Variation in rice cadmium related to human exposure.

Cereal grains are the dominant source of cadmium in the human diet, with rice being to the fore. Here we explore the effect of geographic, genetic, and processing (milling) factors on rice grain cadmium and rice consumption rates that lead to dietary variance in cadmium intake. From a survey of 12 countries on four continents, cadmium levels in rice grain were the highest in Bangladesh and Sri Lanka, with both these countries also having high per capita rice intakes. For Bangladesh and Sri Lanka, there was high weekly intake of cadmium from rice, leading to intakes deemed unsafe by international and national regulators. While genetic variance, and to a lesser extent milling, provide strategies for reducing cadmium in rice, caution has to be used, as there is environmental regulation as well as genetic regulation of cadmium accumulation within rice grains. For countries that import rice, grain cadmium can be controlled by where that rice is sourced, but for countries with subsistence rice economies that have high levels of cadmium in rice grain, agronomic and breeding strategies are required to lower grain cadmium.

[1]  Akira Kawasaki,et al.  Effects of water management on cadmium and arsenic accumulation and dimethylarsinic acid concentrations in Japanese rice. , 2009, Environmental science & technology.

[2]  Lizhong Xiong,et al.  Genetic mapping of the rice ionome in leaves and grain: identification of QTLs for 17 elements including arsenic, cadmium, iron and selenium , 2010, Plant and Soil.

[3]  G. Duan,et al.  Environmental and genetic control of arsenic accumulation and speciation in rice grain: comparing a range of common cultivars grown in contaminated sites across Bangladesh, China, and India. , 2009, Environmental science & technology.

[4]  H. Horiguchi.  [Current status of cadmium exposure among Japanese, especially regarding the safety standard for cadmium concentration in rice and adverse effects on proximal renal tubular function observed in farmers exposed to cadmium through consumption of self-grown rice]. , 2012, Nihon eiseigaku zasshi. Japanese journal of hygiene.

[5]  T. Nishio,et al.  Analysis of QTL for lowering cadmium concentration in rice grains from ‘LAC23’ , 2011 .

[6]  C. Padungtod,et al.  Cadmium induced renal dysfunction among residents of rice farming area downstream from a zinc-mineralized belt in Thailand. , 2010, Toxicology letters.

[7]  Yong-guan Zhu,et al.  Occurrence and partitioning of cadmium, arsenic and lead in mine impacted paddy rice: Hunan, China. , 2009, Environmental science & technology.

[8]  N. Ziadi,et al.  Excessive sulfur supply reduces cadmium accumulation in brown rice (Oryza sativa L.). , 2010, Environmental pollution.

[9]  G. Nordberg,et al.  Renal effects evolution in a Chinese population after reduction of cadmium exposure in rice. , 2008, Environmental research.

[10]  Mark G. M. Aarts,et al.  Plant science: the key to preventing slow cadmium poisoning. , 2013, Trends in plant science.

[11]  Yongzhong Qian,et al.  Concentrations of cadmium, lead, mercury and arsenic in Chinese market milled rice and associated population health risk , 2010 .

[12]  M. Yano,et al.  A major quantitative trait locus controlling cadmium translocation in rice (Oryza sativa). , 2009, The New phytologist.

[13]  Prosun Bhattacharya,et al.  Consumption of brown rice: a potential pathway for arsenic exposure in rural Bengal. , 2012, Environmental science & technology.

[14]  N. Yamaji,et al.  Nramp5 Is a Major Transporter Responsible for Manganese and Cadmium Uptake in Rice[C][W] , 2012, Plant Cell.

[15]  F. Zhao,et al.  Arsenic and rice , 2012 .

[16]  J. Bandara,et al.  Chronic renal failure among farm families in cascade irrigation systems in Sri Lanka associated with elevated dietary cadmium levels in rice and freshwater fish (Tilapia) , 2008, Environmental geochemistry and health.

[17]  J. J. Mortvedt,et al.  STUDIES ON THE CHEMICAL FORM OF CADMIUM CONTAMINANTS IN PHOSPHATE FERTILIZERS , 1982 .

[18]  K. Ljung,et al.  High concentrations of essential and toxic elements in infant formula and infant foods - A matter of concern. , 2011, Food chemistry.

[19]  A. Meharg,et al.  Inorganic arsenic and trace elements in Ghanaian grain staples. , 2011, Environmental pollution.

[20]  M. Yano,et al.  A major quantitative trait locus for increasing cadmium-specific concentration in rice grain is located on the short arm of chromosome 7 , 2009, Journal of experimental botany.

[21]  G. An,et al.  Low cadmium (LCD), a novel gene related to cadmium tolerance and accumulation in rice , 2009, Journal of experimental botany.

[22]  Jianguo G. Wu,et al.  Genotypic differences in arsenic, mercury, lead and cadmium in milled rice (Oryza sativa L.) , 2012, International journal of food sciences and nutrition.

[23]  T. Matoh,et al.  Current situation of cadmium-polluted paddy soil, rice and soybean in the Mae Sot District, Tak Province, Thailand , 2012 .

[24]  Yongming Luo,et al.  Cadmium distribution in rice plants grown in three different soils after application of pig manure with added cadmium , 2012, Environmental Geochemistry and Health.

[25]  A. Meharg,et al.  Getting to the bottom of arsenic standards and guidelines. , 2010, Environmental science & technology.

[26]  T. Arao,et al.  [Reducing cadmium content of rice grains by means of flooding and a few problems]. , 2012, Nihon eiseigaku zasshi. Japanese journal of hygiene.