Implementing Patient-Reported Outcome Measures in Clinical Breast Cancer Care: A Systematic Review.

BACKGROUND Patient-reported outcome measures (PROMs) are increasingly being used to improve care delivery and are becoming part of routine clinical practice. OBJECTIVE This systematic review aims to give an overview of PROM administration methods and their facilitators and barriers in breast cancer clinical practice. METHODS A systematic literature search was conducted in Embase, MEDLINE, PsycINFO, Cochrane Central, CINAHL, and Web of Science for potentially relevant articles from study inception to November 2017. Reference lists of screened reviews were also checked. After inclusion of relevant articles, data were extracted and appraised by 2 investigators. RESULTS A total of 2311 articles were screened, of which 34 eligible articles were ultimately included. Method and frequency of PROM collection varied between studies. The majority of studies described a promising effect of PROM collection on patients (adherence, symptom distress, quality of life, acceptability, and satisfaction), providers (willingness to comply, clinical decision making, symptom management), and care process or system outcomes (referrals, patient-provider communication, hospital visits). A limited number of facilitators and barriers were identified, primarily of a technical and behavioral nature. CONCLUSION Although interpreting the impact of PROM collection in breast cancer care is challenging owing to considerations of synergistic (multicomponent) interventions and generalizability issues, this review found that systematic PROM collection has a promising impact on patients, providers, and care processes/ systems. Further standardization and reporting on method and frequency of PROM collection might help increase the effectiveness of PROM interventions and is warranted to enhance their overall impact.

[1]  Jack Chen,et al.  A systematic review of the impact of routine collection of patient reported outcome measures on patients, providers and health organisations in an oncologic setting , 2013, BMC Health Services Research.

[2]  C. Chronaki,et al.  eHealth Trends in Europe 2005-2007: A Population-Based Survey , 2008, Journal of medical Internet research.

[3]  Barbara Given,et al.  A Pilot Study of an Automated Voice Response System and Nursing Intervention to Monitor Adherence to Oral Chemotherapy Agents , 2009, Cancer nursing.

[4]  Richard Harding,et al.  Implementing patient-reported outcome measures in palliative care clinical practice: A systematic review of facilitators and barriers , 2014, Palliative medicine.

[5]  Ramesh Farzanfar,et al.  Automated monitoring of symptoms during ambulatory chemotherapy and oncology providers’ use of the information: a randomized controlled clinical trial , 2014, Supportive Care in Cancer.

[6]  N. Aaronson,et al.  Health-related quality-of-life assessments and patient-physician communication: a randomized controlled trial. , 2002, JAMA.

[7]  P. Selby,et al.  Impact of patient-reported outcomes in oncology: a longitudinal analysis of patient-physician communication. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[8]  Cornelia M. Ruland,et al.  Evaluation of different features of an eHealth application for personalized illness management support: Cancer patients' use and appraisal of usefulness , 2013, Int. J. Medical Informatics.

[9]  P. Fasching,et al.  Willingness of Patients with Breast Cancer in the Adjuvant and Metastatic Setting to Use Electronic Surveys (ePRO) Depends on Sociodemographic Factors, Health-related Quality of Life, Disease Status and Computer Skills , 2016, Geburtshilfe und Frauenheilkunde.

[10]  Bob Wong,et al.  Automated home monitoring and management of patient‐reported symptoms during chemotherapy: results of the symptom care at home RCT , 2017, Cancer medicine.

[11]  M. Porter,et al.  Standardizing Patient Outcomes Measurement. , 2016, The New England journal of medicine.

[12]  Shirley M Moore,et al.  Comparing Effects in Regular Practice of E-Communication and Web-Based Self-Management Support Among Breast Cancer Patients: Preliminary Results From a Randomized Controlled Trial , 2014, Journal of medical Internet research.

[13]  Deborah Schrag,et al.  Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[14]  N. Hjollund,et al.  Response Rate and Completeness of Questionnaires: A Randomized Study of Internet Versus Paper-and-Pencil Versions , 2007, Journal of medical Internet research.

[15]  W. V. van Harten,et al.  An interactive portal to empower cancer survivors: a qualitative study on user expectations , 2015, Supportive Care in Cancer.

[16]  C. Earle,et al.  Does routine symptom screening with ESAS decrease ED visits in breast cancer patients undergoing adjuvant chemotherapy? , 2015, Supportive Care in Cancer.

[17]  P. Butow,et al.  Does routine psychological screening of newly diagnosed rural cancer patients lead to better patient outcomes? Results of a pilot study. , 2009, The Australian journal of rural health.

