Potential of chicken by-products as sources of useful biological resources.

By-products from different animal sources are currently being utilised for beneficial purposes. Chicken processing plants all over the world generate large amount of solid by-products in form of heads, legs, bones, viscera and feather. These wastes are often processed into livestock feed, fertilizers and pet foods or totally discarded. Inappropriate disposal of these wastes causes environmental pollution, diseases and loss of useful biological resources like protein, enzymes and lipids. Utilisation methods that make use of these biological components for producing value added products rather than the direct use of the actual waste material might be another viable option for dealing with these wastes. This line of thought has consequently led to researches on these wastes as sources of protein hydrolysates, enzymes and polyunsaturated fatty acids. Due to the multi-applications of protein hydrolysates in various branches of science and industry, and the large body of literature reporting the conversion of animal wastes to hydrolysates, a large section of this review was devoted to this subject. Thus, this review reports the known functional and bioactive properties of hydrolysates derived from chicken by-products as well their utilisation as source of peptone in microbiological media. Methods of producing these hydrolysates including their microbiological safety are discussed. Based on the few references available in the literature, the potential of some chicken by-product as sources of proteases and polyunsaturated fatty acids are pointed out along with some other future applications.

[1]  A. Brandelli,et al.  Poultry feather hydrolysate as a protein source for growing rats , 2008 .

[2]  Hiroyuki Yoshida,et al.  Production of Organic Acids and Amino Acids from Fish Meat by Sub‐Critical Water Hydrolysis , 1999, Biotechnology progress.

[3]  E. Márquez,et al.  Proteins, isoleucine, lysine and methionine content of bovine, porcine and poultry blood and their fractions , 2005 .

[4]  P. Bechtel,et al.  Functional properties of protein fractions of channel catfish (Ictalurus punctatus) and their effects in an emulsion system. , 2011, Journal of food science.

[5]  Chia-Ling Jao,et al.  Antioxidative properties of peptides prepared from tuna cooking juice hydrolysates with orientase (Bacillus subtilis) , 2009 .

[6]  L. Chibante Production, characterization and reactions of fullerenes , 1994 .

[7]  S. Nagal,et al.  Feather degradation by strains of Bacillus isolated from decomposing feathers , 2010, Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology].

[8]  Miguel Anxo Murado,et al.  Recovery of Proteolytic and Collagenolytic Activities from Viscera By-products of Rayfish (Raja clavata) , 2009, Marine drugs.

[9]  H. Yoshida,et al.  Conversion of scallop viscera wastes to valuable compounds using sub-critical water , 2006 .

[10]  N. Mahendrakar,et al.  Effect of ensiling and organic solvents treatment on proteolytic enzymes of layer chicken intestine , 2010, Journal of food science and technology.

[11]  A. Brandelli,et al.  Production of an extracellular keratinase from Chryseobacterium sp. growing on raw feathers , 2005 .

[12]  M. Elyachioui,et al.  Process for recycling slaughterhouses wastes and by-products by fermentation , 1998 .

[13]  R. Morawicki,et al.  Enzymatic hydrolysis of poultry meal with endo- and exopeptidases. , 2010, Poultry science.

[14]  Walter F. Schmidt,et al.  Compounding and molding of polyethylene composites reinforced with keratin feather fiber , 2005 .

[15]  Yoshiyuki Shinogi,et al.  Pyrolysis of plant, animal and human waste: physical and chemical characterization of the pyrolytic products. , 2003, Bioresource technology.

[16]  H. Baek,et al.  Evaluation of bitterness in enzymatic hydrolysates of soy protein isolate by taste dilution analysis. , 2007, Journal of food science.

[17]  C. Hyun,et al.  Utilization of bovine blood plasma proteins for the production of angiotensin I converting enzyme inhibitory peptides , 2000 .

[18]  Chyuan-Yuan Shiau,et al.  Free amino acids and peptides as related to antioxidant properties in protein hydrolysates of mackerel (Scomber austriasicus) , 2003 .

[19]  A. Brandelli,et al.  Feather keratin hydrolysis by a Vibrio sp. strain kr2 , 2000, Journal of applied microbiology.

[20]  R. Pérez-Gálvez,et al.  Bi-objective optimisation of the enzymatic hydrolysis of porcine blood protein , 2011 .

[21]  J. Shih,et al.  Nucleotide sequence and expression of kerA, the gene encoding a keratinolytic protease of Bacillus licheniformis PWD-1 , 1995, Applied and environmental microbiology.

