Long-Term Effect of Dust Control on Blood Lead Concentrations

Background. Dust control is recommended to prevent children's exposure to residential lead hazards, but the long-term effect of dust control on children's exposure to environmental lead is unknown. Objective. To determine the effect of dust control on children's exposure to lead, as measured by blood lead concentration at 48 months of age. Design. A randomized, controlled trial. Setting. Rochester, New York. Participants. A total of 275 urban children were randomized at 6 months of age; 189 (69%) were available for the 48-month follow-up blood test. Intervention. Children and their families were randomly assigned to an intervention group that received cleaning equipment and up to 8 visits by a trained lead hazard control advisor or to a control group. The intervention was terminated when the children were 24 months of age. Outcome Measures. Geometric mean blood lead concentration and prevalence of elevated blood lead concentration (ie, ≥10 μg/dL, ≥15 μg/dL, and ≥20 μg/dL), by group assignment. Results. For children with 48-month blood tests, baseline geometric mean blood lead concentrations were 2.8 μg/dL (95% confidence interval [CI]: 2.6,3.0); there were no significant differences in baseline characteristics or lead exposure by group assignment. At 48 months of age, the geometric mean blood lead was 5.9 μg/dL (95% CI: 5.3,6.7) for the intervention group and 6.1 μg/dL (95% CI: 5.5,6.9) for the control group. The percentage of children with a 48-month blood lead ≥10 μg/dL, ≥15 μg/dL, and ≥20 μg/dL was 19% versus 19%, 2% versus 9%, and 1% versus 2% in the intervention and control groups, respectively. Conclusions. We conclude that dust control, as performed by families and in the absence of lead hazard controls to reduce ongoing contamination from lead-based paint, was not effective in preventing children's exposure to residential lead hazards.

[1]  J. Sargent,et al.  Randomized trial of calcium glycerophosphate-supplemented infant formula to prevent lead absorption. , 1999, The American journal of clinical nutrition.

[2]  P. Auinger,et al.  Primary Prevention of Childhood Lead Exposure: A Randomized Trial of Dust Control , 1999, Pediatrics.

[3]  P J Lioy,et al.  The effect of dust lead control on blood lead in toddlers: a randomized trial. , 1999, Pediatrics.

[4]  E W Gunter,et al.  Exposure of the U.S. population to lead, 1991-1994. , 1998, Environmental health perspectives.

[5]  D E Jacobs,et al.  The contribution of lead-contaminated house dust and residential soil to children's blood lead levels. A pooled analysis of 12 epidemiologic studies. , 1998, Environmental research.

[6]  B. Lanphear,et al.  The Paradox of Lead Poisoning Prevention , 1998, Science.

[7]  Mark D. Miller,et al.  Screening for Elevated Blood Lead Levels. , 1998, Pediatrics.

[8]  P. Auinger,et al.  Community characteristics associated with elevated blood lead levels in children. , 1998, Pediatrics.

[9]  N L Winter,et al.  Lead-contaminated house dust and urban children's blood lead levels. , 1996, American journal of public health.

[10]  B. Lanphear,et al.  A RANDOMIZED TRIAL OF THE EFFECT OF DUST CONTROL ON CHILDREN'S BLOOD LEAD LEVELS. † 627 , 1996, Pediatric Research.

[11]  C. Hertzman,et al.  A controlled trial of the effect of HEPA vacuuming on childhood lead exposure. , 1995, Canadian journal of public health = Revue canadienne de sante publique.

[12]  M. J. Brown,et al.  Childhood lead poisoning in Massachusetts communities: its association with sociodemographic and housing characteristics. , 1995, American journal of public health.

[13]  G. Gellert,et al.  Lead poisoning: from screening to primary prevention. , 1993, Pediatrics.

[14]  M. Farfel,et al.  Childhood lead poisoning. A controlled trial of the effect of dust-control measures on blood lead levels. , 1983, The New England journal of medicine.

[15]  Herbert L. Needleman,et al.  Preventing lead poisoning in young children , 1978 .

[16]  D. Satcher Screening Young Children for Lead Poisoning. Guidance for State and Local Public Health Officials - November 1997 , 1997 .

[17]  American Academy of Pediatrics Committee on Environmental Health: Lead poisoning: from screening to primary prevention. , 1993, Pediatrics.