[18]  Malgorzata Roos,et al.  A Mobile App to Stabilize Daily Functional Activity of Breast Cancer Patients in Collaboration With the Physician: A Randomized Controlled Clinical Trial , 2016, Journal of medical Internet research.

[19]  N. Kearney,et al.  Evaluation of a mobile phone-based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity , 2009, Supportive Care in Cancer.

[20]  Albert W Wu,et al.  Feasibility and value of PatientViewpoint: a web system for patient‐reported outcomes assessment in clinical practice , 2013, Psycho-oncology.

[21]  C. Acquadro,et al.  Interviewing to develop Patient-Reported Outcome (PRO) measures for clinical research: eliciting patients’ experience , 2014, Health and Quality of Life Outcomes.

[22]  Geoffrey Liu,et al.  Feasibility and diagnostic accuracy of the Patient‐Reported Outcomes Measurement Information System (PROMIS) item banks for routine surveillance of sleep and fatigue problems in ambulatory cancer care , 2016, Cancer.

[23]  D. Howell,et al.  Patient-reported outcomes in routine cancer clinical practice: a scoping review of use, impact on health outcomes, and implementation factors. , 2015, Annals of oncology : official journal of the European Society for Medical Oncology.

[24]  D. Lavallee,et al.  Prioritizing Patient‐Reported Outcomes in Breast Cancer Surgery Quality Improvement , 2017, The breast journal.

[25]  N. Aaronson,et al.  Use of health‐related quality‐of‐life assessments in daily clinical oncology nursing practice , 2008, Cancer.

[26]  P. Bindels,et al.  Using the symptom monitor in a randomized controlled trial: the effect on symptom prevalence and severity. , 2006, Journal of pain and symptom management.

[27]  C. Cleeland,et al.  Automated pain intervention for underserved minority women with breast cancer , 2015, Cancer.

[28]  R. Sanson-Fisher,et al.  Does routine assessment and real-time feedback improve cancer patients' psychosocial well-being? , 2006, European journal of cancer care.

[29]  N. Aaronson,et al.  Use of patient-reported outcomes in clinical practice , 2009, The Lancet.

[30]  James J. Yang,et al.  Examining the Impact of a Web-Based Intervention to Promote Patient Activation in Chemotherapy-Induced Peripheral Neuropathy Assessment and Management , 2017, Journal of Cancer Education.

[31]  L. Esserman,et al.  SIS.NET: A randomized controlled trial evaluating a web‐based system for symptom management after treatment of breast cancer , 2015, Cancer.

[32]  David Cella,et al.  The talking touchscreen: A new approach to outcomes assessment in low literacy , 2004, Psycho-oncology.

[33]  N. Dean,et al.  A five year experience of measuring clinical effectiveness in a breast reconstruction service using the BREAST-Q patient reported outcomes measure: A cohort study. , 2016, Journal of plastic, reconstructive & aesthetic surgery : JPRAS.

[34]  Carol J. Hermansen-Kobulnicky.  Symptom-monitoring behaviors of rural cancer patients and survivors , 2009, Supportive Care in Cancer.

[35]  Anthony L Back,et al.  Electronic self-report assessment for cancer and self-care support: results of a multicenter randomized trial. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[36]  Nandita Mitra,et al.  Patient online self-reporting of toxicity symptoms during chemotherapy. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[37]  R. Berenson,et al.  Grading a physician's value--the misapplication of performance measurement. , 2013, The New England journal of medicine.

[38]  A. Girgis,et al.  Impact of two supportive care interventions on anxiety, depression, quality of life, and unmet needs in patients with nonlocalized breast and colorectal cancers. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[39]  Bryant T Karras,et al.  Enhancing patient-provider communication with the electronic self-report assessment for cancer: a randomized trial. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[40]  G. Velikova,et al.  Development of an integrated electronic platform for patient self-report and management of adverse events during cancer treatment , 2017, Annals of oncology : official journal of the European Society for Medical Oncology.

[41]  Mei R Fu,et al.  mHealth self-care interventions: managing symptoms following breast cancer treatment. , 2016, mHealth.

[42]  A. Abernethy,et al.  Using patient reported outcomes in oncology clinical practice , 2016, Scandinavian journal of pain.

[43]  R. Fitzpatrick,et al.  Impact of patient-reported outcome measures on routine practice: a structured review. , 2006, Journal of evaluation in clinical practice.