[22]  Rani Gupta,et al.  Microbial keratinases and their prospective applications: an overview , 2006, Applied Microbiology and Biotechnology.

[23]  K. Nokihara,et al.  Antioxidative Properties of Histidine-Containing Peptides Designed from Peptide Fragments Found in the Digests of a Soybean Protein. , 1998, Journal of agricultural and food chemistry.

[24]  M. L. L. Martins,et al.  Production and properties of an extracellular protease from thermophilic Bacillus sp , 2004 .

[25]  Gerd Brunner,et al.  Production of amino acids from bovine serum albumin by continuous sub-critical water hydrolysis , 2005 .

[26]  J. Regenstein,et al.  Use of Hydrolysates from Yellowfin Tuna (Thunnus albacares) Heads as a Complex Nitrogen Source for Lactic Acid Bacteria , 2009, Food and Bioprocess Technology.

[27]  Fereidoon Shahidi,et al.  Antioxidative activity and functional properties of protein hydrolysate of yellow stripe trevally (Selaroides leptolepis) as influenced by the degree of hydrolysis and enzyme type , 2007 .

[28]  Rani Gupta,et al.  Keratinases vis-à-vis conventional proteases and feather degradation , 2007 .

[29]  M. Prieto,et al.  Meat By‐Products , 2014 .

[30]  M. Maruyama,et al.  Identification of an antihypertensive peptide derived from chicken bone extract , 2008 .

[31]  R. Radhika,et al.  Lipid profiles of Threadfin bream ( Nemipterus japonicus ) organs , 2009 .

[32]  M. López-Caballero,et al.  Functional and bioactive properties of collagen and gelatin from alternative sources: A review , 2011 .

[33]  P. Dalev An enzyme-alkaline hydrolysis of feather keratin for obtaining aprotein concentrate for fodder , 2005, Biotechnology Letters.

[34]  K. Kida,et al.  Physiological Functions of Enzymatic Hydrolysates of Collagen or Keratin Contained in Livestock and Fish Waste , 2003 .

[35]  W. Gade,et al.  Purification and characterization of aminopeptidase N from chicken intestine with potential application in debittering , 2010 .

[36]  Steve Wilson,et al.  An odor predictive model for rendering applications , 2005 .

[37]  M. C. Papadopoulos Effect of processing on high-protein feedstuffs: A review , 1989 .

[38]  L. Carvalho,et al.  Fish processing waste as a source of alkaline proteases for laundry detergent. , 2009 .

[39]  S. Innis Polyunsaturated fatty acids in human milk: an essential role in infant development. , 2004, Advances in experimental medicine and biology.

[40]  M. Ogawa,et al.  Evaluation of angiotensin I-converting enzyme (ACE) inhibitory activities of hydrolysates generated from byproducts of freshwater clam , 2011 .

[41]  A. Nag,et al.  Production of PUFA Concentrates from Poultry and Fish Processing Waste , 2011 .

[42]  F. Guérard,et al.  Production of tuna waste hydrolysates by a commercial neutral protease preparation , 2002 .

[43]  C. Kumar,et al.  Microbial alkaline proteases: from a bioindustrial viewpoint. , 1999, Biotechnology advances.

[44]  Sung-Hoon Ahn,et al.  Recent Advances in the Application of Natural Fiber Based Composites , 2010 .

[45]  Rozenn Ravallec,et al.  Purification and identification of novel antioxidant peptides from enzymatic hydrolysates of sardinelle (Sardinella aurita) by-products proteins. , 2010 .

[46]  Rodrigo Tarté Meat-Derived Protein Ingredients , 2009 .

[47]  Š. Kormanjoš,et al.  Chemical characteristics of poultry slaughterhouse byproducts , 2009 .

[48]  P. Muthukumar,et al.  Supplementation of Four Protein Percentage to the Basal Diet of Catfish (Mystus cavasius) Fingerlings: To Analyses the Optimum Level of Protein and Body Composition of Fish , 2009 .

[49]  K. Surówka,et al.  Studies on the recovery of proteinaceous substances from chicken heads: II—Application of pepsin to the production of protein hydrolysate , 1994 .

[50]  J. Latshaw,et al.  Indicators of nutritional value of hydrolyzed feather meal. , 2001, Poultry science.

[51]  Xiaodong Zheng,et al.  Keratinase production and keratin degradation by a mutant strain of Bacillus subtilis , 2008, Journal of Zhejiang University SCIENCE B.

