Migration of lead and arsenic from food contact paper into a food simulant and assessment of their consumer exposure safety

ABSTRACT Paper is one of the most commonly used food packaging materials. During the production of packaging paper, it is possible for trace amounts of heavy metals to be incorporated as contaminants. These could migrate into food when packaging paper (food contact paper) is used for cooking, storing and eating. The aim of this study was to determine the migration of lead (Pb) and arsenic (As) from food contact paper into a food simulant and then to assess human safety through the estimated daily intake (EDI) with consumption factor. Migration tests were conducted for 310 samples using 4% acetic acid as a food simulant at 25°C for 10 min and at 95°C for 30 min. Concentrations of Pb and As in a food simulant were quantified by inductively coupled plasma mass spectrometry. LODs for Pb and As were 0.002 and 0.005 µg L−1, respectively. The migration of Pb from food contact paper ranged from not detected (ND) to 17.5 μg L−1 at 25°C for 10 min and from 0.10 to 25.6 μg L−1 at 95°C for 30 min while As ranged from ND to 0.44 μg L−1 at 25°C for 10 min and from ND to 0.87 μg L−1 at 95°C for 30 min. The migration of Pb and As determined in this study confirm that the human exposure was within safe levels based on the EDI of food contact paper compared with the provisional tolerable weekly intake for Pb of 25 μg kg−1 bw and for As of 15 μg kg−1 bw.

[1]  MeeKyung Kim,et al.  Fast and simple determination and exposure assessment of bisphenol A, phenol, p-tert-butylphenol, and diphenylcarbonate transferred from polycarbonate food-contact materials to food simulants. , 2018, Chemosphere.

[2]  G. Mertoglu-Elmas The Effect of Colorants on the Content of Heavy Metals in Recycled Corrugated Board Papers , 2017 .

[3]  N. Banadda,et al.  The Migration of Chemical Contaminants from Polyethylene Bags into Food During Cooking , 2015 .

[4]  L. Lamastra,et al.  Recycled paper-paperboard for food contact materials: contaminants suspected and migration into foods and food simulant. , 2013, Food chemistry.

[5]  Bernd Bilitewski,et al.  Global Risk-Based Management of Chemical Additives II , 2012 .

[6]  Bernd Bilitewski,et al.  Global Risk-Based Management of Chemical Additives I: Production, Usage and Environmental Occurrence , 2012 .

[7]  Jorge C. Oliveira,et al.  Modelling migration from paper into a food simulant , 2011 .

[8]  O. Piringer,et al.  Measurement and modelling of migration from paper and board into foodstuffs and dry food simulants , 2010, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

[9]  Inorganic and organic lead compounds. , 2006, IARC monographs on the evaluation of carcinogenic risks to humans.

[10]  S. Parry,et al.  Migration of inorganic contaminants into dry food from packaging made from recycled paper and board , 2004, Food additives and contaminants.

[11]  E. Skrzydlewska,et al.  Determination of chromium, cadmium and lead in food-packaging materials by axial inductively coupled plasma time-of-flight mass spectrometry , 2003 .

[12]  S. Ellison,et al.  Quantifying uncertainty in analytical measurement , 2000 .

[13]  M. E. Conti The content of heavy metals in food packaging paper boards: an atomic absorption spectroscopy investigation , 1997 .

[14]  J Gilbert,et al.  Migration studies from paper and board food packaging materials. 1. Compositional analysis. , 1997, Food additives and contaminants.

[15]  Joint Fao,et al.  Evaluation of certain food additives and contaminants. Forty-first report of the Joint FAO/WHO Expert Committee on Food Additives. , 1993, World Health Organization technical report series.