Prevalence and Severity of Gait Disorders in Alzheimer's and Non‐Alzheimer's Dementias

Objectives: To compare the prevalence, severity, and type of gait and balance disorders in Alzheimer's disease (AD), vascular dementia (VaD), Parkinson's disease with dementia (PDD), dementia with Lewy bodies (DLB), Parkinson's disease without dementia (PD), and age‐matched controls.

[1]  Christiane,et al.  World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. , 2004, Journal international de bioethique = International journal of bioethics.

[2]  R. Sulkava,et al.  Dementia with Lewy bodies according to the consensus criteria in a general population aged 75 years or older , 2003, Journal of neurology, neurosurgery, and psychiatry.

[3]  F. Boller,et al.  The neurologic examination in patients with probable Alzheimer's disease. , 1987, Archives of neurology.

[4]  J. Potter,et al.  Non‐neurological factors are implicated in impairments in gait and mobility among patients in a clinical dementia referral population , 2002, International journal of geriatric psychiatry.

[5]  Validation of the NINCDS‐ADRDA Criteria Regarding Gait in the Clinical Diagnosis of Alzheimer Disease: A Clinicopathologic Study , 1995, Alzheimer disease and associated disorders.

[6]  L. Barclay,et al.  Urinary and gait disturbances as markers for early multi-infarct dementia. , 1987, Stroke.

[7]  T. Erkinjuntti Differential diagnosis between Alzheimer's disease and vascular dementia: evaluation of common clinical methods , 1987, Acta neurologica Scandinavica.

[8]  M. Sambrook,et al.  Motor and cognitive function in Lewy body dementia: comparison with Alzheimer's and Parkinson's diseases. , 1997, Journal of neurology, neurosurgery, and psychiatry.

[9]  N. N. Available World medical association declaration of Helsinki , 2000, Chinese Journal of Integrative Medicine.

[10]  T. Brannelly Negotiating ethics in dementia care , 2006 .

[11]  C. Marsden,et al.  Human walking and higher‐level gait disorders, particularly in the elderly , 1993, Neurology.

[12]  M. Grundman,et al.  Dementia: Characteristics of a referral population and factors associated with progression , 1988, Neurology.

[13]  Orthopaedic Surgeons Panel On Falls Prevention Guideline for the Prevention of Falls in Older Persons , 2001 .

[14]  K. Kosaka,et al.  Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB) , 1996, Neurology.

[15]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[16]  F. Huppert,et al.  CAMDEX: A Standardised Instrument for the Diagnosis of Mental Disorder in the Elderly with Special Reference to the Early Detection of Dementia , 1986, British Journal of Psychiatry.

[17]  M. Tinetti,et al.  Fall risk index for elderly patients based on number of chronic disabilities. , 1986, The American journal of medicine.

[18]  L. Waite,et al.  Motor function and disability in the dementias , 2000, International journal of geriatric psychiatry.

[19]  S. O’Keeffe,et al.  Gait disturbance in Alzheimer's disease: a clinical study. , 1996, Age and ageing.

[20]  S. Sahrmann,et al.  Cognitive and motor functioning in Parkinson disease: subjects with and without questionable dementia. , 1998, Archives of neurology.

[21]  I. McKeith,et al.  The Prevalence, Assessment and Associations of Falls in Dementia with Lewy Bodies and Alzheimer’s Disease , 1999, Dementia and Geriatric Cognitive Disorders.

[22]  M. Hennerici,et al.  Are gait disturbances and white matter degeneration early indicators of vascular dementia? , 1994, Dementia.

[23]  Pamela W. Duncan,et al.  Guideline for the Prevention of Falls in Older Persons , 2001 .

[24]  Herman Buschke,et al.  Abnormality of gait as a predictor of non-Alzheimer's dementia. , 2002, The New England journal of medicine.

[25]  M. Tinetti Performance‐Oriented Assessment of Mobility Problems in Elderly Patients , 1986, Journal of the American Geriatrics Society.

[26]  W. Gibb,et al.  The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. , 1988, Journal of neurology, neurosurgery, and psychiatry.

[27]  M. Folstein,et al.  Clinical diagnosis of Alzheimer's disease , 1984, Neurology.