[52]  M. Madhusudan,et al.  Purification of alkaline protease from chicken intestine by aqueous two phase system of polyethylene glycol and sodium citrate , 2011, Journal of food science and technology.

[53]  C. Parsons,et al.  Effect of processing systems on protein quality of feather meals and hog hair meals. , 1997, Poultry science.

[54]  Guangrong Huang,et al.  Separation of Iron-Binding Peptides from Shrimp Processing By-products Hydrolysates , 2011 .

[55]  P. Harikumar,et al.  Chicken intestine: A source of aminopeptidases , 2010 .

[56]  N. Haard Specialty enzymes from marine organisms , 1998 .

[57]  A. Błędzki,et al.  Biocomposites reinforced with natural fibers: 2000–2010 , 2012 .

[58]  M. Uddin,et al.  Production of valued materials from squid viscera by subcritical water hydrolysis. , 2010, Journal of environmental biology.

[59]  P. Harikumar,et al.  A rapid autolytic method for the preparation of protein hydrolysate from poultry viscera. , 2008, Bioresource technology.

[60]  Fereidoon Shahidi,et al.  Enzymes from fish and aquatic invertebrates and their application in the food industry , 2001 .

[61]  T. Hayakawa,et al.  Angiotensin I-converting enzyme-inhibitory peptides obtained from chicken collagen hydrolysate. , 2008, Journal of agricultural and food chemistry.

[62]  Julian R.H. Ross,et al.  Catalysis for conversion of biomass to fuels via pyrolysis and gasification: A review , 2011 .

[63]  M. Nasri,et al.  Preparation and use of media for protease-producing bacterial strains based on by-products from Cuttlefish (Sepia officinalis) and wastewaters from marine-products processing factories. , 2008, Microbiological research.

[64]  K. Shirai,et al.  Feasibility of fishmeal replacement by shrimp head silage protein hydrolysate in Nile tilapia (Oreochromis niloticus L) diets , 2002 .

[65]  B. Rasco,et al.  Fish Protein Hydrolysates: Production, Biochemical, and Functional Properties , 2000, Critical reviews in food science and nutrition.

[66]  Q. Beg,et al.  Bacterial alkaline proteases: molecular approaches and industrial applications , 2002, Applied Microbiology and Biotechnology.

[67]  N. M. Rao,et al.  Enzymatic hydrolysis of tannery fleshings using chicken intestine proteases , 1997 .

[68]  M. Kouach,et al.  New antibacterial peptide derived from bovine hemoglobin , 2005, Peptides.

[69]  Jaime López-Cervantes,et al.  Chemical and biological characteristics of protein hydrolysates from fermented shrimp by-products , 2009 .

[70]  J. Bakar,et al.  Fatty Acid Profile of the Oil Extracted from Fish Waste (Head, Intestine and Liver) (Sardinella lemuru) , 2009 .

[71]  N. Mahendrakar,et al.  Protein hydrolysate from visceral waste proteins of Catla (Catla catla): optimization of hydrolysis conditions for a commercial neutral protease. , 2008, Bioresource technology.

[72]  Walter F. Schmidt,et al.  Polyethylene reinforced with keratin fibers obtained from chicken feathers , 2005 .

[73]  Balbir Singh Kaith,et al.  Cellulose-Based Bio- and Nanocomposites: A Review , 2011 .

[74]  Artiwan Shotipruk,et al.  Extraction of protein and amino acids from deoiled rice bran by subcritical water hydrolysis. , 2008, Bioresource technology.

[75]  A. Gousterova,et al.  Assessment of Feather Hydrolysate From Thermophilic Actinomycetes for Soil Amendment and Biological Control Application , 2011 .

[76]  E. Birch,et al.  Essential Fatty Acids in Visual and Brain Dev e l o p m e n t , 2001 .

[77]  G. Ros,et al.  Influence of enzymatic treatment on the nutritional and functional properties of pea flour , 1998 .

[78]  J. Shih,et al.  Evaluation of a Bacterial Feather Fermentation Product, Feather-Lysate, as a Feed Protein , 1991 .

[79]  D. Small,et al.  Generation of meat-like flavourings from enzymatic hydrolysates of proteins from Brassica sp. , 2010 .

[80]  F. Temelli,et al.  Supercritical CO2 Extraction of Oil and Residual Proteins from Atlantic Mackerel (Scomber scombrus) as Affected by Moisture Content , 1997 .

[81]  Se-kwon Kim,et al.  Structure and activity of angiotensin I converting enzyme inhibitory peptides derived from Alaskan pollack skin. , 2002, Journal of biochemistry and molecular biology.

