Gut microbiota: a potential new territory for drug targeting
暂无分享,去创建一个
Jeremy K. Nicholson | Liping Zhao | J. Nicholson | Liping Zhao | Houkai Li | W. Jia | Wei Jia | Houkai Li
[1] S. Pettersson,et al. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-γ and RelA , 2004, Nature Immunology.
[2] L. Maunula,et al. Prophylactic Lactobacillus GGReduces Antibiotic-Associated Diarrhea in Children With Respiratory Infections: A Randomized Study , 1999, Pediatrics.
[3] P. Turnbaugh,et al. Microbial ecology: Human gut microbes associated with obesity , 2006, Nature.
[4] M. Pop,et al. Metagenomic Analysis of the Human Distal Gut Microbiome , 2006, Science.
[5] J. Nicholson,et al. Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics , 2002, Nature Medicine.
[6] S. Akira,et al. Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis. , 2004, Gastroenterology.
[7] P. Mannon,et al. The fundamental basis of inflammatory bowel disease. , 2007, The Journal of clinical investigation.
[8] R. Williams,et al. Effect of intestinal microflora on the urinary metabolic profile of rats: a 1 H-nuclear magnetic resonance spectroscopy study , 2002, Xenobiotica; the fate of foreign compounds in biological systems.
[9] I. Wilson,et al. Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism , 2003, Nature Reviews Drug Discovery.
[10] F. Guarner,et al. Gut flora in health and disease , 2003, The Lancet.
[11] J. Hotz. [Prevention of antibiotic-associated diarrhea by Saccharomyces boulardii: a prospective study]. , 1990, Zeitschrift fur Gastroenterologie.
[12] W. Walker,et al. Probiotics and prebiotics: role in clinical disease states. , 2005, Advances in pediatrics.
[13] Tie Zhao,et al. Simultaneous determination of 17 ginsenosides in rat urine by ultra performance liquid chromatography-mass spectrometry with solid-phase extraction. , 2007, Analytica chimica acta.
[14] Mark M Huycke,et al. Bacteria-Induced Intestinal Cancer in Mice with Disrupted Gpx1 and Gpx2 Genes , 2004, Cancer Research.
[15] Liping Zhao,et al. Pharmacometabonomic phenotyping reveals different responses to xenobiotic intervention in rats. , 2007, Journal of proteome research.
[16] J. Gordon,et al. Honor thy symbionts , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[17] E. Purdom,et al. Diversity of the Human Intestinal Microbial Flora , 2005, Science.
[18] R. Davis,et al. Association Between Streptococcal Infection and Obsessive-Compulsive Disorder, Tourette's Syndrome, and Tic Disorder , 2005, Pediatrics.
[19] I. Wilson,et al. Effect of diet on the urinary excretion of hippuric acid and other dietary-derived aromatics in rat. A complex interaction between diet, gut microflora and substrate specificity. , 1998, Xenobiotica; the fate of foreign compounds in biological systems.
[20] I. Saiki,et al. In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration. , 1997, Oncology research.
[21] M. Robertson,et al. Increased Antistreptococcal Antibody Titers and Anti—Basal Ganglia Antibodies in Patients With Tourette Syndrome: Controlled Cross-Sectional Study , 2006, Journal of child neurology.
[22] P. Long,et al. Biomedicinals from the phytosymbionts of marine invertebrates: a molecular approach. , 2007, Methods.
[23] R. G. Joosten,et al. Persistence of DNA studied in different ex vivo and in vivo rat models simulating the human gut situation. , 2004, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[24] J. Handelsman. Metagenomics: Application of Genomics to Uncultured Microorganisms , 2004, Microbiology and Molecular Biology Reviews.
[25] Ting Wang,et al. The gut microbiota as an environmental factor that regulates fat storage. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[26] M. Tomita,et al. Bifidobacterium longum, a lactic acid-producing intestinal bacterium inhibits colon cancer and modulates the intermediate biomarkers of colon carcinogenesis. , 1997, Carcinogenesis.
[27] E. Mardis,et al. An obesity-associated gut microbiome with increased capacity for energy harvest , 2006, Nature.
[28] R. Kerwin,et al. Role of Chronic Infection and Inflammation in the Gastrointestinal Tract in the Etiology and Pathogenesis of Idiopathic Parkinsonism , 2005, Helicobacter.
[29] P. Malfertheiner,et al. Helicobacter pylori eradication and gastric ulcer healing — comparison of three pantoprazole‐based triple therapies , 2003, Alimentary pharmacology & therapeutics.
[30] M. McCarthy,et al. Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice , 2006, Proceedings of the National Academy of Sciences.
[31] A. Gunatilaka. Natural products from plant-associated microorganisms: distribution, structural diversity, bioactivity, and implications of their occurrence. , 2006, Journal of natural products.
