Sero-epidemiological survey of porcine respiratory coronavirus (PRCV) infection in breeding herds in southeastern Spain.

In 1987 we conducted a sero-epidemiological survey in the Murcia Region (South-East Spain) to discover the prevalence and spread of PRCV-infection among breeding pigs and farms and determine the association between herd size and geographical zone with PRCV-infection. The Murcia Region was divided into four geographical zones and the farms classified by size in four categories. The random sample was statistically representative of both the breeding stock and farms in each geographical zone. We analysed 6,000 breeding pigs from 480 farms. The immunological techniques employed were indirect ELISA and blocking ELISA. The prevalence (P +/- IC) of PRCV-seropositive breeding pigs and infected breeding farms was 14.53 +/- 0.89% and 21.87 +/- 7.83% respectively. On 55% of the infected farms, the prevalence of seropositive breeding pigs was 60-100%. PRCV-infection appears spread throughout the four geographical zones of the Murcia Region. However, a significant association (p less than 0.01) was observed between geographical zone and the prevalence of PRCV-infection. A herd size of greater than 50 breeding pigs had a greater risk (p less than 0.01) of PRCV-infection.

[1]  A. García,et al.  Transmissible gastroenteritis in pigs in south east Spain: prevalence and factors associated with infection , 1993, Veterinary Record.

[2]  R. Woods,et al.  Genetic analysis of porcine respiratory coronavirus, an attenuated variant of transmissible gastroenteritis virus , 1991, Journal of virology.

[3]  P. Britton,et al.  Sequence comparison of the 5' end of mRNA 3 from transmissible gastroenteritis virus and porcine respiratory coronavirus. , 1991, The Journal of general virology.

[4]  H. Laude,et al.  Porcine respiratory coronavirus differs from transmissible gastroenteritis virus by a few genomic deletions. , 1990, The Journal of general virology.

[5]  M. Pensaert,et al.  Intestinal replication of a porcine respiratory coronavirus closely related antigenically to the enteric transmissible gastroenteritis virus , 1990, Veterinary Microbiology.

[6]  M. Pensaert,et al.  Sites of replication of a porcine respiratory coronavirus related to transmissible gastroenteritis virus , 1990, Research in Veterinary Science.

[7]  F. Gebauer,et al.  Antigenic homology among coronaviruses related to transmissible gastroenteritis virus , 1990, Virology.

[8]  P. Vannier.  Disorders induced by the experimental infection of pigs with the porcine respiratory coronavirus (P.R.C.V.). , 1990, Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B.

[9]  P. Have.  Infection with a new porcine respiratory coronavirus in Denmark: serologic differentiation from transmissible gastroenteritis virus using monoclonal antibodies. , 1990, Advances in experimental medicine and biology.

[10]  E. Bottreau,et al.  Natural infection with the porcine respiratory coronavirus induces protective lactogenic immunity against transmissible gastroenteritis , 1989, Veterinary Microbiology.

[11]  J. Boonstra,et al.  Infection with porcine respiratory coronavirus does not fully protect pigs against intestinal transmissible gastroenteritis virus , 1989, Veterinary Record.

[12]  I. Brown,et al.  Pathogenicity of experimental infection with ‘pneumotropic’ porcine coronavirus , 1989, Research in Veterinary Science.

[13]  M. Pensaert,et al.  A competitive inhibition ELISA for the differentiation of serum antibodies from pigs infected with transmissible gastroenteritis virus (TGEV) or with the TGEV-related porcine respiratory coronavirus , 1989, Veterinary Microbiology.

[14]  J. Pol,et al.  Isolation of a TGE virus-related respiratory coronavirus causing fatal pneumonia in pigs , 1989, Veterinary Record.

[15]  J. M. Castro,et al.  Prevalencia de Anticuerpos Frente a Virus Influenza y Coronavirus Respiratorio en Cerdos de Cebo en España , 1989 .

[16]  M. Pensaert,et al.  Antigenic differentiation between transmissible gastroenteritis virus of swine and a related porcine respiratory coronavirus. , 1988, The Journal of general virology.

[17]  J. Hasler,et al.  [Transmissible gastroenteritis (TGE) in Switzerland: antibody persistence after infection and seroepidemiologic studies of the significance of the TGE virus as the cause of diarrhea]. , 1988, Schweizer Archiv für Tierheilkunde.

[18]  I. Brown,et al.  Differentiation of porcine coronavirus from transmissible gastroenteritis virus , 1988, Veterinary Record.

[19]  E. Lange,et al.  Isolierung und erste Charakterisierung eines Coronavirus aus Lungen und Tonsillen klinisch gesunder Schweine , 1988 .

[20]  I. Brown,et al.  New porcine coronavirus? , 1986, Veterinary Record.

[21]  M. Pensaert,et al.  Isolation of a porcine respiratory, non-enteric coronavirus related to transmissible gastroenteritis. , 1986, The Veterinary quarterly.

[22]  D. L. Harris,et al.  A model for determining the prevalence of swine dysentery with preliminary results and an application to pseudorabies and transmissible gastroenteritis prevalence determination , 1983 .

[23]  G. Pritchard.  Observations on clinical aspects of transmissible gastroenteritis of pigs in Norfolk and Suffolk, 1980-81 , 1982, The Veterinary Record.