Analysis of Adult Nephrectomies at the Komfo Anokye Teaching Hospital, Kumasi, Ghana

Objective: To evaluate open nephrectomies performed in adults over a five year period at the Komfo Anokye Teaching Hospital (KATH) and to compare our experience with findings in the literature. Materials and Methods: This was a prospective, cross-sectional, hospital based study of all adults undergoing nephrectomy from October 2012 to September 2017 at KATH. We obtained data on patient demographics, clinical presentation, laboratory and imaging results, laterality of the disease, and indication for nephrectomy, complications and histopathology of nephrectomy specimen. The data was analyzed using PASW Statistics for Windows, Version 19.0. Chicago: SPSS Inc. Results: Thirty three (33) adult nephrectomies were performed over the study period. There were 18 males (54.50%) and 15 females (45.50%) with an age range of 16 years to 80 years. The modal age range for renal malignancies was 31 - 40 years accounting for 36.40% of adult nephrectomies. Flank pain (75.80%), haematuria (54.60%) and flank mass (51.50%) were the predominant presenting complaints. Malignant renal tumours accounted for 22 (66.70%) of the nephrectomies followed by neglected Pelvi-Ureteric Junction Obstruction (PUJO)—7 (21.20%); two (6.10%) nephrectomies were due to trauma and one (3.00%) for emphysematous pyelonephritis. Conclusion: Renal cell carcinoma constitutes the main indication for adult nephrectomy at KATH followed by neglected PUJO. Most of the patients with renal tumours were young and also presented late.

[1]  A. Diallo,et al.  Management of Renal Cell Carcinoma—Current Practice in Sub-Saharan Africa , 2019, Journal of kidney cancer and VHL.

[2]  A. Bello,et al.  Peculiarities of renal cell carcinoma in young adults , 2018 .

[3]  O. Ekeke,et al.  Open Nephrectomy: Experience in a Nigerian Teaching Hospital , 2018 .

[4]  S. Collins,et al.  Adult Wilms’ Tumour: Case Report and Review of Literature , 2016, Journal of kidney cancer and VHL.

[5]  J. Mensah,et al.  Nephrectomy in adults: Experience at the Korle Bu Teaching Hospital, Accra, Ghana. , 2015, Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.

[6]  P. Shivaram,et al.  Pathological study of elective nephrectomies for a two year period , 2015 .

[7]  A. Lawal,et al.  Adult renal cell carcinoma in Lagos: Experience and challenges at the Lagos University Teaching Hospital , 2012 .

[8]  B. Datta,et al.  Analysis of 88 nephrectomies in a rural tertiary care center of India. , 2012, Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.

[9]  D. Andualem,et al.  Indications, Complications and Mortality of Nephrectomy in Tikur Anbesa General Specialized Hospital , 2012 .

[10]  J. Patard,et al.  Thirty-day mortality after nephrectomy: clinical implications for informed consent. , 2009, European urology.

[11]  J. Patard Incidental renal tumours , 2009, Current opinion in urology.

[12]  T. Badmus,et al.  Adult nephrectomy: our experience at Ile-Ife. , 2008, Nigerian journal of clinical practice.

[13]  T. Badmus,et al.  Malignant renal tumors in adults: a ten-year review in a Nigerian hospital. , 2008, Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.

[14]  M. Rafique Nephrectomy: indications, complications and mortality in 154 consecutive patients. , 2007, JPMA. The Journal of the Pakistan Medical Association.

[15]  I. Gill,et al.  The evolving presentation of renal carcinoma in the United States: trends from the Surveillance, Epidemiology, and End Results program. , 2006, The Journal of urology.

[16]  J. J. Ballesteros Sampol [Indications, morbidity and mortality of the open nephrectomy. Analyses of 681 cases and bibliographic review]. , 2006, Archivos espanoles de urologia.

[17]  S. Campbell,et al.  Renal neoplasms in younger adults: analysis of 112 tumors from a single institution according to the new 2004 World Health Organization classification and 2002 American Joint Committee on Cancer Staging System. , 2005, Archives of pathology & laboratory medicine.

[18]  P. Irby,et al.  Laparoscopic versus open nephrectomy in 210 consecutive patients: Outcomes, cost, and changes in practice patterns , 2003, Surgical Endoscopy And Other Interventional Techniques.

[19]  N. Eke,et al.  Nephrectomy at the University of Port Harcourt Teaching Hospital: a ten-year experience. , 2003, African journal of medicine and medical sciences.

[20]  C. Beisland,et al.  Nephrectomy – Indications, Complications and Postoperative Mortality in 646 Consecutive Patients , 2000, European Urology.

[21]  Taylor Murray,et al.  Cancer statistics, 1999 , 1999, CA: a cancer journal for clinicians.

[22]  T. Ahlering,et al.  Emphysematous pyelonephritis: a 5-year experience with 13 patients. , 1985, The Journal of urology.

[23]  M. Karno,et al.  Renal cell carcinoma. , 1956, Bulletin. Tufts-New England Medical Center.