Folic acid — vitamin and panacea or genetic time bomb?
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[1] C. Davis,et al. Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon. , 2000, The Journal of nutrition.
[2] S. Duthie,et al. DNA instability (strand breakage, uracil misincorporation, and defective repair) is increased by folic acid depletion in human lymphocytes in vitro , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[3] Quanhe Yang,et al. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. , 2000, American journal of epidemiology.
[4] W. Willett,et al. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. , 1997, Cancer research.
[5] D. Roberts,et al. Clotting and hemorrhage in the placenta--a delicate balance. , 2002, The New England journal of medicine.
[6] E. Pennisi. Evo-Devo Devotees Eye Ocular Origins and More , 2002, Science.
[7] M. Lucock,et al. In vivo characterization of the absorption and biotransformation of pteroylmonoglutamic acid in man: a model for future studies. , 1989, Biochemical medicine and metabolic biology.
[8] B. Toone,et al. Enhancement of recovery from psychiatric illness by methylfolate , 1992, British Journal of Psychiatry.
[9] Eskes Tk. Homocysteine and human reproduction. , 2000 .
[10] M. Lucock,et al. Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate. , 2004, Journal of the National Cancer Institute.
[11] M. Lucock,et al. A critical role for B-vitamin nutrition in human developmental and evolutionary biology , 2003 .
[12] N. Jablonski,et al. The evolution of human skin coloration. , 2000, Journal of human evolution.
[13] Jim Kaput,et al. Diet-disease gene interactions. , 2004, Nutrition.
[14] H. Blom,et al. Genetic risk factor for unexplained recurrent early pregnancy loss , 1997, The Lancet.
[15] M. Lucock,et al. Methionine synthase polymorphism A2756G is associated with susceptibility for thromboembolic events and altered B vitamin/thiol metabolism. , 2002, Haematologica.
[16] Donald Macleod,et al. A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA , 1985, Cell.
[17] W. Cooke,et al. Serum folates in man. , 1977, Journal of clinical pathology.
[18] M. Leppert,et al. Methylenetetrahydrofolate reductase, diet, and risk of colon cancer. , 1999, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[19] T. Tamura,et al. Changes in frequencies of heterozygous thermolabile 5,10-methylenetetrahydrofolate reductase gene in fetuses with neural tube defects , 2002, Journal of medical genetics.
[20] M. Goggins,et al. Unmetabolized folic acid in serum: acute studies in subjects consuming fortified food and supplements. , 1997, The American journal of clinical nutrition.
[21] G. Russo,et al. The relationship between riboflavin and plasma total homocysteine in the Framingham Offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene. , 2002, The Journal of nutrition.
[22] H. Blom,et al. Hyperhomocysteinemia: a risk factor in women with unexplained recurrent early pregnancy loss. , 1993, Fertility and sterility.
[23] A. Reyes-Engel,et al. Genetic selection and folate intake during pregnancy , 1998, The Lancet.
[24] W. Loomis. Skin-Pigment Regulation of Vitamin-D Biosynthesis in Man , 1967, Science.
[25] G. Zielhuis,et al. Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial. , 2002, Fertility and sterility.
[26] L. Gu,et al. Involvement of DNA mismatch repair in folate deficiency-induced apoptosis small star, filled. , 2002, The Journal of nutritional biochemistry.
[27] A. Rajkovic,et al. Elevated Homocyst(e)ine Levels With Preeclampsia , 1997, Obstetrics and gynecology.
[28] D. Albanes,et al. Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers. , 2001, American journal of epidemiology.
[29] M. Lucock. Is folic acid the ultimate functional food component for disease prevention? , 2004, BMJ : British Medical Journal.
[30] Sang-Woon Choi,et al. Gene-nutrient interactions and DNA methylation. , 2002, The Journal of nutrition.
[31] G. Wells,et al. Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms: an examination of C677T and A1298C mutations. , 2000, American journal of human genetics.
[32] C. Ong,et al. The associations among semen quality, oxidative DNA damage in human spermatozoa and concentrations of cadmium, lead and selenium in seminal plasma. , 2003, Mutation research.
[33] K. El-Bayoumy,et al. The protective role of selenium on genetic damage and on cancer. , 2001, Mutation research.