[82]  Hong-Ying Hu,et al.  Optimization of Amino Acids Production from Waste Fish Entrails by Hydrolysis in Sub- and Supercritical Water , 2001 .

[83]  M. Taskin,et al.  Evaluation of waste chicken feathers as peptone source for bacterial growth , 2011, Journal of applied microbiology.

[84]  Kin-tak Lau,et al.  Mechanical and thermal properties of chicken feather fiber/PLA green composites , 2009 .

[85]  R. Sakata,et al.  Determination of angiotensin-I converting enzyme inhibitory peptides in chicken leg bone protein hydrolysate with alcalase. , 2009, Animal science journal = Nihon chikusan Gakkaiho.

[86]  A. Clemente,et al.  Enzymatic protein hydrolysates in human nutrition , 2000 .

[87]  A. Brandelli,et al.  Production of feather protein hydrolysate by keratinolytic bacterium Vibrio sp. kr2. , 2007, Bioresource technology.

[88]  A. Ivankin,et al.  Properties and uses of protein hydrolysates (Review) , 2000, Applied Biochemistry and Microbiology.

[89]  A. Brandelli,et al.  Biochemical features of microbial keratinases and their production and applications , 2010, Applied Microbiology and Biotechnology.

[90]  P. Jaouen,et al.  Enzymatic hydrolysis of cuttlefish (Sepia officinalis) and sardine (Sardina pilchardus) viscera using commercial proteases: effects on lipid distribution and amino acid composition. , 2009, Journal of bioscience and bioengineering.

[91]  B. Bockle,et al.  Reduction of Disulfide Bonds by Streptomyces pactum during Growth on Chicken Feathers , 1997, Applied and environmental microbiology.

[92]  S. Giri,et al.  Nutrient digestibility and intestinal enzyme activity of Clarias batrachus (Linn.) juveniles fed on dried fish and chicken viscera incorporated diets , 2000 .

[93]  M. Linder,et al.  Influence of Hydrolysis Degree on the Functional Properties of Salmon Byproducts Hydrolysates , 2004 .

[94]  D. Deobagkar,et al.  Purification and characterization of an extracellular α-amylase from Bacillus subtilis AX20 , 2005 .

[95]  R. Sakata,et al.  The development of angiotensin I‐converting enzyme inhibitor derived from chicken bone protein , 2008 .

[96]  Se-Kwon Kim,et al.  Bioactive compounds from marine processing byproducts – A review , 2006 .

[97]  L. Yanke,et al.  Selection and characterization of feather-degrading bacteria from canola meal compost , 1999, Journal of Industrial Microbiology and Biotechnology.

[98]  S. N. Jamdar,et al.  Autolytic degradation of chicken intestinal proteins. , 2005, Bioresource technology.

[99]  M. Suphantharika,et al.  Optimization of enzymatic hydrolysis of fish soluble concentrate by commercial proteases , 2005 .

[100]  Serdar Yaman Pyrolysis of Biomass to Produce Fuels and Chemical Feedstocks , 2004 .

[101]  Jinyang Chen,et al.  Hydrolysis technology of biomass waste to produce amino acids in sub-critical water. , 2008, Bioresource technology.

[102]  P. Harnedy,et al.  Bioactive peptides from marine processing waste and shellfish: A review , 2012 .

[103]  Wenjun Li,et al.  Production, characterization and application of keratinase from Streptomyces gulbargensis. , 2009, Bioresource technology.

[104]  M. Holtzapple,et al.  Lime treatment of keratinous materials for the generation of highly digestible animal feed: 1. Chicken feathers. , 2006, Bioresource technology.

[105]  M. Espe,et al.  Nutritional composition of soluble and insoluble fractions obtained by enzymatic hydrolysis of fish-raw materials , 2008 .

[106]  P. Mokrejš,et al.  Processing poultry feathers into keratin hydrolysate through alkaline-enzymatic hydrolysis , 2011, Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA.

[107]  V. K. Modi,et al.  Utilization of meat industry by products: protein hydrolysate from sheep visceral mass. , 2007, Bioresource technology.

[108]  E. Vasileva-Tonkova,et al.  New Protein Hydrolysates from Collagen Wastes Used as Peptone for Bacterial Growth , 2006, Current Microbiology.

[109]  C. Hyun,et al.  Antigenotoxic effects of the peptides derived from bovine blood plasma proteins , 2002 .

