The First Fatal Case of Chloroform Anesthesia in the United States
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Chloroform anesthesia was introduced by Simpson of Edinburgh in November, 1847.In the United States, this agent first successfully used for surgical anesthesia by C. A. Harris of Baltimore on about December 20, 1847.Only two months passed, however, before chloroform anesthesia claimed its first fatality in this country. This case happened to Mrs. Simmonds of Cincinnati on February 23, 1848.
[1] A. Matsuki,et al. The Introduction of Chloroform Anesthesia in the United States , 1974, Anesthesia and analgesia.
[2] N. M. Greene. A consideration of factors in the discovery of anesthesia and their effects on its development. , 1971, Anesthesiology.
[3] J. Simpson. ON A NEW ANÆSTHETIC AGENT, MORE EFFICIENT THAN SULPHURIC ETHER. , 1847 .