4]  Anna Tramontano,et al.  Identification of a novel putative mitogen-activated kinase cascade on human chromosome 21 by computational approaches , 2006, Bioinform..

[5]  B. Tycko,et al.  Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21 , 2006, BMC Medical Genetics.

[6]  Ingo Ruczinski,et al.  Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart , 2005, Genome Biology.

[7]  C. V. Jongeneel,et al.  Gene expression variation and expression quantitative trait mapping of human chromosome 21 genes. , 2005, Human molecular genetics.

[8]  H. Yoo,et al.  Gene Expression Analysis of Cultured Amniotic Fluid Cell with Down Syndrome by DNA Microarray , 2005, Journal of Korean medical science.

[9]  L. Personnaz,et al.  The cerebellar transcriptome during postnatal development of the Ts1Cje mouse, a segmental trisomy model for Down syndrome. , 2005, Human molecular genetics.

[10]  A. Hershey,et al.  Blood expression profiles for tuberous sclerosis complex 2, neurofibromatosis type 1, and down's syndrome , 2004, Annals of neurology.

[11]  L. Vitale,et al.  Gene Expression Profile Analysis in Human T Lymphocytes from Patients with Down Syndrome , 2004, Annals of human genetics.

[12]  Stylianos E. Antonarakis,et al.  Chromosome 21 and Down syndrome: from genomics to pathophysiology , 2004, Nature Reviews Genetics.

[13]  Jean-Jacques Daudin,et al.  Determination of the differentially expressed genes in microarray experiments using local FDR , 2004, BMC Bioinformatics.

[14]  S. Antonarakis,et al.  Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome. , 2004, Genome research.

[15]  K. Yamakawa,et al.  Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome. , 2004, Human molecular genetics.

[16]  S. South,et al.  Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome. , 2004, Genome research.

[17]  Katheleen Gardiner,et al.  Mouse models of Down syndrome: how useful can they be? Comparison of the gene content of human chromosome 21 with orthologous mouse genomic regions. , 2003, Gene.

[18]  R. Reeves,et al.  Global disruption of the cerebellar transcriptome in a Down syndrome mouse model. , 2003, Human molecular genetics.

[19]  Jonathan Pevsner,et al.  Global up-regulation of chromosome 21 gene expression in the developing Down syndrome brain. , 2003, Genomics.

[20]  N. Hastie,et al.  Transcriptome analysis of human autosomal trisomy. , 2002, Human molecular genetics.

[21]  B. Morrow,et al.  Gene expression profile of trisomy 21 placentas: a potential approach for designing noninvasive techniques of prenatal diagnosis. , 2002, American journal of obstetrics and gynecology.

[22]  C. V. Jongeneel,et al.  Nineteen additional unpredicted transcripts from human chromosome 21. , 2002, Genomics.

[23]  S. P. Fodor,et al.  Large-Scale Transcriptional Activity in Chromosomes 21 and 22 , 2002, Science.

[24]  B. L. Shapiro.  Developmental instability of the cerebellum and its relevance to Down syndrome. , 2001, Journal of neural transmission. Supplementum.

[25]  Pierre R. Bushel,et al.  Assessing Gene Significance from cDNA Microarray Expression Data via Mixed Models , 2001, J. Comput. Biol..

[26]  Y Sakaki,et al.  The DNA sequence of human chromosome 21. , 2000, Nature.

[27]  S. Antonarakis,et al.  Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome. , 1998, Genomics.

[28]  S. Antonarakis,et al.  Cloning of 559 potential exons of genes of human chromosome 21 by exon trapping. , 1996, Genome research.

[29]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .

[30]  J. Delabar,et al.  Molecular Mapping of Twenty-Four Features of Down Syndrome on Chromosome 21 , 1993, European journal of human genetics : EJHG.

[31]  E. Courchesne,et al.  Protocols to establish genotype-phenotype correlations in Down syndrome. , 1991, American journal of human genetics.

[32]  D. Levanon,et al.  Human Cu/Zn superoxide dismutase gene: molecular characterization of its two mRNA species. , 1984, Nucleic acids research.