[44]  N. Frasure-smith,et al.  Randomized trial of a psychologic distress screening program after breast cancer: effects on quality of life. , 1996, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[45]  A. Wu,et al.  Improving an electronic system for measuring PROs in routine oncology practice , 2015, Journal of Cancer Survivorship.

[46]  Deborah Schrag,et al.  Feasibility of long-term patient self-reporting of toxicities from home via the Internet during routine chemotherapy. , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[47]  Kai Lin,et al.  Application of Information Technology: Evaluation of an Online Platform for Cancer Patient Self-reporting of Chemotherapy Toxicities , 2007, J. Am. Medical Informatics Assoc..

[48]  A. Wu,et al.  Relevant content for a patient-reported outcomes questionnaire for use in oncology clinical practice: Putting doctors and patients on the same page , 2010, Quality of Life Research.

[49]  P. Ganz,et al.  Managing menopausal symptoms in breast cancer survivors: results of a randomized controlled trial. , 2000, Journal of the National Cancer Institute.

[50]  Ronald C. Chen,et al.  Integrating Patient-Reported Outcome Measures into Routine Cancer Care: Cancer Patients’ and Clinicians’ Perceptions of Acceptability and Value , 2015, EGEMS.

[51]  Thomas J. Smith,et al.  A Standard Set of Value-Based Patient-Centered Outcomes for Breast Cancer: The International Consortium for Health Outcomes Measurement (ICHOM) Initiative , 2017, JAMA oncology.

[52]  Ethan Basch,et al.  Patient-reported outcomes and the evolution of adverse event reporting in oncology. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[53]  M. Kris,et al.  Overall Survival Results of a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring During Routine Cancer Treatment , 2017, JAMA.

[54]  P. Selby,et al.  Patients report improvements in continuity of care when quality of life assessments are used routinely in oncology practice: secondary outcomes of a randomised controlled trial. , 2010, European journal of cancer.

[55]  Byungtae Lee,et al.  Depression Screening Using Daily Mental-Health Ratings from a Smartphone Application for Breast Cancer Patients , 2016, Journal of medical Internet research.

[56]  W. Dudley,et al.  Pilot Testing a Web-Based System for the Assessment and Management of Chemotherapy-Induced Peripheral Neuropathy , 2017, Computers, informatics, nursing : CIN.

[57]  Nancy Breen,et al.  Use of health‐related and cancer‐specific support groups among adult cancer survivors , 2007, Cancer.

[58]  David Cella,et al.  Assessment is not enough: a randomized controlled trial of the effects of HRQL assessment on quality of life and satisfaction in oncology clinical practice , 2007, Psycho-oncology.

[59]  Meurig Sage,et al.  Perceptions of the use of a remote monitoring system in patients receiving palliative care at home. , 2008, International journal of palliative nursing.

[60]  Stanley E. Kaufman,et al.  Electronic collection of health-related quality of life data: Validity, time benefits, and patient preference , 2004, Quality of Life Research.

[61]  Yul Ha Min,et al.  Daily Collection of Self-Reporting Sleep Disturbance Data via a Smartphone App in Breast Cancer Patients Receiving Chemotherapy: A Feasibility Study , 2014, Journal of medical Internet research.

[62]  M. Rothmund,et al.  Quality of life profile: from measurement to clinical application. , 2002, Breast.

[63]  L. Carlson,et al.  Screening for distress in lung and breast cancer outpatients: a randomized controlled trial. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[64]  A. Jemal,et al.  Global Cancer Statistics , 2011 .

[65]  Jeffrey A. Alexander,et al.  Review: What Can We Learn From Quality Improvement Research? , 2009 .

[66]  Amy P Abernethy,et al.  Review of electronic patient-reported outcomes systems used in cancer clinical care. , 2014, Journal of oncology practice.

[67]  A. Abernethy,et al.  Feasibility and acceptability to patients of a longitudinal system for evaluating cancer-related symptoms and quality of life: pilot study of an e/Tablet data-collection system in academic oncology. , 2009, Journal of pain and symptom management.

[68]  L. Esserman,et al.  The impact of an electronic health questionnaire on symptom management and behavior reporting for breast cancer survivors , 2012, Breast Cancer Research and Treatment.

[69]  Galina Velikova,et al.  Measuring quality of life in routine oncology practice improves communication and patient well-being: a randomized controlled trial. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[70]  L. Lechner,et al.  Psychosocial screening effects on health‐related outcomes in patients receiving radiotherapy. A cluster randomised controlled trial , 2013, Psycho-oncology.