Genetic context controls early microglia-synaptic interactions in mouse models of Alzheimer’s disease
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Erik B. Bloss | E. Bloss | G. Howell | K. Onos | Kourtney Graham | Kelly J. Keezer | S. Heuer | Amanda A. Hewes
[1] Martin Fuhrmann,et al. Microglial motility is modulated by neuronal activity and correlates with dendritic spine plasticity in the hippocampus of awake mice , 2023, eLife.
[2] Tuan Leng Tay,et al. Microglia states and nomenclature: A field at its crossroads , 2022, Neuron.
[3] Julie A. Harris,et al. Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia , 2022, Molecular neurodegeneration.
[4] Ravi S. Pandey,et al. LOAD2: A late‐onset Alzheimer’s disease mouse model expressing APOEε4, Trem2*R47H, and humanized amyloid‐beta , 2021, Alzheimer's & Dementia.
[5] Erik B. Bloss,et al. Hippocampal and thalamic afferents form distinct synaptic microcircuits in the mouse infralimbic frontal cortex. , 2021, Cell reports.
[6] Timothy J. Hohman,et al. Protective genes and pathways in Alzheimer’s disease: moving towards precision interventions , 2021, Molecular Neurodegeneration.
[7] Roberto Araya,et al. A spike-timing-dependent plasticity rule for dendritic spines , 2020, Nature Communications.
[8] Robert W. Williams,et al. Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice , 2020, Learning & memory.
[9] Chao Zhang,et al. Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model , 2019, Nature Communications.
[10] Christoph Preuss,et al. Enhancing face validity of mouse models of Alzheimer’s disease with natural genetic variation , 2019, PLoS genetics.
[11] M. Huentelman,et al. Harnessing Genetic Complexity to Enhance Translatability of Alzheimer’s Disease Mouse Models: A Path toward Precision Medicine , 2019, Neuron.
[12] Evan Z. Macosko,et al. Single‐Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell‐State Changes , 2019, Immunity.
[13] B. Stevens,et al. Microglia and the Brain: Complementary Partners in Development and Disease. , 2018, Annual review of cell and developmental biology.
[14] A. Najafi,et al. Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice , 2018, Aging cell.
[15] for the Alzheimer’s Disease Neuroimaging Initiative,et al. Sex differences in Alzheimer disease — the gateway to precision medicine , 2018, Nature Reviews Neurology.
[16] Mark S. Cembrowski,et al. Single excitatory axons form clustered synapses onto CA1 pyramidal cell dendrites , 2018, Nature Neuroscience.
[17] Beth Stevens,et al. Microglia emerge as central players in brain disease , 2017, Nature Medicine.
[18] Benjamin A. Logsdon,et al. Model organism development and evaluation for late‐onset Alzheimer's disease: MODEL‐AD , 2017, Alzheimer's & Dementia.
[19] Sandro Romani,et al. Inhibitory suppression of heterogeneously tuned excitation enhances spatial coding in CA1 place cells , 2017, Nature Neuroscience.
[20] L. Looger,et al. A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons , 2016, Neuron.
[21] Ben A. Barres,et al. Complement and microglia mediate early synapse loss in Alzheimer mouse models , 2016, Science.
[22] A. Najafi,et al. Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology. , 2016, Brain : a journal of neurology.
[23] Mark S. Cembrowski,et al. Structured Dendritic Inhibition Supports Branch-Selective Integration in CA1 Pyramidal Cells , 2016, Neuron.
[24] D. Nicholson,et al. Evidence for Alzheimer’s disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons , 2015, Brain Structure and Function.
[25] Susumu Tonegawa,et al. Conjunctive input processing drives feature selectivity in hippocampal CA1 neurons , 2015, Nature Neuroscience.
[26] Susanne Schoch,et al. Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease , 2014, Neuron.
[27] Christina M. Weaver,et al. Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model , 2014, The Journal of comparative neurology.
[28] J. Morrison,et al. The ageing cortical synapse: hallmarks and implications for cognitive decline , 2012, Nature Reviews Neuroscience.
[29] B. Lamb,et al. Genetic loci modulating amyloid-beta levels in a mouse model of Alzheimer's disease , 2008, Neurobiology of Aging.
[30] Karel Svoboda,et al. Locally dynamic synaptic learning rules in pyramidal neuron dendrites , 2007, Nature.
[31] R. Petersen,et al. Alzheimer's disease and mild cognitive impairment. , 2007, Neurologic clinics.
[32] M. Ohno,et al. Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation , 2006, The Journal of Neuroscience.
[33] Nelson Spruston,et al. Distance-Dependent Differences in Synapse Number and AMPA Receptor Expression in Hippocampal CA1 Pyramidal Neurons , 2006, Neuron.
[34] D. Borchelt,et al. APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1 , 2004, Neurobiology of Aging.
[35] H. Kasai,et al. Structure–stability–function relationships of dendritic spines , 2003, Trends in Neurosciences.
[36] D. Selkoe. Alzheimer's Disease Is a Synaptic Failure , 2002, Science.
[37] Yasushi Miyashita,et al. Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons , 2001, Nature Neuroscience.
[38] T. Freund,et al. Total number and distribution of inhibitory and excitatory synapses on hippocampal CA1 pyramidal cells , 2001, Neuroscience.
[39] J. Morrison,et al. Life and death of neurons in the aging brain. , 1997, Science.
[40] D. Kleinfeld,et al. In vivo dendritic calcium dynamics in neocortical pyramidal neurons , 1997, Nature.
[41] S. Levay,et al. Synaptic patterns in the visual cortex of the cat and monkey. Electron microscopy of Golgi Preparations , 1973, The Journal of comparative neurology.
[42] A. Masurkar. Towards a circuit-level understanding of hippocampal CA1 dysfunction in Alzheimer's disease across anatomical axes. , 2018, Journal of Alzheimer's disease & Parkinsonism.
[43] H. Braak,et al. Neuropathological stageing of Alzheimer-related changes , 2004, Acta Neuropathologica.
[44] Vijaya L. Melnick,et al. Alzheimer’s Dementia , 1985, Contemporary Issues in Biomedicine, Ethics, and Society.