[110]  A. Anwar,et al.  Alkaline proteases: A review , 1998 .

[111]  S. Damodaran,et al.  Stability of protease Q against autolysis and in sodium dodecyl sulfate and urea solutions. , 1997, Biochemical and biophysical research communications.

[112]  M. Gómez-Guillén,et al.  Antioxidant and functional properties of gelatin hydrolysates obtained from skin of sole and squid , 2009 .

[113]  F. Sahena,et al.  PUFAs in Fish: Extraction, Fractionation, Importance in Health , 2009 .

[114]  Rani Gupta,et al.  Keratinolytic potential of Bacillus licheniformis RG1: structural and biochemical mechanism of feather degradation. , 2005, Canadian journal of microbiology.

[115]  F. Agblevor,et al.  Storage stability of biocrude oils from fast pyrolysis of poultry litter. , 2012, Waste management.

[116]  J. Shih,et al.  Enumeration of some microbial groups in thermophilic poultry waste digesters and enrichment of a feather-degrading culture. , 1989 .

[117]  Tom Kuppens,et al.  Economics of electricity and heat production by gasification or flash pyrolysis of short rotation coppice in Flanders (Belgium) , 2011 .

[118]  D. Rossi,et al.  Production of High-protein Hydrolysate from Poultry Industry Residue and their Molecular Profiles , 2009 .

[119]  R. E. Rust,et al.  Composition and protein fractions of different meat by-products used for petfood compared with mechanically separated chicken (MSC). , 2000, Meat science.

[120]  E. Croddy Chemical and Biological , 1997 .

[121]  T. Zaghloul,et al.  Biodegradation of native feather keratin by Bacillus subtilis recombinant strains , 2009, Biodegradation.

[122]  Yan Jin,et al.  Purification and identification of novel antioxidant peptides from egg white protein and their antioxidant activities. , 2015, Food chemistry.

[123]  Alane Beatriz Vermelho,et al.  Keratinase Production by Three Bacillus spp. Using Feather Meal and Whole Feather as Substrate in a Submerged Fermentation , 2011, Enzyme research.

[124]  P. Koskinen,et al.  Angiotensin I-converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides. , 2000, The Journal of dairy research.

[125]  A. Brandelli,et al.  Use of Poultry Byproduct for Production of Keratinolytic Enzymes , 2008 .

[126]  M.A.J.S. van Boekel,et al.  Formation of flavour compounds in the Maillard reaction. , 2006 .

[127]  T. Rustad,et al.  Yield and composition of different fractions obtained after enzymatic hydrolysis of cod (Gadus morhua) by-products , 2005 .

[128]  Teresa Korniłłowicz-Kowalska,et al.  Biodegradation of keratin waste: Theory and practical aspects. , 2011, Waste management.

[129]  S. Benjakul,et al.  Protein Hydrolysates from Pacific Whiting Solid Wastes , 1997 .

[130]  B. Alexander,et al.  Chicken blood provides a suitable meal for the sand fly Lutzomyia longipalpis and does not inhibit Leishmania development in the gut , 2010, Parasites & Vectors.

[131]  K. C. Dora,et al.  Optimization of the production of shrimp waste protein hydrolysate using microbial proteases adopting response surface methodology , 2011, Journal of Food Science and Technology.

[132]  R. Barrena,et al.  The use of composting for the treatment of animal by-products: Experiments at lab scale. , 2009, Journal of hazardous materials.

[133]  E Salminen,et al.  Anaerobic digestion of organic solid poultry slaughterhouse waste--a review. , 2002, Bioresource technology.

[134]  R B Choudhary,et al.  Enzyme technology applications in leather processing , 2004 .

[135]  Esther Cascarosa,et al.  Thermochemical processing of meat and bone meal: A review , 2012 .

[136]  Guangyong Zhu,et al.  Hydrolysis technology and kinetics of poultry waste to produce amino acids in subcritical water. , 2010 .

[137]  Y. Tsai,et al.  Production and characterization of keratinase of a feather-degrading Bacillus licheniformis PWD-1. , 1995, Bioscience, biotechnology, and biochemistry.

[138]  H. Byun,et al.  Effect of angiotensin I converting enzyme inhibitory peptide purified from skate skin hydrolysate , 2011 .

[139]  Konrad Bajer,et al.  From feathers to syngas - technologies and devices. , 2012, Waste management.

[140]  Witoon Prinyawiwatkul,et al.  Biochemical and functional properties of herring (Clupea harengus) byproduct hydrolysates , 2003 .

