A toxicogenomic study for the investigation of genotoxicity-related signaling networks in long-term and low dose lead exposed rat kidney

[1]  M. Gallegos-Corona,et al.  Silymarin and dimercaptosuccinic acid ameliorate lead-induced nephrotoxicity and genotoxicity in rats , 2016, Human & experimental toxicology.

[2]  M. Karimfar,et al.  Long-Term Exposure of Lead Acetate on Rabbit Renal Tissue , 2016, Iranian Red Crescent medical journal.

[3]  A. Oyagbemi,et al.  Lack of reversal of oxidative damage in renal tissues of lead acetate‐treated rats , 2015, Environmental toxicology.

[4]  W. Liang,et al.  REDD1 and p-AKT over-expression may predict poor prognosis in ovarian cancer. , 2014, International journal of clinical and experimental pathology.

[5]  E. Solary,et al.  The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases , 2014, Leukemia.

[6]  J. Kwon,et al.  Recent Advances in In Vivo Genotoxicity Testing: Prediction of Carcinogenic Potential Using Comet and Micronucleus Assay in Animal Models , 2013, Journal of cancer prevention.

[7]  Chun-Xiao Song,et al.  Potential functional roles of DNA demethylation intermediates. , 2013, Trends in biochemical sciences.

[8]  Y. Seo,et al.  Toxicogenomic approaches for understanding molecular mechanisms of heavy metal mutagenicity and carcinogenicity. , 2013, International journal of hygiene and environmental health.

[9]  Ethan D Buhr,et al.  Molecular components of the Mammalian circadian clock. , 2013, Handbook of experimental pharmacology.

[10]  A. Tiwari,et al.  Toxicity of lead: A review with recent updates , 2012, Interdisciplinary toxicology.

[11]  M. Dkhil,et al.  The protective effect of flaxseed oil on lead acetate-induced renal toxicity in rats. , 2011, Journal of hazardous materials.

[12]  K. Rajewsky,et al.  Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice , 2011, Proceedings of the National Academy of Sciences.

[13]  J. Freeman,et al.  Global Gene Expression Analysis Reveals Dynamic and Developmental Stage–Dependent Enrichment of Lead-Induced Neurological Gene Alterations , 2010, Environmental health perspectives.

[14]  L. Aravind,et al.  Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2 , 2010, Nature.

[15]  S. Kimball,et al.  ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression. , 2009, Biochemical and biophysical research communications.

[16]  Peter A. Jones,et al.  Cancer epigenetics: modifications, screening, and therapy. , 2008, Annual review of medicine.

[17]  M. Antoch,et al.  Circadian proteins in the regulation of cell cycle and genotoxic stress responses. , 2007, Trends in cell biology.

[18]  J. Duruibe,et al.  Heavy metal pollution and human biotoxic effects , 2007 .

[19]  J. Takahashi,et al.  Molecular components of the mammalian circadian clock. , 2006, Human molecular genetics.

[20]  P. Vokonas,et al.  Low-Level Lead Exposure, Metabolic Syndrome, and Heart Rate Variability: The VA Normative Aging Study , 2006, Environmental health perspectives.

[21]  S. Gery,et al.  The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells. , 2006, Molecular cell.

[22]  Inorganic and organic lead compounds. , 2006, IARC monographs on the evaluation of carcinogenic risks to humans.

[23]  Aziz Sancar,et al.  Coupling of Human Circadian and Cell Cycles by the Timeless Protein , 2005, Molecular and Cellular Biology.

[24]  Kevin R Hayes,et al.  Advances in toxicogenomics. , 2005, Chemical research in toxicology.

[25]  Cheng Chi Lee.  The circadian clock and tumor suppression by mammalian period genes. , 2005, Methods in enzymology.

[26]  J. Woodcock,et al.  Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective , 2004, Nature Reviews Drug Discovery.

[27]  P. Lord.  Progress in applying genomics in drug development. , 2003, Toxicology letters.

[28]  H. Needleman.  Lead poisoning. , 2004, Annual review of medicine.

[29]  S. Yamaguchi,et al.  Control Mechanism of the Circadian Clock for Timing of Cell Division in Vivo , 2003, Science.

[30]  K Wyszynska,et al.  Genotoxic effects of occupational exposure to lead and cadmium. , 2003, Mutation research.

[31]  Paramjit Grover,et al.  DNA damage in workers exposed to lead using comet assay. , 2003, Toxicology.

[32]  R. Jaenisch,et al.  Chromosomal Instability and Tumors Promoted by DNA Hypomethylation , 2003, Science.

[33]  M. Kastan,et al.  DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation , 2003, Nature.

[34]  A. Yang,et al.  REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species. , 2002, Molecular cell.

[35]  J. Pevsner,et al.  Microarray analysis of differential gene expression in lead-exposed astrocytes. , 2001, Toxicology and applied pharmacology.

[36]  K. Jamil,et al.  Genotoxic effect of lead nitrate on mice using SCGE (comet assay). , 2000, Toxicology.

[37]  P. Vokonas,et al.  Electrocardiographic conduction disturbances in association with low-level lead exposure (the Normative Aging Study). , 1998, The American journal of cardiology.

[38]  A. Carr,et al.  Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[39]  S. Schreiber,et al.  Overexpression of a kinase‐inactive ATR protein causes sensitivity to DNA‐damaging agents and defects in cell cycle checkpoints , 1998, The EMBO journal.

[40]  M. Loghman‐Adham.  Renal effects of environmental and occupational lead exposure. , 1997, Environmental health perspectives.

[41]  A. Rotnitzky,et al.  The relationship of bone and blood lead to hypertension. The Normative Aging Study. , 1996, JAMA.

[42]  A. Rotnitzky,et al.  A longitudinal study of low-level lead exposure and impairment of renal function. The Normative Aging Study. , 1996, JAMA.

[43]  Ronald W. Davis,et al.  Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray , 1995, Science.

[44]  T. Oberley,et al.  Effects of lead administration on developing rat kidney. II. Functional, morphologic, and immunohistochemical studies. , 1995, Toxicology and applied pharmacology.

[45]  C. Bulpitt,et al.  Impairment of renal function with increasing blood lead concentrations in the general population. The Cadmibel Study Group. , 1992, The New England journal of medicine.

[46]  J. Schwartz,et al.  Lead, blood pressure, and cardiovascular disease in men and women. , 1991, Environmental health perspectives.

[47]  R. Herber,et al.  Influence of occupational low-level lead exposure on renal parameters. , 1987, American journal of industrial medicine.