[34] Y. Ikeda,et al. The frequent 5,10-methylenetetrahydrofolate reductase C677T polymorphism is associated with a common haplotype in whites, Japanese, and Africans. , 2002, American journal of human genetics.
[35] A. Bird,et al. Number of CpG islands and genes in human and mouse. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[36] R. Matthews,et al. The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia , 1999, Nature Structural Biology.
[37] H. Ohwada,et al. Experimental study of the therapeutic effects of folate, vitamin A, and vitamin B12 on squamous metaplasia of the bronchial epithelium , 1993, Cancer.
[38] M. Guy,et al. Vitamin D Receptor Gene Polymorphisms and Breast Cancer Risk , 2004, Clinical Cancer Research.
[39] V. L. Wilson,et al. Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome. , 1999, The American journal of clinical nutrition.
[40] M. Gnant,et al. Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study , 1991, The Lancet.
[41] Adrian Bird,et al. The essentials of DNA methylation , 1992, Cell.
[42] R. Matthews,et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase , 1995, Nature Genetics.
[43] E. H. Reynolds,et al. Enhancement of recovery from psychiatric illness by methylfolate , 1990, The Lancet.
[44] J. M. Rogers,et al. Folate and Human Development , 2002, Humana Press.
[45] P. Gillies. Nutrigenomics: the Rubicon of molecular nutrition. , 2003, Journal of the American Dietetic Association.
[46] S. Vollset,et al. Riboflavin as a determinant of plasma total homocysteine: effect modification by the methylenetetrahydrofolate reductase C677T polymorphism. , 2000, Clinical chemistry.
[47] 亀井 太美子. Experimental study of the therapeutic effects of folate, vitamin A, and vitamin B[12] on squamous metaplasia of the bronchial epithelium , 1995 .
[48] D. B. Wilson,et al. Estimated folate intakes: data updated to reflect food fortification, increased bioavailability, and dietary supplement use. , 1999, The American journal of clinical nutrition.
[49] L. Chambless,et al. Vitamin intake: a possible determinant of plasma homocyst(e)ine among middle-aged adults. , 1997, Annals of epidemiology.
[50] G. Omenn,et al. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. , 1995, JAMA.
[51] Prevention of neural tube defects: Results of the Medical Research Council vitamin study , 1991 .
[52] S. Kersten,et al. Nutrigenomics: goals and strategies , 2003, Nature Reviews Genetics.
[53] Soo-Sang Kang,et al. Thermolabile Methylenetetrahydrofolate Reductase , 1997 .
[54] G. Morgan,et al. Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[55] J. D. Vries,et al. Underlying disorders associated with severe early-onset preeclampsia. , 1995, American journal of obstetrics and gynecology.
[56] C. Butterworth,et al. Folate status, women's health, pregnancy outcome, and cancer. , 1993, Journal of the American College of Nutrition.
[57] J. Gris,et al. Case-control Study of the Frequency of Thrombophilic Disorders in Couples with Late Foetal Loss and no Thrombotic Antecedent , 1999, Thrombosis and Haemostasis.
[58] M. Lucock,et al. The impact of phenylketonuria on folate metabolism. , 2002, Molecular genetics and metabolism.
[59] G A Colditz,et al. A prospective study of folate intake and the risk of breast cancer. , 1999, JAMA.
[60] J. Mason,et al. Folate depletion impairs DNA excision repair in the colon of the rat , 1998, Gut.
[61] H. McNulty,et al. Impaired functioning of thermolabile methylenetetrahydrofolate reductase is dependent on riboflavin status: implications for riboflavin requirements. , 2002, The American journal of clinical nutrition.
[62] K. Aoki. Sexual selection as a cause of human skin colour variation: Darwin's hypothesis revisited , 2002, Annals of human biology.
[63] M. Levene,et al. Optimisation of chromatographic conditions for the determination of folates in foods and biological tissues for nutritional and clinical work , 1995 .
[64] R Clarke,et al. Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. , 1998, Archives of neurology.
[65] M. den Heyer,et al. Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida , 1995, The Lancet.
[66] J. Mills,et al. Methylenetetrahydrofolate reductase thermolabile variant and oral clefts. , 1999, American journal of medical genetics.
[67] R. Matthews,et al. Interactions of pig liver methylenetetrahydrofolate reductase with methylenetetrahydropteroylpolyglutamate substrates and with dihydropteroylpolyglutamate inhibitors. , 1980, Biochemistry.