NG108-15 cell-based and protein phosphatase inhibition assays as alternative semiquantitative tools for the screening of lipophilic toxins in mussels. Okadaic acid detection.

[1]  J. Diogène,et al.  Improvements in the use of neuroblastomaxglioma hybrid cells (NG108-15) for the toxic effect quantification of marine toxins. , 2010, Toxicon : official journal of the International Society on Toxinology.

[2]  D. Mountfort,et al.  Assessment of protein phosphatase in a re-usable rapid assay format in detecting microcystins and okadaic acid as a precursor to biosensor development. , 2008, Toxicon : official journal of the International Society on Toxinology.

[3]  J. Diogène,et al.  Comparative study of the use of neuroblastoma cells (Neuro-2a) and neuroblastomaxglioma hybrid cells (NG108-15) for the toxic effect quantification of marine toxins. , 2008, Toxicon : official journal of the International Society on Toxinology.

[4]  S. Moukha,et al.  Evaluation of the cytotoxicity and genotoxicity of extracts of mussels originating from Moroccan Atlantic coast, in human colonic epithelial cells Caco‐2 , 2008, Environmental toxicology.

[5]  N. Melchiorre,et al.  A cytolytic assay for the measurement of palytoxin based on a cultured monolayer cell line. , 2008, Analytical biochemistry.

[6]  L. Botana,et al.  Lipophilic toxin profile in Galicia (Spain): 2005 toxic episode. , 2007, Toxicon : official journal of the International Society on Toxinology.

[7]  M. Dechraoui,et al.  Use of two detection methods to discriminate ciguatoxins from brevetoxins: application to great barracuda from Florida Keys. , 2005, Toxicon : official journal of the International Society on Toxinology.

[8]  G. Eaglesham,et al.  Multiresidue method for determination of algal toxins in shellfish: single-laboratory validation and interlaboratory study. , 2005, Journal of AOAC International.

[9]  Gian Paolo Rossini,et al.  Functional assays in marine biotoxin detection. , 2005, Toxicology.

[10]  M. Vieytes,et al.  Development of a F actin-based live-cell fluorimetric microplate assay for diarrhetic shellfish toxins. , 2003, Analytical biochemistry.

[11]  S. Musser,et al.  Confirmation of brevetoxin metabolism in the Eastern oyster (Crassostrea virginica) by controlled exposures to pure toxins and to Karenia brevis cultures. , 2002, Toxicon : official journal of the International Society on Toxinology.

[12]  G. Rossini,et al.  Cytotoxic responses to unfractionated extracts from digestive glands of mussels. , 2002, Toxicon : official journal of the International Society on Toxinology.

[13]  M. Kane,et al.  A cytotoxicity assay for the detection and differentiation of two families of shellfish toxins. , 2001, Toxicon : official journal of the International Society on Toxinology.

[14]  D. Mountfort,et al.  Protein phosphatase inhibition assay adapted for determination of total DSP in contaminated mussels. , 2001, Toxicon : official journal of the International Society on Toxinology.

[15]  F. Mazzei,et al.  Evaluation of rapid methods for the determination of okadaic acid in mussels , 2001, Journal of applied microbiology.

[16]  Ian Garthwaite,et al.  Keeping shellfish safe to eat: a brief review of shellfish toxins, and methods for their detection , 2000 .

[17]  A. Tubaro,et al.  Methodological improvement of the protein phosphatase inhibition assay for the detection of okadaic acid in mussels. , 1999, Natural toxins.

[18]  S. Musser,et al.  Monitoring brevetoxins during a Gymnodinium breve red tide: comparison of sodium channel specific cytotoxicity assay and mouse bioassay for determination of neurotoxic shellfish toxins in shellfish extracts. , 1999, Natural toxins.

[19]  R. Dickey,et al.  Detection of DSP-toxins, okadaic acid, and dinophysis toxin-1 in shellfish by serine/threonine protein phosphatase assay. , 1996, Journal of AOAC International.

[20]  T. Yasumoto,et al.  Suitability of the MTT-based cytotoxicity assay to detect okadaic acid contamination of mussels. , 1996, Toxicon : official journal of the International Society on Toxinology.

[21]  T. Yasumoto,et al.  A protein phosphatase 2A inhibition assay for a fast and sensitive assessment of okadaic acid contamination in mussels. , 1996, Toxicon : official journal of the International Society on Toxinology.

[22]  M. Wekell,et al.  Tetrazolium-based cell bioassay for neurotoxins active on voltage-sensitive sodium channels: semiautomated assay for saxitoxins, brevetoxins, and ciguatoxins. , 1993, Analytical biochemistry.

[23]  A. Takai,et al.  Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics. , 1988, The Biochemical journal.

[24]  T. Yasumoto,et al.  Occurrence of a new type of shellfish poisoning in the Tohoku district. , 1978 .