[32] Justin C.Y. Wu,et al. Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: a randomised trial , 2002, The Lancet.
[33] S. Okada,et al. Mutagenicity of dimethylated metabolites of inorganic arsenics. , 1989, Chemical & pharmaceutical bulletin.
[34] A. Andoh,et al. Therapeutic approaches targeting intestinal microflora in inflammatory bowel disease. , 2006, World journal of gastroenterology.
[35] T. Matsuzaki,et al. Prevention of onset in an insulin‐dependent diabetes mellitus model, NOD mice, by oral feeding of Lactobacillus casei , 1997, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[36] M. Mendall,et al. Antibiotic use, childhood affluence and irritable bowel syndrome (IBS) , 1998, European journal of gastroenterology & hepatology.
[37] R. Wilson,et al. Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut , 2007, Proceedings of the National Academy of Sciences.
[38] J. Rhodes,et al. Bacteria in the pathogenesis of inflammatory bowel disease , 2006, Current opinion in infectious diseases.
[39] X. Hua,et al. Inter-species transplantation of gut microbiota from human to pigs , 2007, The ISME Journal.
[40] G. Reid,et al. Modulation of the microbial ecology of the human colon by probiotics, prebiotics and synbiotics to enhance human health: an overview of enabling science and potential applications. , 2005, FEMS microbiology ecology.
[41] G. Macfarlane,et al. Intestinal bacteria and ulcerative colitis. , 2003, Current issues in intestinal microbiology.
[42] T. Hartung,et al. Enhanced antiinflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[43] M. Wilcox. Clostridium difficile infection and pseudomembranous colitis , 2003 .
[44] M. Kokkinidis,et al. Conserved features of type III secretion , 2004, Cellular microbiology.
[45] T. Matsuzaki,et al. Effect of oral administration of Lactobacillus casei on alloxan‐induced diabetes in mice , 1997, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[46] S. Walsh,et al. Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial , 2005, Gut.
[47] R. Yamazaki,et al. Antidiabetic effects of an oral administration of Lactobacillus casei in a non-insulin-dependent diabetes mellitus (NIDDM) model using KK-Ay mice. , 1997, Endocrine journal.
[48] M. Wilcox. Gastrointestinal disorders and the critically ill. Clostridium difficile infection and pseudomembranous colitis. , 2003, Best practice & research. Clinical gastroenterology.
[49] C. Surawicz,et al. The search for a better treatment for recurrent Clostridium difficile disease: use of high-dose vancomycin combined with Saccharomyces boulardii. , 2000, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[50] F. Shanahan,et al. Probiotic impact on microbial flora, inflammation and tumour development in IL‐10 knockout mice , 2001, Alimentary pharmacology & therapeutics.
[51] F. Shanahan,et al. The gut flora as a forgotten organ , 2006, EMBO reports.
[52] A. Hosono,et al. Antidiabetic Effect of Lactobacillus GG in Streptozotocin-induced Diabetic Rats , 2003, Bioscience, biotechnology, and biochemistry.
[53] Lynn K. Carmichael,et al. A Genomic View of the Human-Bacteroides thetaiotaomicron Symbiosis , 2003, Science.
[54] G R Gibson,et al. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. , 1995, The Journal of nutrition.
[55] H. Yadav,et al. Antidiabetic effect of probiotic dahi containing Lactobacillus acidophilus and Lactobacillus casei in high fructose fed rats. , 2007, Nutrition.
[56] Elaine Holmes,et al. The challenges of modeling mammalian biocomplexity , 2004, Nature Biotechnology.
[57] J. Handelsman,et al. Metagenomics: genomic analysis of microbial communities. , 2004, Annual review of genetics.
[58] Minjun Chen,et al. Application of ethyl chloroformate derivatization for gas chromatography-mass spectrometry based metabonomic profiling. , 2007, Analytica chimica acta.
[59] C. Hadley. The infection connection , 2006, EMBO reports.
[60] J. Lindon,et al. Pharmaco-metabonomic phenotyping and personalized drug treatment , 2006, Nature.
[61] M. Tanner,et al. Metabonomic investigations in mice infected with Schistosoma mansoni: an approach for biomarker identification. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[62] Timothy M. D. Ebbels,et al. Toxicity classification from metabonomic data using a density superposition approach: ‘CLOUDS’ , 2003 .
[63] H. Harmsen,et al. Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes? , 2006, Diabetologia.
[64] K. Fellermann,et al. Induction of Human β-Defensin 2 by the Probiotic Escherichia coli Nissle 1917 Is Mediated through Flagellin , 2007, Infection and Immunity.
[65] I. Wilson,et al. Gut microorganisms, mammalian metabolism and personalized health care , 2005, Nature Reviews Microbiology.