Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulin.
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T. Fojo | F. Loganzo | M. Poruchynsky | L. Greenberger | S. Ayral-Kaloustian | A. Zask | Malathi Hari | T. Annable | X. Tan | Daniel B Morilla | S. Musto | Joshua A Kaplan | A. Minnick | M. K. May