In vivo tumor targeting and radionuclide imaging with self-assembled nanoparticles: mechanisms, key factors, and their implications.

[1]  Y. Byun,et al.  Heparin-deoxycholic acid chemical conjugate as an anticancer drug carrier and its antitumor activity. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[2]  A. R. Kulkarni,et al.  Paclitaxel-loaded poly(gamma-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancer. , 2006, Biomaterials.

[3]  Minsu Lee,et al.  Size control of self-assembled nanoparticles by an emulsion/solvent evaporation method , 2006 .

[4]  R. Weissleder,et al.  Cell-specific targeting of nanoparticles by multivalent attachment of small molecules , 2005, Nature Biotechnology.

[5]  Shiladitya Sengupta,et al.  Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system , 2005, Nature.

[6]  Kai Qi,et al.  64Cu-labeled folate-conjugated shell cross-linked nanoparticles for tumor imaging and radiotherapy: synthesis, radiolabeling, and biologic evaluation. , 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[7]  Thommey P. Thomas,et al.  Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer. , 2005, Cancer research.

[8]  M. Ferrari Cancer nanotechnology: opportunities and challenges , 2005, Nature Reviews Cancer.

[9]  James H Thrall,et al.  Imaging angiogenesis: applications and potential for drug development. , 2005, Journal of the National Cancer Institute.

[10]  Kwangmeyung Kim,et al.  Physicochemical characterizations of self-assembled nanoparticles of glycol chitosan-deoxycholic acid conjugates. , 2005, Biomacromolecules.

[11]  Mansoor Amiji,et al.  Biodistribution and Targeting Potential of Poly(ethylene glycol)-modified Gelatin Nanoparticles in Subcutaneous Murine Tumor Model , 2004, Journal of drug targeting.

[12]  Ick Chan Kwon,et al.  Preparation and characterization of self-assembled nanoparticles of heparin-deoxycholic acid conjugates. , 2004, Langmuir : the ACS journal of surfaces and colloids.

[13]  L. Brannon-Peppas,et al.  Nanoparticle and targeted systems for cancer therapy. , 2004, Advanced drug delivery reviews.

[14]  M. Bednarski,et al.  Molecular Imaging Applications in Nanomedicine , 2004, Biomedical microdevices.

[15]  Ick Chan Kwon,et al.  Self-assembled nanoparticles based on glycol chitosan bearing 5beta-cholanic acid for RGD peptide delivery. , 2004, Journal of controlled release : official journal of the Controlled Release Society.

[16]  J. Davies,et al.  Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470 , 2004, Nature Medicine.

[17]  F. Marcucci,et al.  Active targeting with particulate drug carriers in tumor therapy: fundamentals and recent progress. , 2004, Drug discovery today.

[18]  S. Sahoo,et al.  Nanotech approaches to drug delivery and imaging. , 2003, Drug discovery today.

[19]  Y. Sugiyama,et al.  Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice. , 2003, Cancer research.

[20]  K. Pavelić,et al.  Medicine on a small scale , 2003, EMBO reports.

[21]  I. Kwon,et al.  Biodistribution and anti-tumor efficacy of doxorubicin loaded glycol-chitosan nanoaggregates by EPR effect. , 2003, Journal of controlled release : official journal of the Controlled Release Society.

[22]  P. Choyke,et al.  Imaging of angiogenesis: from microscope to clinic , 2003, Nature Medicine.

[23]  W. Stetler-Stevenson,et al.  Quantitative assessment of angiogenic responses by the directed in vivo angiogenesis assay. , 2003, The American journal of pathology.

[24]  R. Duncan The dawning era of polymer therapeutics , 2003, Nature Reviews Drug Discovery.

[25]  Vladimir P. Torchilin,et al.  Immunomicelles: Targeted pharmaceutical carriers for poorly soluble drugs , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[26]  J. Folkman,et al.  Clinical translation of angiogenesis inhibitors , 2002, Nature Reviews Cancer.

[27]  D. McDonald,et al.  Significance of blood vessel leakiness in cancer. , 2002, Cancer research.

[28]  S M Moghimi,et al.  Long-circulating and target-specific nanoparticles: theory to practice. , 2001, Pharmacological reviews.

[29]  Y. K. Lee,et al.  A novel formulation for controlled release of heparin-DOCA conjugate dispersed as nanoparticles in polyurethane film. , 2001, Biomaterials.

[30]  P. Carmeliet,et al.  Angiogenesis in cancer and other diseases , 2000, Nature.

[31]  G. Barratt,et al.  Therapeutic applications of colloidal drug carriers. , 2000, Pharmaceutical science & technology today.

[32]  R K Jain,et al.  Openings between defective endothelial cells explain tumor vessel leakiness. , 2000, The American journal of pathology.

[33]  R K Jain,et al.  Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. , 1999, Cancer research.

[34]  R. Jain,et al.  Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[35]  I. Kwon,et al.  Physicochemical Characteristics of Self-Aggregates of Hydrophobically Modified Chitosans , 1998 .

[36]  I. Kwon,et al.  Preparation of chitosan self-aggregates as a gene delivery system. , 1998, Journal of controlled release : official journal of the Controlled Release Society.

[37]  I. Kwon,et al.  Structural determination and interior polarity of self-aggregates prepared from deoxycholic acid-modified chitosan in water , 1998 .

[38]  D. Goldenberg Perspectives on oncologic imaging with radiolabeled antibodies , 1997, Cancer.

[39]  H. Maeda,et al.  SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy. , 1991, Advanced drug delivery reviews.

[40]  L. Laitinen Griffonia simplicifolia lectins bind specifically to endothelial cells and some epithelial cells in mouse tissues , 1987, The Histochemical Journal.

[41]  H. Maeda,et al.  A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. , 1986, Cancer research.

[42]  Ick Chan Kwon,et al.  Self-assembled nanoparticles based on glycol chitosan bearing hydrophobic moieties as carriers for doxorubicin: in vivo biodistribution and anti-tumor activity. , 2006, Biomaterials.