Feasibility of Biomedical Applications of Hall Effect Imaging

Hall effect imaging is a new technique for mapping the electrical properties of a sample. Its principle has been demonstrated in two- and three-dimensional phantom images. Based on the experimental data and theoretical understanding of this technique developed over the past few years, this paper addresses the most relevant question for biomedical applications: whether Hall effect imaging is ultimately applicable to complex biological systems such as the human body. The arguments are given at the basic physics level, so that the conclusion is independent of current technology status. These arguments are corroborated with imaging data of an aorta sample. The conclusion is that Hall effect imaging is not suited for quantifying the electrical constants in complex biological samples. This technique is able to produce high-resolution volume images of samples in vitro that reflect their electrical heterogeneity. However, quantitative measurements of electrical constants are not practical for complex samples.

[1]  J P Morucci,et al.  Bioelectrical impedance techniques in medicine. Part III: Impedance imaging. Third section: medical applications. , 1996, Critical reviews in biomedical engineering.

[2]  K. Foster,et al.  Dielectric properties of mammalian tissues from 0.1 to 100 MHz: a summary of recent data. , 1982, Physics in medicine and biology.

[3]  P Liu The P-transform and photoacoustic image reconstruction. , 1998, Physics in medicine and biology.

[4]  J. Shah,et al.  Hall effect imaging , 1998, IEEE Transactions on Biomedical Engineering.

[5]  J. Patrick Reilly,et al.  Electrical Stimulation and Electropathology , 1991 .

[6]  S.W. Smith,et al.  High-speed ultrasound volumetric imaging system. II. Parallel processing and image display , 1991, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[7]  S.W. Smith,et al.  High-speed ultrasound volumetric imaging system. I. Transducer design and beam steering , 1991, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[8]  G E Trahey,et al.  Two-dimensional arrays for medical ultrasound. , 1992, Ultrasonic imaging.

[9]  S. Ballantine,et al.  Reciprocity in Electromagnetic, Mechanical, Acoustical, and Interconnected Systems , 1929, Proceedings of the Institute of Radio Engineers.

[10]  Robert A. Kruger,et al.  Application of thermoacoustic computed tomography to breast imaging , 1999, Medical Imaging.

[11]  S.W. Smith,et al.  Two-Dimensional Arrays for Medical Ultrasound , 1991, IEEE 1991 Ultrasonics Symposium,.

[12]  T. Bowen Radiation-Induced Thermoacoustic Soft Tissue Imaging , 1981 .

[13]  H. Wen,et al.  Volumetric Hall Effect Tomography — A Feasibility Study , 1999, Ultrasonic imaging.

[14]  R. Patterson Bioelectrical Impedance Techniques In Medicine [Book Reviews] , 1998, IEEE Engineering in Medicine and Biology Magazine.

[15]  M. Joy,et al.  In vivo detection of applied electric currents by magnetic resonance imaging. , 1989, Magnetic resonance imaging.

[16]  G.J. Saulnier,et al.  An iterative Newton-Raphson method to solve the inverse admittivity problem , 1998, IEEE Transactions on Biomedical Engineering.