[141]  Arun Sharma,et al.  ANTIOXIDANT AND ACE INHIBITORY PROPERTIES OF POULTRY VISCERA PROTEIN HYDROLYSATE AND ITS PEPTIDE FRACTIONS , 2012 .

[142]  Arun Sharma,et al.  Influence of degree of hydrolysis on functional properties, antioxidant activity and ACE inhibitory activity of peanut protein hydrolysate , 2010 .

[143]  S. Giri,et al.  Growth, feed utilization and carcass composition of catfish Clarias batrachus (Linn.) fingerlings fed on dried fish and chicken viscera incorporated diets , 2000 .

[144]  E. Birch,et al.  Essential fatty acids in visual and brain development , 2001, Lipids.

[145]  S. Rutherfurd Methodology for determining degree of hydrolysis of proteins in Hydrolysates: a review. , 2010, Journal of AOAC International.

[146]  M. Nasri,et al.  Total solubilisation of the chicken feathers by fermentation with a keratinolytic bacterium, Bacillus pumilus A1, and the production of protein hydrolysate with high antioxidative activity , 2011 .

[147]  P. Wanasundara,et al.  Angiotensin I-converting enzyme (ACE) inhibitory activity of hydrolysates obtained from muscle food industry by-products - a short report. , 2005 .

[148]  H. Meier,et al.  Biofuels from waste fish oil pyrolysis: Chemical composition , 2010 .

[149]  G. Lidén,et al.  Semi-continuous co-digestion of solid slaughterhouse waste, manure, and fruit and vegetable waste , 2008 .

[150]  Rudolf Braun,et al.  Enhancement options for the utilisation of nitrogen rich animal by-products in anaerobic digestion. , 2011, Bioresource technology.

[151]  M. Espe,et al.  Chemical composition and theoretical nutritional evaluation of the produced fractions from enzymic hydrolysis of salmon frames with Protamex , 2003 .

[152]  C. Marculescu,et al.  Poultry processing industry waste to energy conversion , 2011 .

[153]  David L Jones,et al.  The environmental and biosecurity characteristics of livestock carcass disposal methods: A review. , 2011, Waste management.

[154]  E. B. Kurbanoğlu,et al.  A new process for the utilization as peptone of ram horn waste , 2002 .

[155]  Chi-Yue Chang,et al.  Antioxidant properties and protein compositions of porcine haemoglobin hydrolysates , 2007 .

[156]  Jianping Wu,et al.  Feather Fiber‐Based Thermoplastics: Effects of Different Plasticizers on Material Properties , 2013 .

[157]  O. Pancorbo,et al.  Stabilization of poultry processing by-products and poultry carcasses through direct chemical acidification , 1995 .

[158]  F. Sahena,et al.  Fatty acid compositions of fish oil extracted from different parts of Indian mackerel (Rastrelliger kanagurta) using various techniques of supercritical CO2 extraction. , 2010 .

[159]  H. Suh,et al.  Feather-degrading Bacillus species from poultry waste , 2001 .

[160]  W. H. Rulkens,et al.  Recovery of valuable nitrogen compounds from agricultural liquid wastes: potential possibilities, bottlenecks and future technological challenges , 1998 .

[161]  M. Nasri,et al.  Preparation and testing of Sardinella protein hydrolysates as nitrogen source for extracellular lipase production by Rhizopus oryzae , 2005 .

[162]  T. Ohmori,et al.  Chicken collagen hydrolysate protects rats from hypertension and cardiovascular damage. , 2010, Journal of medicinal food.

[163]  A. Motamedzadegan,et al.  Optimization of Enzymatic Hydrolysis of Visceral Waste Proteins of Yellowfin Tuna (Thunnus albacares) , 2012, Food and Bioprocess Technology.

[164]  F. Toldrá,et al.  The use of muscle enzymes as predictors of pork meat quality , 2000 .

[165]  S. Jamdar,et al.  Radiation decontamination of poultry viscera , 2008 .

[166]  B. Simpson,et al.  Concentrating PUFA from mackerel processing waste , 2003 .

[167]  Adriane Grazziotin,et al.  Hidrolisado de penas como fonte de proteína para ratos , 2008 .

[168]  F. Cabral,et al.  Fractionation of fish oil with supercritical carbon dioxide , 2008 .

[169]  X Flotats,et al.  Anaerobic digestion of slaughterhouse waste: main process limitations and microbial community interactions. , 2011, Bioresource technology.