Ketanserin stabilizes blood pressure in conscious spontaneously hypertensive rats

1. It has been demonstrated that blood pressure variability (BPV) is increased in hypertension and related to organ damage. It will be important to lower BPV in the treatment of hypertension. The present study was designed to investigate the effect of ketanserin, a 5‐HT2A receptor antagonist with a weak α1‐adrenoceptor blocking effect, on BPV in conscious spontaneously hypertensive rats (SHR).

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